Shubham Sonu’s Post

Liquid Chromatography-Mass Spectrometry (LC-MS) is a powerful analytical technique that combines the separation capabilities of liquid chromatography with the detection and identification capabilities of mass spectrometry. However, proper sample preparation is crucial for obtaining accurate and reliable results. Let’s explore the key aspects of LC-MS sample preparation. Credit : Xenia Xu #lcms #chromatography #hplc #Analyticalchemistry #ARD #ADL #QC #pharmaceuticals #qualitu https://lnkd.in/g2QYNKwz

In the pharmaceutical industry, ensuring the safety, efficacy, and quality of a product is paramount. One key tool that plays an instrumental role in achieving this is High-Performance Liquid Chromatography (HPLC). But what exactly is HPLC, and why is it so vital in pharmaceuticals? By Dr. Dhriti Tupe, GxP Expert ® https://lnkd.in/gdTbwydx

🔥 Understanding Catabolism: The Body’s Energy Factory!🔥 Catabolism is the process by which our body breaks down complex molecules to produce energy and essential building blocks. Here’s a quick breakdown of the three stages of catabolism: 1️⃣ Breakdown of Complex Molecules: Our body first breaks down polysaccharides, lipids, and proteins into simpler units like monosaccharides, fatty acids, glycerol, and amino acids. 2️⃣ Formation of Simple Intermediates: These simpler units are further converted into key intermediates like pyruvate and acetyl CoA, releasing small amounts of energy. 3️⃣ Final Oxidation: The ultimate energy boost happens when acetyl CoA enters the Krebs cycle, generating NADH and FADH2, which are used to produce ATP—the energy currency of the body. Krebs cycle is the final common oxidative pathway for carbohydrates, fats oramino acids, through acetyl CoA. 💡 Whether you’re working on fat loss, muscle gain, or overall fitness, understanding how your body processes and uses energy can give you that extra edge! Stay strong and keep fueling your body the right way! Reference :U . Satyanarayan Biochemistry Book 💪🔥 #FitnessJourney #Catabolism #EnergyBooster 💪 💪 #fitness #fit #fitnessjourney #healthyliving #nutrition #consistency #wellness #resistancetraining #qualitysleep #healthandwellness #healthyliving #motivation #fitnessgoals

Understanding the Functions of Proteins in Our Body Did you know that proteins play a crucial role in various functions of living cells? They can be broadly categorized into two main types: static (structural) and dynamic functions. 🔹 Structural Functions: Certain proteins act like the building blocks of our body, providing structure and strength. Key examples include: - Collagen and Elastin:Found in bone matrix, the vascular system, and other organs, they are essential for maintaining the integrity of our tissues. - D-Keratin: Present in epidermal tissues, this protein is vital for skin strength and resilience. 🔹 Dynamic Functions: Dynamic proteins have a more diversified role, including: - Acting as enzymes that facilitate biochemical reactions. - Serving as hormones that regulate physiological processes. - Functioning as blood clotting factors to prevent excessive bleeding. - Acting as immunoglobulins to defend against pathogens. - Serving as membrane receptors that help in cell communication. - Acting as storage proteins and contributing to muscle contraction, respiration, and even genetic control. With such a wide range of functions, proteins are rightly considered the working horses of our cells! Let's appreciate these amazing molecules that keep our bodies functioning optimally! #proteins #body #structuralprotein

Extrapolation and Regression Study in Stability Analysis In the pharmaceutical industry, stability testing is essential for ensuring that a product maintains its quality, safety, and efficacy throughout its shelf life. Two important tools used in this process are extrapolation and regression analysis, which help predict how a drug’s stability will behave over time. Let’s explore how these techniques fit into the broader picture of stability analysis. By Dr. Dhriti Tupe, GxP Expert ® https://lnkd.in/gsAtY4h6

Applications of Polymers in Parenteral Drug Delivery Parenteral drug delivery refers to methods of administering drugs directly into the body, bypassing the digestive system, most commonly through intravenous (IV), subcutaneous (SC), or intramuscular (IM) injections. With advancements in polymer technology, polymers have become crucial in the development of sophisticated drug delivery systems, especially for prolonged and controlled drug release. https://lnkd.in/giNY-fCW

GxP, or “Good Practice” regulations, are guidelines that ensure products in industries like pharmaceuticals, biotechnology, and food production are consistently high in quality and safe for human use. The ‘x’ in GxP stands for various fields such as Good Manufacturing Practice (GMP), Good Laboratory Practice (GLP), and Good Clinical Practice (GCP). The cornerstone of any GxP-compliant system is training, as it ensures that all personnel involved are well-equipped to maintain high standards. By Dr. Dhriti Tupe, GxP Expert ® https://lnkd.in/g8P72zVw

Sterile filtration is a crucial process in pharmaceutical and biopharmaceutical manufacturing. Its main objective is to remove microorganisms from products to ensure sterility without adversely affecting the product’s quality. This process is employed widely for drug products that cannot be heat-sterilized, such as biologics and other temperature-sensitive formulations. Sterile filtration involves passing a fluid through a sterilizing-grade filter, typically rated at 0.2 or 0.22 microns, to remove microorganisms such as bacteria and fungi. https://lnkd.in/gFXpV7kk #linkedin LinkedIn #pharmaceuticals #injectableosageforms