Transasia Bio-Medicals Ltd.’s Post

Voluntary blood donation forms the cornerstone of a secure and reliable blood supply. To ensure the utmost safety of donated blood, it is crucial to screen for transfusion-transmissible infections (TTIs) such as HIV, Hepatitis B (HBV), Hepatitis C (HCV), Syphilis, and Malaria. Erba Transasia's screening reagent kits are pivotal in this process, significantly reducing the risk of these infections being passed on through blood transfusion. These kits utilize 4th generation immunoassays for simultaneously detecting antigen and antibodies against TTIs (for HIV and HCV). These advanced kits provide accurate and timely results, enhancing overall safety and reliability during blood transfusion. By incorporating Erba Transasia's Blood Banking ELISAs into the screening process, blood banks and healthcare facilities can ensure a higher standard of care and safety for patients needing blood transfusion. Learn more at https://zurl.co/U1hH or reach out to us at 7400058929. #IAmTransasia #WeAreErba #clinicalanalysis #laboratoryanalysis #TTIdetection #pathology #IVD #bloodbankserology #bloodsafety #safebloodtransfusion #ELISA

Ensuring a secure blood supply is critically dependent on voluntary blood donation. Our Erba Lisa Blood Banking reagent kits ensure blood safety by significantly reducing the risk of TTIs such as HIV, HBV, HCV, Syphilis, and Malaria. These kits provide accurate and reliable results, ensuring every unit of donated blood is safe for transfusion. Erba Transasia’s Lisa XL, is a groundbreaking Made-in-India 6-plate ELISA processor. This high-throughput analyzer, with an impressive capacity to process up to 576 tests, is equipped with advanced features, making it an ideal choice for screening transfusion-transmitted infections (TTIs) in blood banks. With these cutting-edge solutions, blood banks can confidently safeguard the health of recipients and donors alike. Learn more at https://zurl.co/Zuxx and https://zurl.co/aQ71 or contact our team at 7400058929. #IAmTransasia #WeAreErba #TTI #clinicalanalysis #laboratoryanalysis #TTIdetection #pathology #IVD #bloodbankserology #bloodsafety #safebloodtransfusion #ELISA

Ensuring a secure blood supply is critically dependent on voluntary blood donation. Our Erba Lisa Blood Banking reagent kits ensure blood safety by significantly reducing the risk of TTIs such as HIV, HBV, HCV, Syphilis, and Malaria. These kits provide accurate and reliable results, ensuring every unit of donated blood is safe for transfusion. Erba Transasia’s Lisa XL, is a groundbreaking Made-in-India 6-plate ELISA processor. This high-throughput analyzer, with an impressive capacity to process up to 576 tests, is equipped with advanced features, making it an ideal choice for screening transfusion-transmitted infections (TTIs) in blood banks. With these cutting-edge solutions, blood banks can confidently safeguard the health of recipients and donors alike. Learn more at https://zurl.co/Zuxx and https://zurl.co/aQ71 or contact our team at 7400058929. #IAmTransasia #WeAreErba #TTI #clinicalanalysis #laboratoryanalysis #TTIdetection #pathology #IVD #bloodbankserology #bloodsafety #safebloodtransfusion #ELISA

"A Non-Integer Variable Order Mathematical Model of Human Immunodeficiency Virus and Malaria Co-infection with Time Delay" "The link of the full paper is in the 1st comment" Abstract: Te purpose of this paper is to propose a variable fractional-order model with a constant time delay of the co-infection of HIV/AIDS and malaria. Te proposed model describes the interaction between HIV/AIDS and malaria. This model is presented by using variable fractional-order derivative which is an extension of the constant fractional-order derivative to explain a certain pattern in the development of infection of several patients. Te presented model has been solved numerically via the predictor-corrector scheme. Te local and global stability conditions of the disease-free equilibrium are investigated. Also, numerical simulations are presented for different variable fractional-order derivatives in Caputo sense.

📢 Medicines and Healthcare products Regulatory Agency approved the first generic raltegravir medicines to treat adult and paediatric patients infected by HIV Raltegravir works by stopping HIV-produced enzyme HIV integrase (which enables multiplication of the virus in cells within the body) from working. When used with other medicines, it may reduce the amount of HIV in the patient’s blood and increase the patient’s CD4-cell count (a type of white blood cell that plays an important role in maintaining a healthy immune system). Reducing the amount of HIV in the blood may improve the functioning of the immune system, meaning the body may fight infection better. MHRA Deputy Director of Innovative Medicines, Shirley Hopper, said: "“Ensuring timely access to generic medicines is a key priority for us. “Appropriate data have been provided to assure us that these medicines are the same as, and considered interchangeable with an already licensed reference medicine, called Isentress. “As with all products, we will keep the safety of raltegravir under close review.’’ Find out more ➡️ https://bit.ly/3LxQJwc

Here is an article we have just published in BMC Infectious Diseases "Drug-induced hepatotoxicity and association with slow acetylation variants NAT2*5 and NAT2*6 in Cameroonian patients with tuberculosis and HIV co-infection" https://lnkd.in/ekRtg5X9

A (typically) excellent study from the South African Blood Service, available on Open Access, so I don't need to comment beyond adding that, thanks to a public commitment to screen blood donations with the most sensitive technology available, the risk HIV transmission through blood transfusion is very low in South Africa. Further studies of this type are needed in the other countries of Sub-Saharan Africa, to guide resource allocation for blood services. The first duty of a blood service is to provide adequate supplies of safe blood for transfusion, over and above any subsequent progression to plasma fractionation etc. I draw attention to the indications for blood transfusion provided by the authors, which vary significantly from those in most Western countries. These should be fundamental in formulating blood policy. I bow my head to the SANBS, which provides a first class service in difficult conditions. https://lnkd.in/g9mVT-79

📃Scientific paper: Human Immunodeficiency Virus-associated Immune Complex Kidney Disease Progressing to End-stage Kidney Disease Abstract: A 58-year-old man with human immunodeficiency virus (HIV) infection presented with a week-long history of gross hematuria, nephrotic proteinuria, and acute kidney injury. The patient was non-adherent with combination antiretroviral therapy. A kidney biopsy showed cellular crescents with disruption of Bowman's capsule, C3-dominant immune complex deposition, consistent with HIV-associated immune complex kidney disease (HIVICK). During the course, his worsening kidney function warranted initiation of hemodialysis. This case highlights the fact that HIV patients are at an increased risk of developing HIVICK, especially in the setting of non-adherence. A greater understanding of HIVICK among HIV patients should promote additional investigation into its etiology and viable treatments. Continued on ES/IODE ➡️ https://etcse.fr/MVz ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

Dysplastic neutrophils in an HIV-positive woman 🔬 A routine blood count on an 18-year-old HIV-positive African woman showed anemia and thrombocytopenia (Hb 55 g/l, platelet count 10 × 109/l). The blood film showed changes reflecting recurrent infection including increased background staining, rouleaux formation and reactive changes in lymphocytes. In addition, neutrophils showed striking dysplastic features, which included : - Detached nuclear fragments (top images) - Acquired Pelger–Huët anomaly (bottom left) - Chromatin clumping - Neutrophils with strangely shaped nuclei and a high nucleocytoplasmic ratio (bottom right) Dysplastic changes in neutrophils are common in patients with AIDS and can be the feature that suggests the possibility of HIV infection. The presence of detached nuclear fragments in neutrophils is particularly suggestive. The range of changes seen differ from those that are usual in myelodysplastic syndromes. Hypogranularity is less common whereas bizarrely shaped nuclei and a high nucleocytoplasmic ratio in mature cells are more common. Detached nuclear fragments can occur in myelodysplastic syndromes but they are quite uncommon, whereas they are characteristic of HIV infection. Reference 📖 Bain BJ (2008) Dysplastic neutrophils in an HIV-positive woman. Am J Hematol, 83, 738.

📢 We've approved the first generic raltegravir medicines to treat adult and paediatric patients infected by HIV Raltegravir works by stopping HIV-produced enzyme HIV integrase (which enables multiplication of the virus in cells within the body) from working. When used with other medicines, it may reduce the amount of HIV in the patient’s blood and increase the patient’s CD4-cell count (a type of white blood cell that plays an important role in maintaining a healthy immune system). Reducing the amount of HIV in the blood may improve the functioning of the immune system, meaning the body may fight infection better. Our Deputy Director of Innovative Medicines, Shirley Hopper, said: "Ensuring timely access to generic medicines is a key priority for us. “Appropriate data have been provided to assure us that these medicines are the same as, and considered interchangeable with an already licensed reference medicine, called Isentress. “As with all products, we will keep the safety of raltegravir under close review.’’ Find out more ➡️ https://bit.ly/3LxQJwc