The Economist’s Post

Psychiatric dieases are repeatedly being reported to be resistant to medications. A randomized controlled trial looked deep into the effect of iTBS and rTMS on treating drug-resistant PTSD sufferers (it is reported that near one third of its patients won't recover from medicines treatment at all) both of the two (iTBS and rTMS) are found to increase the remission rate. I would consider it's safe to back this very proposition that "Endless Medicines Don't Work for Depression." But just to be fair, many doctors combine drug administration with TMS. It all depends on the individual patients. Reference: Yuan H, Liu B, Li F, Jin Y, Zheng S, Ma Z, Wu Z, Chen C, Zhang L, Gu Y, Gao X, Yang Q. Effects of intermittent theta-burst transcranial magnetic stimulation on post-traumatic stress disorder symptoms: A randomized controlled trial. Psychiatry Res. 2023 Nov;329:115533. doi: 10.1016/j.psychres.2023.115533. Epub 2023 Oct 10. PMID: 37826976. #TMS #rTMS #iTBS #psychiatry #mentalhealth #medication

How can we overcome medication nonadherence in schizophrenia treatment? Join Drs. Christoph Correll and Les Citrome as they discuss the significance of nonadherence in schizophrenia care and explore solutions. These leading experts dive into the nuances of identifying nonadherence and examine innovative approaches using long-acting injectable (LAI) antipsychotics. They address the stigmas and misconceptions that prevent wider LAI adoption and share insights on presenting LAI options to patients in a way that emphasizes convenience and autonomy, thereby improving their engagement and satisfaction with treatment. Tune in to explore practical solutions for enhancing treatment consistency, with a focus on measurement-based care and identifying suitable candidates for LAI therapy. Enhance your practice today: https://ow.ly/L6bZ50QGPA6 #DispellingLAImyths #PatientCenteredCare #SchizophreniaTreatmentOption

Part V. Final. I offer these posts to offer a comprehensive overview of the antecedents of the serious emotional dysregulation, deficits in Executive function and impaired Cognition.  1. Health Promotion - Educational Materials (psychiatristsites.com) This link provides access to several illustration between Psycho-Neuro[including Vagal and Autonomic NS influences] Immuno-Endocrine- Microbiome systems and inflammatory cytokines etc. I introduced my teams and my patients to the SENSS Paradigm that I developed over the years 2. TreatmentRecommendationsforRestoringWellbeing: Managing Depression in comprehensive manner including adopting the tenets of the SENSS paradigm described in previous post. 3. What Is Mindfulness? (webmd.com) 4. Mindfulness, and Self-Regulation resources (velandymanoharmd.com) 5. The God Solution: Spirituality as a Coping Mechanism and Healing Tool for Mental Illness and Addiction | Digital Collections. 6. There are more health benefits to yoga than just being bendy (msn.com) 7. Your Guide to Lowering Your Blood Pressure with DASH (nih.gov) 8. The Mediterranean diet and health: a comprehensive overview - PubMed (nih.gov) 9. https://lnkd.in/egvT9eMv  10. How do you relieve inflammation? (webmd.com) 11. Cannabidiol (CBD): What we know and what we don't - Harvard Health 12. Psilocybin Treatment for Major Depression Effective for Up to a Year for Most Patients, Study Shows | Johns Hopkins Medicine 13.Cogntive- Behavioral asssement (velandymanoharmd.com) 14. A Common Probiotic Could Boost Brain Health in Older Adults (msn.com) 15.. Known to be heart smart whole grains may also lower the risk of Alzheimer’s in Blacks (endalznow.org) 16. Atlas of differential diagnoses: (velandymanoharmd.com). This my perspective on how the Cognitive and Behavioral aberrations demonstrated by Hon. Sen. M. McConnell in August at a press conference. I welcome your esteemed responses. Velandy Manohar, MD., Distinguished Life Fellow- Am. Psychiatric Association [APA]  Founding Member- Psychotherapy Caucus- Am Psychiatric Society, Steering Committee member until 2018. CT. Psychiatric Society: Roger Coleman Memorial Award for Exemplary devotion to patients and commitment to Quality of Care. 2010 CT. Federation of Alcoholism and Drug Abuse Counselors Bestows Honorary Membership in Recognition of his many contributions to field of Alcoholism Treatment. In-Home Addiction Treatment Institute Impact Award - In recognition of your efforts to shift the Addiction Treatment paradigm – 2019 First President, In-home Addiction Treatment, PC. First Medical Director of Aware Recovery Care. Best In Medicine- American Health Council- 2018 Founding Member- Community Resilience Collaborative-Mx. County-CT to address the consequences including Intergenerational transmission of Childhood Trauma. Member – Mx Community Coalition for Children -Mx. County, CT focusing on of SDoH factors.

Any "reliance on categorical diagnoses [for #neurodivergent types] poses significant challenges in both research and clinical settings. [...] Taking a #transdiagnostic dimensional approach [accounts] for shared underpinnings across #neurodevelopmental conditions, and [characterises] their common co-occurrence and developmental continuity [...]. Neurodevelopmental features have not been adequately considered in transdiagnostic [...] frameworks, although this would have fundamental implications for research and clinical practices..." >>Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? :: Incorporating a new neurodevelopmental spectrum?<< - Michelini, et al, 2024 doi: 10.1002/wps.21225 https://lnkd.in/e9S4BJjt

Expand your mind! The findings in this open-label nonrandomized controlled #trial suggest #efficacy and #safety of #psilocybin with #psychotherapy in BDII #depression and supports further #study of #psychedelics in this population. #mushrooms #mushroomfarming #medicalsciences #naturalhealing #nature #fungus #fungi https://lnkd.in/epB7bE29

For everyone who wanted to carry a handbag, would it be sensible to insist everyone gets a brand name? Why then, do we insist that all people who have borderline personality disorder be treated with DBT, MBT, TFP, or SFT, no matter what level of care, stage of illness, prior treatment, healthcare system, socioeconomic position, or developmental/life context? These specialized brands of treatment have innovated the design of good care for BPD, but there is not enough evidence that any brand name is superior to other manualized, informed, and structured approach to BPD delivered by providers who want to help, can be empathic or not stigmatizing towards people with the disorder, and can deliver generic principles of good care. Brands are not public health solutions and should be reserved for particular scenarios- we need more research on stepped care to understand how. There are so many people with BPD seeking support, there is room for both brand name and generic treatments. Furthermore, there are many healthcare professionals who want to be more helpful but cannot implement a brand name therapy in the work they do. Generic versions provide the basic effective ingredient of good care for BPD, for mass consumption. Good psychiatric management needs no brand, and is a generic variant of informed, structured, but flexible and pragmatic good care for BPD. But like tissue or detergent, there are many generic variants that work (e.g., SCM, GIT-PD). This Friday, I will give a talk inspired by this paper, Disruptive Innovations: Debranding Treatments for BPD at DBT Sverige, (in Sweden) virtually. Thanks to Sophie Liljedahl for the invitation and 90 minutes to get through my overflowing deck of animated slides... #goodpsychiatricmanagement #GPM

Development of psychiatric common data model (P-CDM) leveraging psychiatric scales #OHDSISocialShowcase Lead: Dong Yun Lee Team: Chungsoo Kim, Rae Woong Park Background: The limitations of a categorical diagnostic system in neuropsychiatric illness have become increasingly apparent. A diagnostic category such as depression captures a large heterogeneous range of presentations. By categorizing various symptoms with only a diagnosis code, there is a loss of information. To compensate for these issues, various psychiatric scales have been introduced and are used in practice. However, the common data model does not include psychiatric scales. Therefore, we aimed to develop a common data model for psychiatry that utilizes the psychiatric scale. Learn More: https://lnkd.in/eU5z8dCv #JoinTheJourney

Exciting news in the field of mental health: NMRA-266, an innovative treatment for schizophrenia, has been greenlit for phase 1 clinical trials by the FDA. Developed by the sharp minds at Vanderbilt University's WCNDD, this compound is a beacon of hope for approximately 3.7 million U.S. adults grappling with this challenging disorder. 🧠✨ Schizophrenia's impact on cognitive and psychological functioning can be profound, and current treatments often bring a host of unwelcome side effects. Enter NMRA-266, which preclinical studies suggest could offer symptom relief without these drawbacks by targeting the M4 receptor to regulate dopamine levels. 👁️🗨️ This milestone underscores the power of collaboration between academia and the industry. Vanderbilt's partnership with Neumora Therapeutics Inc. exemplifies how such alliances can propel scientific breakthroughs from the lab bench to clinical trials. 🤝 As a professional committed to staying abreast of transformative healthcare developments, I'm inspired by the prospect of NMRA-266 offering a new therapeutic avenue for those affected by neuropsychiatric disorders. The potential of NMRA-266 to revolutionize treatment extends beyond schizophrenia, potentially reshaping the landscape of mental health care. 🌐 As the clinical trial unfolds, let's keep our eyes on this promising compound. The implications for mental health could be profound. I welcome your thoughts on this pioneering venture. Could NMRA-266 be the dawn of a new era in neuropsychiatric treatment? Share your views below. #MentalHealthInnovation #SchizophreniaResearch #ClinicalTrials #HealthcareProgress 🗣️💡 Original article: https://lnkd.in/diezSUSw

My latest (6/5/24) YouTube, "A Psychiatrist Looks at Road Rage," introduces several psychological concepts as they apply to this common problem: object relations theory, splitting, displacement, and "the fundamental attribution error." As always, I welcome your comments and feedback, either here or on YouTube itself. #psychotherapy #psychiatry