🧠 Curious Science Microlesson 🔬 ❓ What is DNA, and why is it important? 🙋 DNA, or deoxyribonucleic acid, is the molecule that carries the genetic instructions for life. ⏳ Discovered in 1953 by James Watson and Francis Crick, DNA's double helix structure revealed how genetic information is stored and passed down from generation to generation. 💡 DNA is composed of two strands forming a double helix, made up of nucleotides. Each nucleotide contains a sugar, a phosphate group, and a nitrogenous base (adenine, thymine, cytosine, or guanine). The sequence of these bases encodes genetic information. 🔍 DNA is crucial for inheritance, coding for proteins, and guiding the development and functioning of living organisms. Mutations in DNA can lead to genetic disorders and genetic variations can lead to adaptation. 🌎 Understanding DNA has revolutionized medicine, forensics, and biology. It allows for genetic testing, personalized medicine, and advancements in biotechnology. 🎯 Extract DNA from a fruit like a strawberry using household items. Observe the DNA strands and discuss the importance of this molecule in living organisms. #Science #HAMSTER #SchoolAlive
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Business is fascinating. Biology is beautiful. But when Biology applies Business principles, that's AWESOME!!!!!! 😃😃😃 There are two kinds of cells: prokaryotic and eukaryotic. 1️⃣ A prokaryotic cell is a big empty space where everything happens. There are no specialized structures in charge of specific tasks. DNA replication, protein synthesis, energy production, everything happens in a large shared space. 2️⃣ A eukaryotic cell is quite different. There are specialized structures, each of which is responsible for a very specific task. The DNA doesn't simply float around: it is hosted inside the nucleus. Proteins aren't assembled in the middle of nowhere. They are assembled in the endoplasmatic reticulum, then transported to the Golgi Complex to get some extra carbs (literally. They're important for the protein to interact with other molecules), then carried to where they have to be by actine molecules that "walk" over myosin "rails" from the cytoskeleton. All this is powered by energy, which is also generated in a specialized structure: the mitochondria. 👉 Eukariotic cells divide labor. They organize. They specialize. 👉 Prokariotic cells do not. That's why we call these cells prokariotic (= simple) and eukariotic (=good). ‼️ ALL multicellular organisms are eukariotic. 🦋 🐸 Only cells that have structures with designated roles and activities can manage the complexity of a multicellular being. 🐋 🎯 Think carefully about how you design roles and assign responsibilities: it's the secret to managing complexity. #management #business #cellular #biology
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Revolutionizing Genetic Engineering with CReATiNG: A Game-Changer in Synthetic Biology! Exciting news from the USC Dornsife College of Letters, Arts and Science unveils a groundbreaking technique that is set to transform the field of synthetic biology. Known as CReATiNG (Cloning Reprogramming and Assembling Tiled Natural Genomic DNA), this innovative method offers a simpler and more cost-effective approach to constructing synthetic chromosomes. Lead by researcher Ian Ehrenreich, this cutting-edge technique involves cloning and reassembling natural DNA segments from yeast, enabling the creation of synthetic chromosomes that can replace their native counterparts in cells. CReATiNG opens up possibilities for combining chromosomes between different yeast strains and species, altering chromosome structures, and simultaneously deleting multiple genes. This revolutionary advancement has the potential to significantly advance genetic engineering, leading to breakthroughs in medicine, biotechnology, biofuel production, and even space exploration. Stay tuned as CReATiNG paves the way for a new era of innovation in synthetic biology! #SyntheticBiology #GeneticEngineering #Biotechnology #InnovationInScience #BiomedicalEngineering
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Nice article about the Autoinjector and our founders in the UMN News https://lnkd.in/gb-sWusE
Researchers constructed a robot that uses machine learning to fully automate a complicated microinjection robot used in genetics research. The paper co-led by graduate students Andrew Alegria and Amey Joshi was featured on the cover of the April 2024 issue of Genetics. Read more at https://lnkd.in/gUqRaQgZ University of Minnesota // University of Minnesota Genomics Center // SUHASA KODANDARAMAIAH // Daryl Gohl // NSF ERC Advanced Technologies for the Preservation of Biological Systems (ATP-Bio) // The National Institutes of Health // National Science Foundation (NSF) // Objective Biotechnology // Genetics Society of America
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Climate mitigation tech expertise plus Genetics, and AI/ML based in silico Biology to study Genome, Microbiome , Food Security; corner-stones of Deep-Tech Science are my areas of expertise
I have entered Biology via Chemistry, through Molecular Biology, under the gaze of Big Foundational folks of molecular Biology, such as Gerry Smith, Frank Stahl, Ethan Signer. They earlier studied under Boris Magasanik of MIT, Max Delbruck of Caltech and Francois Jacob of France. They have been the absolutely highesst level people of Microbiology and Molecular Biology deeply influenced by Linus Pauling in the one hand and Salvador Luria (In whose priximity I used to sit in MIT) on the other. Chemistry meeting Biology, whirlpool of ideas; I am part of that big family. The Science I do always reflects the combined intellect of that heredity that provenance. My mother enjoined me to be modest to tread gently on the soil. But the interlocutors who discuss genetics with me or wonder about my claim in Science, I would urge them to look up those people cited above, as well as know what I have done before, and understand which intellectual family I come from. In spite of that academic lineage and my proximity with the Titans of Biology or perhaps because of that I now realise that the ideas originated by Pauling and Delbruck and nurtured by Watson and Crick and now propagated by Jennifer Doudna and the gene-editing folks is inadequate to address coming Climate and Food InSecurity Peril. The most important phenotypes are a twisted web of genetics, epigenetics and non-genetic factor. Natural variation is not just genetic; natural variation cannot be created by gene editing. Gene editing will simply create a small tiny DNA based change while the phenotype is caused by chromatin remodelling meta-events, chromosomal biophysical events, deep heritable metabolic factors all revealed in Nature and cannot be created in the laboratory. That is why Biology must be learned in Nature, Best Rice mutations and variation can only be found in the Rice field. To think like that and to find ways of doing it will be the best Science of the coming era. #Science in Kanihati #Beyond reductionism #Let a hundred flowers blossom #Innovation by Farmers is the best innovation
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The Human Genome Research Institute established the 25th of April as DNA Day to commemorate the discovery of the DNA double helix structure and the completion of the Human Genome Project. As advocates for biotechnology advancement and enthusiasts of DNA research, we're joining in the celebration by compiling a list of interesting facts and marvels about this integral area of science. 🧬 DNA serves as an intricate code, dictating the blueprint for everything from hair colour to muscle development. Comprised of just four unique letters — A, G, C, and T — the sequence of these letters defines individual characteristics. 🧬Despite our apparent differences, humans share an astounding 99.9% of DNA with one another, underscoring our fundamental similarities. It's the mere 0.1% variation that distinguishes each of us, such as our distinct eye colours. 🧬 The sheer length of DNA within the body is staggering; if unfurled and laid end to end, it could stretch from Earth to the Sun and back over 600 times. 🧬 Biotechnology harnesses the power of DNA manipulation to revolutionise industries such as medicine, agriculture, and environmental science. Through techniques like genetic engineering, scientists can modify DNA to produce therapeutic proteins, enhance crop yields, and mitigate pollution. 🧬 Surprisingly, our genetic makeup bears resemblance to that of a banana, with approximately 60% of our DNA overlapping. This highlights the interconnectedness of all living organisms. 🧬 DNA holds the key to unlocking personalised medicine, where treatments are tailored to an individual's genetic makeup, maximizing efficacy and minimising side effects. 🧬Despite its resilience, DNA is susceptible to damage from various sources like UV radiation or environmental toxins. While cellular repair mechanisms strive to rectify these errors, mutations can occur, occasionally resulting in diseases. What fact about DNA fascinated you most? Share with your thoughts with us! #DNADay #Biotech #UVUBio #SouthAfrica
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Microbiologist & Author of the newsletter BioVerse Firefly | Bridging the Gap Between Biological Science & Society
Hey friends, Andrew here. Today I'll be sharing my next review on the topic relating to recombinant DNA technology. Long story short, it is a compilation of technology and techniques which helps molecular biologists to study the characteristics of a gene and its protein. The technology itself overlaps with other fields like bioinformatics and synthetic biology. By combining the various knowledge from different fields, a sustainable synthetic product (natural product) may be discovered. Through this discovery, the product can then be fine tuned so that it can be reproduced under laboratory and industrial conditions. Here's an overview of what recombinant DNA technology. Take note that the poster contains simplified points to help with the understanding of the concept and how the technology works. Hope you guys enjoy this type of content and have a great week 😊 #Biotechnology #MolecularBiology #Sustainability
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Young retired civil engineer (telecoms) still very active in digital edition, translations and blogging
Rain may have helped form the first cells, kick-starting life as we know it - https://lnkd.in/eSur8UdH - Billions of years of evolution have made modern cells incredibly complex. Inside cells are small compartments called organelles that perform specific functions essential for the cell’s survival and operation. For instance, the nucleus stores genetic material, and mitochondria produce energy.…<p class="more-link-p"><a class="more-link" href="">Read more →</a></p>
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🔬✨ Today, we celebrate a groundbreaking scientific advancement: the discovery of the double helix structure of DNA! 🧬 On July 25, 1953, James Watson and Francis Crick published their model of the DNA structure, unveiling the secret of life itself. This discovery transformed our understanding of biology, paving the way for countless innovations in medicine, genetics, and biotechnology. 🌱🧬 🔍 The double helix structure of DNA allowed scientists to understand how genetic information is stored and transmitted from generation to generation. This model was a true breakthrough, showing how base pairs form and replicate. 💡 This discovery reminds us of the importance of scientific curiosity, collaboration, and perseverance. Today's innovations are built on the foundations laid by visionary researchers. 📈 Let's continue to explore, question, and push the boundaries of knowledge. The future of science and medicine depends on our passion for discovery and our commitment to progress. #DNA #ScientificDiscovery #Biotechnology #Inspiration #Science
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I've been working through my reading list and just finished reading Origins by Asimov Press, and I have to say, it is a fantastic dive into the world of synthetic biology and gene editing. The book does an excellent job of breaking down complex scientific concepts in a way that is easy to understand and, at times, conversational. Origins takes you on a journey from the beginnings of life to the knife's edge in biotech. It covers everything from how gene editing works to its potential applications in medicine, agriculture, and tackling climate change. The explanations are clear and straightforward, making it a great read for anyone curious about these topics. If you are looking for a digestible primer on SynBio's past and how it is shaping our future, I highly recommend checking out Origins. It is insightful, well-written, and eye-opening. Here are also the authors and their contributions: 1. Synthetic Origins - Michael Elowitz 2. Making the Micropipette - Metacelsus 3. Engineering Ants - Taylor Hart, PhD 4. Fast Biology - Niko McCarty 5. What Science Can Learn from Car Mechanics - Trevor Klee 6. Discovering an Antimalarial Drug in Mao's China - Wendi Yan 7. Making Cells Young - Jose Luis Ricón Fernández de la Puente 8. Scaling Phage Therapy - Tom Ireland 9. Deliberate Dysentary - Jake Eberts 10. Blocked Transmission - Tom Ough 11. The Vector Zoo - Xander Balwit #SyntheticBiology #GeneEditing #Biotechnology #ScienceBooks #MustRead #AsimovPress
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