Exciting research on R399E potential for osteoarthritis treatment! Learn how it could restore joints and relieve pain. (https://lnkd.in/eHy2n_df) https://lnkd.in/eVwmmeMr #Osteoarthritis #Jointpain #GDF5 #animalwelfare Kerstin Kleinschmidt-Doerr Christian Brenneis Stephanie Herzog Hans Guehring Frances Henson MA VetMB PhD CertES Cert EM DipECVSMR Christian Thudium Kyra Cowan Djordje Musil Merck Healthcare
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Most attention is paid to excessive bone formation in axSpA, but the disease is also accompanied by excessive bone loss. In our cohort of 126 r-axSpA patients treated with TNF inhibitors for 8 years in daily clinical practice, BMD increased significantly, especially during the first 4 years of treatment and stabilized thereafter. This effect was most pronounced in the LS and, as expected, small in the hip. Radiographic vertebral fractures continued to develop or progressed, irrespective of improvement in BMD. Therefore, clinical attention for loss of bone density of the spongy bone and the occurrence of vertebral fractures is important. Interested? You can read more in our recently published article from the GLAS cohort:
Improvement of bone mineral density and new vertebral fractures during 8 years of TNF-α inhibition in patients with axial spondyloarthritis
sciencedirect.com
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Check out this important clinical data on the treatment of overactive bladder. For patients with urgency urinary incontinence unresponsive to antimuscarinic therapy, both AUA and EAU guidelines recommend considering intravesical injection of botulinum toxin A. This treatment has demonstrated efficacy in multiple randomized, placebo-controlled trials, significantly improving urinary incontinence episodes, maximum cystometric capacity, and maximum detrusor pressure. Botulinum toxin A works by inhibiting neurotransmitter release and reducing central sensitization, offering a promising option for patients with refractory overactive bladder. Caldera Medical is dedicated to supporting you with valuable resources to enhance patient care. Click the link below to read more on this. #CalderaMedical #OveractiveBladder #BotulinumToxinA #ClinicalData #DoctorResources #PatientCare #MedicalGuidelines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810204/
ncbi.nlm.nih.gov
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Consultant Vascular Surgeon @ IRCCS Istituto Auxologico Italiano, Milan, Italy || PhD Candidate @ UNIMI || Medical Writer and Healthcare Consultant
Beautiful #systematic #review on the effectiveness of #carotid #endarterectomy (CEA). Since the 1970s, the stroke rate in patients with #asymptomatic #stenosis has decreased by 25% every 5 years (it's worth noting that the clinical trials on which the indications for CEA are based were conducted in the 1990s and early 2000s). In contrast, the number of patients receiving #best #medical #treatment (#antiplatelet + #statin) has increased, and there has been a significant decrease in smokers. Furthermore, it is important to highlight that the stroke rate is significant only for stenosis >80%. Who still treat surgically #asymptomatic #carotid #stenosis? https://lnkd.in/d2iSVghP
Temporal Trends and Determinants of Stroke Risk in Patients With Medically Treated Asymptomatic Carotid Stenosis
ahajournals.org
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Explore our latest open access article on the risk of post-injection endophthalmitis peaking within the first three injections of anti-vascular endothelial growth factor therapy: A nationwide registry-based study. 🔗 https://lnkd.in/djXZEmxa #eyehealth #ophthalmology
Risk of post‐injection endophthalmitis peaks within the first three injections of anti‐vascular endothelial growth factor therapy: A nationwide registry‐based study
onlinelibrary.wiley.com
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Ophthopedia Update:The impact of achieving target intraocular pressure on glaucomatous retinal nerve fiber layer thinning in a treated clinical population: Estimate the effect of being below and above the clinician-set target intraocular pressure (IOP) on rates of glaucomatous retinal nerve fiber layer (RNFL) thinning in a treated real-world clinical population. #Ophthalmology #Ophthotwitter #Scicomm
The impact of achieving target intraocular pressure on glaucomatous retinal nerve fiber layer thinning in a treated clinical population
ajo.com
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#Nephrostomydevices industry is anticipated to register 8.3% CAGR between 2023 and 2032 due to rising prevalence of kidney disorders and increased adoption of minimally invasive #surgicalprocedure.
Nephrostomy Devices Market to exceed USD 2.4 billion by 2032, Says Graphical Research Powered by GMI
globenewswire.com
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76 years-old female patient with history of arterial hypertension, dyslipidemia and ischemic cardiomyopathy (coronary angioplasty of LAD and RCA in 2022). Clinical presentation: Severe intermittent claudication of the left limb (Rutherford 3 <100 m). Angiography revealed severe stenosis in the proximal portion of the SFA, occlusion of the mid and distal portion of the SFA, occlusion of popliteal P1 segment and severe stenosis of the proximal en mid portion of the anterior tibial artery. Strategy: Antegrade US-guided puncture of left CFA and 6 Fr sheath placement. Antegrade and endoluminal crossing of the fem-pop occlusion with the support of a Rubicon 0.018” catheter and a V-18 guidewire. Angioplasty with a 3.5 mm x 150 mm balloon of anterior tibial artery. Pre-dilatation of the fem-pop segment with a 5 mm x 150 mm balloon and subsequent dilatation with a 5 mm x 150 mm DCB. Extensive and flow-limiting disection after DCB. 5 mm x 150 mm Jaguar stent (Balton®) placement in the fem-pop segment and two 6 mm x 120 mm Eluvia stents (Boston Scientific®) in the proximal and mid portion of the SFA. Post-dilatation with 5 mm x 150 mm balloon (fem-pop) and 6 mm x 200 mm balloon (SFA). Good direct flow to the foot and patency of the three infrapopliteal vessels. On her outpatient follow-up, she reported complete resolution of claudication symptoms. #peripheralarterydisease #cli #clti #clifighters #limbsalvage #endovascular #vascular #medicine #hospital #angiography #vascularnews Luís Loureiro 🇪🇺 Fawaz Bardooli
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Ophthopedia Update:Long-term Treatment Patterns for Diabetic Macular Edema: Up to 6-Year Follow-Up in the IRIS® Registry: To characterize anti-vascular endothelial growth factor (VEGF) intravitreal therapy (IVT) patterns and long-term visual outcomes among patients with diabetic macular edema (DME) in routine clinical practice in the United States. #Ophthalmology #Retina #Ophthotwitter
Long-term Treatment Patterns for Diabetic Macular Edema: Up to 6-Year Follow-Up in the IRIS® Registry
ophthalmologyretina.org
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The consensus reached by a panel of experts in the United States regarding the standard naming and diagnosis of neuropathic pruritus is now available. This unified approach aims to streamline the identification and treatment of this condition. Find out more at the provided link. #NeuropathicPruritus #MedicalConsensus
United States expert panel consensus on uniform nomenclature and diagnosis for neuropathic pruritus
ivancevichmd.blogspot.com
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A Complete Guide of " 𝐈𝐧𝐟𝐮𝐬𝐢𝐨𝐧 𝐏𝐮𝐦𝐩𝐬 " [ PDF Guide ] 👉 𝐅𝐨𝐫 𝐌𝐨𝐫𝐞 𝐈𝐧𝐟𝐨 𝐜𝐥𝐢𝐜𝐤 𝐇𝐞𝐫𝐞: https://lnkd.in/dkYq2HMJ An infusion pump is a medical device that delivers fluids, such as #nutrients and #medications, into a patient’s body in controlled amounts. Infusion pumps are in widespread use in #clinical settings such as hospitals, nursing homes, and in the home. The increasing demand and adoption of patient engagement solutions, efforts to enhance patient-centric care by end users, growing industry consolidation through partnerships and collaborations, government initiatives and regulatory upgradation, rising healthcare expenditure, and rising prevalence of chronic diseases coupled with the increasing geriatric population. ⏹️ 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 ➢ Diabetes Management ➢ #Oncology ➢ Pain Management ➢ #Hematology ➢ #Neonatology/Pediatrics ➢ #Gastroenterology #𝐊𝐞𝐲_𝐏𝐥𝐚𝐲𝐞𝐫𝐬: Becton, Dickinson and Company, B. Braun SE, Baxter International Inc., Fresenius SE&Co. KGaA., ICU Medical, Inc., Medtronic plc, MOOG Inc., Terumo Corporation, F. Hoffmann-LA Roche Ltd, and Insulet Corporation #medicaldevice #infusionpumps #oncology #HealthcareTechnology #PatientCare #IntravenousTherapy #HealthTech #MedicationDelivery #FluidManagement #NursingTools
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