Simon Adar’s Post

This is a modern highly intelligent way of thinking liquid biopsy presequencing and interpretation!

I did a quick overview of Element Biosciences vs. Illumina from a customer perspective. At Quantgene, we are currently preparing the rollout for Turnkey Genomics inside US hospital systems to bring testing closer to patients and fix hospital budgets. Here I share how Element Aviti compares to Novaseq and NextSeq in a direct economic comparison and it's MINDBOGGLING!

I'm quite mystified by Johannas' comparison here between Illumina NovaSeq, NextSet, and Element Biosciences Aviti. I get his point that (at least at list prices) Aviti is a better deal than NextSeq for the mid-market. But he also compares Aviti against NovaSeq and concludes that because the per Gb consumable cost is about the same, and capex is much lower for Aviti, Aviti > Novaseq 🤔 But he seems to completely ignore throughput I don't see it in his spreadsheet😳 From a quick look at the specs of the NovaSeq X, throughput max is 16Tb/run; Aviti is max is 600Gb [corrected, sorry]. So if you need serious throughput (target market for an X) you would buy an X for about $1M. To match that with Aviti you would need 16000G/600G = 27 Avitis [corrected], which would cost about $8M or more 8 times the capex of an X. What am i missing here?! Am I misunderstanding him or doing my math wrong? 🤪

The numbers of sequences we're getting are so much greater than the old days of radioactive Sanger sequencing on a gel - is there a particular throughput that we need to arrive at wherever we're trying to get? Or are we trapped in the 'when all we have is a hammer, everything's a nail' paradigm? That is - sequencing data throughput rather than the point of generating the data exercise, has become the point? We have huge Institutions which deal in sequence data and analysis - are we pursuing this paradigm because we've the infrastructure to do it? What's the answer to this question? A little information on the effects of lifestyle factors on ageing and the omics compartments and a little information on gut biome diversity with a certain lifestyle - alongside perhaps a little proof on lifestyle and biological ageing reversal would be nice - but we kinda' know what the factors which increase / decrease biological ageing will be - from thinking about the problem alongside some of the data we already have. Still I suppose it's nice to prove - but after proof - we'll be able to settle into a more measured relationship with sequence generation? Certainly fully automatable - experimentally and analytically - trivial for AI.

🚀Unify your sequencing. Stop jumping between different platforms. The new ElemBio system allows you to simplify and streamline your workflows. Sign up for virtual event #BEYOND and discover how they are pushing the boundaries of sequencing.🌟 #ElementBeyond #ElemBio

At the recent 2nd Precision Medicine in IBD Summit, it was our honor to collaborate with DNAnexus in a session that explored the transformative power of leveraging high-value multiomics data alongside an advanced analysis platform to accelerate IBD drug discovery research. Couldn't attend the session? We've got you covered! Our latest blog captures the essential takeaways from the presentation, including the impactful work Ovation and DNAnexus are doing to help researchers use multiomics data to gain faster insights into IBD. Check out the event recap on our blog: https://lnkd.in/eZBNFJYt #precisionmedicine #IBDresearch #multiomics

🇨🇭 Calling all life scientists in Switzerland: Ready to revolutionize your single-cell analysis workflow? 🇨🇭 Say goodbye to manual tissue dissociation and hello to the future with the Singulator System by S2 Genomics, exclusively distributed in Switzerland by Bucher Biotec! This benchtop powerhouse automates the entire process, delivering reproducible, rapid, and hands-off dissociation into single-cell or nuclei suspensions. ⏳ Here's what makes the Singulator a game-changer: Faster results: Ditch the tedious work – get single-cell suspensions in minutes, not hours. Unmatched precision: Single-cell resolution with minimal cell damage and stress response. Preserved RNA quality: Cold dissociation protects precious RNA for accurate downstream analysis. ❄️ Effortless workflow: Streamline your research with intuitive automation and minimal user intervention. Ready to push the boundaries of your research? Contact Bucher Biotec today to learn more about the Singulator System and how it can transform your single-cell workflows! https://lnkd.in/e6SDu_vR #bucherbiotec #lifesciences #research #singlecellanalysis #genomics #s2genomics #innovation #automation

📅 Save the Date: August 21st, 2024 🧬 Webinar: Automated Hepatocyte Counting with CellDrop 🚀 Discover the Future of Cell Counting! 🚀 Join us for an exclusive webinar hosted by DeNovix on August 21st, where we unveil our groundbreaking technology for automated hepatocyte counting using the CellDrop Automated Cell Counter. 📌 Webinar Highlights: Introduction to Machine Learning Techniques: Learn about the proprietary software algorithm that simplifies hepatocyte counting. Live Demonstration: Watch our Scientific Director, Dan Schieffer, as he showcases the Hepatocyte app in action. Interactive Q&A Session: Engage with our team of DeNovix Application Scientists and get your questions answered. 🌟 Why Attend? Experience the simplicity and reliability of our new technology. Gain insights into the innovative features of the CellDrop Automated Cell Counter. Interact live with industry experts and peers. 🔔 Register Now! Choose the session that fits your schedule: Morning Session https://lnkd.in/dhxHmPAw Afternoon Session https://lnkd.in/db5U8Dni 📣 Don’t Miss Out! Secure your spot today and be part of this exciting event. Click to register and learn more about the CellDrop Automated Cell Counter. Request a Quote: Get a quote for the CellDrop Automated Cell Counter. DeNovix - Innovating Cell Counting for the Future. #CellCounting #CellViability #Fluorescence #Hepatocytes #DeNovixWebinar

Upgrade Your Assay Designs with DNAS Application Portal v6! You asked, and we delivered! The latest version of our DNAS Application Portal is now available and packed with the most requested features. This release simplifies and improves your research, helping R&D teams like yours achieve impressive results faster than ever. Schedule demo: https://lnkd.in/gAAqJVGB Here’s what you can look forward to in the new DNAS Portal:                        1- Significant Time and Cost Savings: Streamline your primer/probe assay design processes and cut design cycle times by up to 80%, potentially saving your team millions. 2- Enhanced Capability: Boost your lab’s throughput with advanced multiplexing that allows you to handle more targets effortlessly. 3- Optimized Performance: Experience faster, more reliable results, accelerating your path from concept to market. #assaydevelopment #multiplex #pcr #qpcr #primers #probes #dnasoftware #science #biotech #researchlabs #labs #biorad #singleplex #copycount #panelplex #consensus #genome #viruses #bacteria #rna #dna

It's already September, so you know what that means - it’s nearly time to see you all again at #IMSIS2024 in Münster! Aspect Analytics has a huge presence this year with four different abstracts in the scientific program, showing different #spatialmultiomics use cases! In addition, visit our booth for live demos and attend our workshop to learn how #Weave software supports #masspecimaging #dataanalysis and #bioinformatics. Looking forward to catching up with everyone soon! #spatialbiology #spatiallipidomics #spatialmetabolomics