Spinal CSF Leak Canada Charitable Organization’s Post

Take a minute to learn about atrial fibrillation and rate control medications 👇 🎉 Kudos to the authors on this recent pub! Frick, W., Zidong Zhang, PhD, MPH, MS, Z., Rogers, L., Rojulpote, C. and Lin, C.J., 2024. Practice Patterns of Rate Control In Atrial Fibrillation and Clinical Outcomes From A Nationwide Cohort. Current Problems in Cardiology, p.102669. https://lnkd.in/gZZe4VHq

Woohoo! Our study reports the practice pattern of rate control in AFib. It may be the first report from a national cohort out of a general population in the US.#HealthServiceResearch #cardiohealth #cardiocare #AFib #PrimaryCare #HealthAnalytics #RWE #datadriven #slucare #slusom

📌 New in the Journal of Cardiovascular Electrophysiology "Left ventricular volumes and function in successful and failed His-BundLe Pacing. A comparative prospective study" by Francesco Notaristefano et al Successful HBP was superior to RVP- because of failed HBP- in preserving left ventricular function in patients with normal EF at baseline. Pacing induced cardiomyopathy developed only in the RVP group after 6-months of high pacing burden. 📷 https://lnkd.in/dwVRigVV bradley knight Hawkins Gay, MD, MPH, MSAI Giacomo Mugnai Graham Peigh #EPeeps

Ophthopedia Update:Ocular Neuromyotonia: Clinical features, Diagnosis and Outcomes: Ocular neuromyotonia is an episodic, involuntary sustained contraction of one or more extraocular muscles. It presents with intermittent diplopia often triggered by sustained gaze in the direction of action of the muscle. (1-5) It was first described clinically by Clark in 1966 (6), however, Ricker and Mertens were the first to coin the term ocular neuromyotonia in 1970. (7) Electromyographic studies have demonstrated that the spontaneous discharges from the extraocular muscles are neurogenic in origin, due to hyperactivity of the motor nerve fibers supplied by cranial nerves III, IV and VI. #Ophthalmology #Ophthotwitter #Scicomm

Quick Takes Splanchnic ablation for volume management (SAVM) involves endovascular ablation of the right greater splanchnic nerve with the goal of reducing splanchnic vasoconstriction and thus reducing filling pressures of the heart. SAVM was not shown to improve filling pressures or clinical outcomes in the results of a blinded, randomized, sham-controlled trial of 90 patients with heart failure with preserved ejection fraction (HFpEF). Subgroup analysis suggests patients with HFpEF and preserved cardiac output with exercise, chronotropic competence, preserved pulse pressure from supine to standing, and less severe diastolic dysfunction by echocardiography (E/A <2) may respond to this therapy.

All of us have pelvic pain and abdominal pain patients. Once treatable pathologies are excluded, these patients are left with little else, and suffer needlessly despite multidisciplary care including medications, behavioural therapies and physical exercises. These clinicians and researchers committed to help the visceral pain patients have an excellent, practical approach. #abdominalpain #pelvicpain #neuromodulation #interventionalpainmanagement #opioids

Future of EP to reduce the risk of Sudden Cardiac death! Please kindly check our new publication: https://lnkd.in/gPe2hucr Inherited Primary Arrhythmias Syndromes (IPAS) have been proven to possess arrhythmogenic substrates and/or arrhythmogenic activations characteristic of their respective types, which can be effectively detected through a synergistic combination of substrate-based and activation-based mapping techniques. Moreover, ablation performed at these specific sites has been conclusively shown to diminish VA recurrence and VA burdens, thereby holding promising therapeutic advantages when implemented proactively.

📖 Study findings: Topical #cryosim-1, a synthetic transient receptor potential melastatin 8 agonist, was both safe and effective in patients with #PrurigoNodularis. 👉Patients using cryosim-1 experienced significant improvements in pruritus scores and sleep quality compared to the placebo group at week 8. 👉The randomized, double-blinded, placebo-controlled clinical trial design mirrors real-world clinical practice, where prurigo nodularis is often treated with multiple agents. https://lnkd.in/gk-ZEtKn

* A really large and multinational study studied patients with DM and POAG (n=44,359) vs DM without POAG (n=4,393,300) retrospectively. * The main objective was to find if those with DM and POAG are at an increased risk of DR, and PDR. * They found precisely this i.e. those who have DM and POAG are at 2.3 times higher risk of DR compared to those without POAG. * So POAG appears to heighten the risk of DR development. This is something we should all be very aware of, and examine POAG patients with coexistent diabetes very closely for DR and PDR development. * Please share this with other ophthalmologists. * Statistical points to understand - odds ratios, risk ratios and hazard ratios are all used and reported in this paper along with their 95% confidence intervals. Full text at https://lnkd.in/dWxdK7_M