Today we announced 80% of patients in our na-SPMS program saw a qualitative improvement in neuroimaging at 6 months of treatment with intranasal foralumab. $TLSA #MultipleSclerosis #SPMS #MS #PET Tarun Singhal, MBBS, MD https://lnkd.in/gi8x5A3e
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A #NPi #Pupillometry study found that patients with even one left and right #NPi difference of ≥0.7 had higher discharge modified Rankin Scores and worse outcome. This study confirms NPi difference of ≥0.7 as an abnormal threshold, even within the normal NPi range ≥3.0. READ MORE: https://ow.ly/2rlw50Qcgsc #NPiDiff #critcaremed #neuronurses #neuromonitoring
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In this video from ISET 2024, Ramon Varcoe, MBBS, MS, PhD, MMed (ClinEpi), discusses his presentation on the #LIFE-BTK study, which assessed the safety and effectiveness of the Abbott Esprit BTK scaffold, with an emphasis on the differences between patients with Rutherford Category 4 and 5. https://okt.to/I0HsYM
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𝐅𝐢𝐫𝐬𝐭 𝐈𝐧𝐭𝐞𝐫𝐢𝐦 𝐑𝐞𝐬𝐮𝐥𝐭𝐬 𝐨𝐟 𝐭𝐡𝐞 𝐄𝐮𝐫𝐨𝐩𝐞𝐚𝐧 𝐌𝐮𝐥𝐭𝐢𝐜𝐞𝐧𝐭𝐞𝐫 𝐍𝐄𝐎𝐒 𝐒𝐭𝐮𝐝𝐲 E-vita® Open Neo Post Market Clinical Follow-Up Study 𝐈𝐧𝐭𝐫𝐚-𝐎𝐩𝐞𝐫𝐚𝐭𝐢𝐯𝐞 𝐃𝐚𝐭𝐚 • Total procedure time: 414.2 ± 98.6 min • Mean Cardiopulmonary bypass time: 233.2 min [113.0;515.0] • Mean aortic cross-clamp time: 118.5 min [29.0;279.0] • Mean visceral arrest time: 47.8 min [2.0;109.0] • Abnormal bleeding issues with the E-vita® Open Neo for 9.1% patients, but no new adverse event occurred due to the difficulties Learn more about the NEOS study: https://bit.ly/49dkUCM #EvitaOpenNeo #FollowUpStudy #ArchSolutions
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This paper from the Journal of Wound Care (JWC), seeks to evaluate the effectiveness of wound bed preparation by #LarvalTherapy (Maggot Debridement Therapy, MDT) in patients with critical limb ischaemia (CLI) who had undergone mid-foot amputation. ➡ The efficacy of MDT with favourable wound bed preparation was shown in CLI patients based on effective debridement and granulation formation by maggots, avoiding the loss of their heels. ➡ MDT is considered a valid adjuvant treatment strategy for patients with CLI after revascularisation treatment is conducted. ➡ More favourable wound bed preparation and successful graft take were achieved in the MDT group, suggesting the effectiveness of MDT for wound healing in CLI patients. Read in full: https://loom.ly/qOB3pVc
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Clinical Resource Nurse at Sheikh Shakhbout Medical City/Nurse Clinical Educator for Adult Critical Care Units at American University of Beirut Medical Center
Time to reflect on managementof 33% of our ICU patients experiencing #shock or #circulatory #collapse ! A 55 yrs old 84 kg male patient arrives to ED with weakeness and confusion; admitted 4 weeks earlier c/o sepsis due to cellulitis. Patient transferred to #ICU for further management as recurrent #sepsis. In ICU BP 78/42, MAP 54, SpO2 82%. Intubated ventilated, lactate 9, CVP 8mmHg. Question: what is the best measure to optimize #tissue #perfusion? #Fluids vs. #vasoactive or #inotropic support? To navigate though your care always remember: Reliable early predictors of pressure status and perfusion response are imperative for caring for patients who are #hemodynamically #unstable. Although traditional static hemodynamic variables (CVP) are helpful, #advanced #variables of #hypotension #prediction allow safer more precise optimization of tissue perfusion. #Fluid #resuscitation without a step-wise process of measuring response is detrimental. Using #hemodynamic #optimization #algorithm can help personalize care and deliver accurate #EBP treatment plan.
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Clinical & Sales Lead | Strong clinical, sales & marketing expertise | Sports Scientist | Driven, resourceful problem-solver in a fast-paced & constantly evolving scale-up environment
Transcatheter edge-to-edge repair (TEER) is a standard care procedure for many years now. Still, the prognostic benefits of TEER remain unclear in patients with atrial functional mitral regurgitation (AFMR). This recent investigation aimed for clinical outcomes in TEER for patients with AFMR Check out the full paper here: #teer #edgetoedge #afmr #mitralvalverepair
Outcomes of transcatheter edge-to-edge repair for atrial functional mitral regurgitation
eurointervention.pcronline.com
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Metaphase: Metaphase is a stage in cell division, specifically in mitosis and meiosis, where the chromosomes align at the cell's equator. During metaphase, the chromosomes become attached to the spindle fibers and are arranged in a single plane called the metaphase plate. This alignment ensures that each daughter cell receives the correct number of chromosomes during cell division. Don’t hesitate: Our team of Exam Counsellors is here to assist you +44 7307 237595 Sincerely & our dedication is to serve you, Med Recalls #MRCSstudents #MRCSExam #MedicalEducation #patientcare #medicalawareness #Medicine#HealthcareEducation #Doctors #medicalprofessionals #RCOG #MRCOG1 #MRCOG2 #MRCOG3 #oetpreparation #plabexam #healthcareprofessionals #medacademy #MRCP #MRCS #MRCPI #EBCOG #FCPS #MCPS #MRCPCH #FCPS #PLABWebinar #KeepPushing #NeverBackDown #MedicalDreams #medrecalls
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BRASH is defined as a combination of bradycardia, renal failure, AV nodal blockade, shock, and hyperkalemia. Furthermore, “the BRASH acronym is used to describe a syndrome where the synergistic effects of AV nodal blockers and renal impairment lead to severe bradycardia and hyperkalemia” (NCBI, 2023). BRASH is due to a positive feedback loop. Synergism between AV blockers and hyperkalemia cause a drop in heart rate which drops our cardiac output and thus our BP. This causes hypoperfusion to our kidneys thus causing renal injury/failure. This decreases the Glomerular Filtration Rate (GFR) which in turn decreases the amount of AV blockers to be excreted and potassium to be excreted. Build up of beta blockers cause the cells to secrete more K+ which increases serum potassium. Build up of potassium once again combined with the AV blocker meds and the cycle repeats. It should be mentioned that ACEi/ARBs decrease aldosterone concentrations which decreases the amount of potassium being excreted. Aldosterone causes reabsorption of sodium (and the water follows) and potassium should be excreted. Low levels prevent potassium from being excreted so they build up. BRASH syndrome is typically found in the elderly patient that is taking cardiovascular medications and suffering from dehydration. It is important to note that the typical ECG findings associated with isolated hyperkalemia (e.g peaked T waves, wide QRS) may be absent. Additionally, the bradycardia seen may be out of proportion to the other ECG findings typically found with hyperkalemia. Key components of therapy include volume management, treatment of bradycardia, treatment of hyperkalemia, and treatment of any underlying cause(s). **Disclaimer: this is a reference. Please use your own protocols* 📚Sources: https://lnkd.in/g94p6AvF. https://lnkd.in/g_xXzi7N. https://lnkd.in/guvT49_5 #FOAMed #nurse #paramedic #ems #medical #meded #medicaleducation #criticalcare #emergencymedicine #physician
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Check out our summary on recommendations for the use of asparaginase-containing regimens in obese adult patients with ALL and the associated outcomes 👉 https://loom.ly/GUj3-D0. #allsm #leusm #MedEducation
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Central retinal vein occlusion (CRVO) is a condition where the main vein in the retina becomes blocked, leading to impaired blood flow. It can cause sudden, painless vision loss. CRVO is categorized as non-ischemic (partial blockage) or ischemic (severe blockage). Underlying factors may include atherosclerosis or vascular conditions. Treatment involves managing contributing factors and addressing complications such as macular edema. Seeking prompt medical attention is crucial for diagnosis and appropriate intervention. Don't hesitate: Our team of Exam Counsellors is here to assist you +44 7307 237595 Follow us on Instagram for updates: https://lnkd.in/dFtR6dvz ?igshid=OGQ5ZDc2ODk2ZA Connect for professional networking: https://lnkd.in/dszjwdat Like us on Facebook to stay in touch: https://lnkd.in/enk8qU2? id=100044112052155&mibextid=LQQJ4d Sincerely & our dedication to serving you, Med Instutors #MRCSstudents #MRCSExam #MedicalEducation #patientcare #medicalawareness #Medicine #HealthcareEducation #Doctors #MedicalProfessionals#RCOG #MRCOG1 #MRCOG2 #MRCOG3 #oetpreparation#PLABexam #healthcareprofessionals #medacademy #MRCP #MRCS #MRCPI #EBCOG #FCPS #MCPS #MRCPCH #FCPS #MRCOG3 #MedicalEducation #medinstutors
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