Stella Emerson’s Post

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Entrepreneur, Health Coach at Enso Complete Wellness

During perimenopause and menopause, the fluctuating and declining estrogen levels cause an accelerated shift in the balance of inflammatory signals, leading to low-grade increase in inflammation. This shift towards an increase in inflammation with declining hormones is associated with the perimenopause stage which is associated with an increased risk in inflammatory conditions. We can spend more than half our lives as postmenopausal, so, it is essential that we understand how the low ovarian hormonal state contributes to inflammation and chronic disease. Perimenopause and menopause are a result of endocrine aging. The low hormone levels contribute to inflammation. The main regulator is Estradiol, which regulates the immune system and is critical to reducing inflammation. It is a brain and cardio protector, and strengthens our bones. Estradiol is primarily produced by the ovaries, so after menopause our estradiol levels are low. The main estrogen in the body after menopause is estrone, produced primarily by adipose cells, and is pro-inflammatory.

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