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Due to system maintenance, all GenomeWeb sites (GenomeWeb, 360Dx, and Precision Medicine Online) are open access through Sunday! We welcome everyone to explore our excellent journalism with no restrictions for a limited time! Here's a sampling of our in-depth reporting this year in Precision Medicine Online for subscribers: Sickle Cell Gene Therapy Fertility Risks Spur Calls for Changes Allowing Industry Support Services https://lnkd.in/emk-n9ZH by Jessica Kim Cohen 'The Lead That Starts the Avalanche': Second Solid Tumor Cell Therapy Approval Energizes the Field https://lnkd.in/eYyPZdXp by Caroline Hopkins Legaspi Molecular Tumor Boards Improve Precision Medicine Access, but Increasing Patient Reach a Challenge https://lnkd.in/e9yUCBA4 by Alison Kanski AI Could Reshape Precision Medicine, but First, Doctors Have to Trust It  https://lnkd.in/em5sXaEW by Catherine Shaffer

#Gene and cell therapies are gaining interest as therapeutic strategies for neurological and psychiatric disorders. #Positron emission tomography (PET) has been established as a uniquely powerful modality for brain molecular imaging in vivo. #PET probes are potentially useful to confirm the success of gene therapy or cell transduction without the need for brain biopsy or necroscopy. Hope you enjoy reading our latest perspective in ACS-J Med Chem 📖 #NIMH #NIH https://lnkd.in/e6YFt-9v

Stanford Medicine Children's #Health has recently introduced a gene therapy approved by the #FDA for X linked adrenoleukodystrophy (ALD) an severe neurological condition affecting children. The groundbreaking stem cell-based therapy is a more efficient option compared to the conventional stem cell transplantation. The treatment involves altering the patient's #stemcells to stop the advancement of #ALD, eliminating the risks linked to using donor cells like graft versus host disease (GVHD). What were the results of the #stemcelltherapy? It has helped the two children named "Ivan" and "Israel" are living normal kids life. They even indulge in various kid pastimes with their younger sister. Discover details about this transformative therapy. https://lnkd.in/g3WMSPzd

Explore adherent cell culture research through our article: “Adherent Cell Culture Research: From Start-Up to Scale-Up.” Discover how this research has propelled advances in modern medicine and supported the development of interventions in regenerative medicine, immuno-oncology, gene therapy, and tissue engineering. Learn about the challenges and solutions in scaling up cell production, from establishing efficient protocols to transitioning to larger vessels. Don’t miss out on this insightful read! https://lnkd.in/gHtW2GEe #CellCulture #Research #ScaleUp #RegenerativeMedicine #ImmunoOncology #GeneTherapy #TissueEngineering

🌍 The Future of Regenerative Medicine The regenerative medicine market is growing at an unprecedented CAGR of 25.1%, projected to reach $49 billion by 2028. Innovations like stem cell therapy, gene editing, and immunotherapy are transforming patient care. At Turacoz, we’re enabling this revolution through scientific communication, real-world evidence generation, and strategic market access support. Let’s shape the future together! #RegenerativeMedicine #HealthcareInnovation #Turacoz

In our lab, we're advancing stem cell and marrow transplant therapies through cell therapy, cryopreservation, and gene research. By combining human blood samples with cutting-edge machines, we refine the conditions for successful treatments. We collaborate with other scientists to improve procedures and conduct experiments that drive breakthroughs in medical science. Our work is supported by Biological Safety Cabinets (BSCs), which create sterile environments to protect both researchers and sensitive samples, ensuring contamination-free conditions for precise, safe research. We’re excited to keep pushing the boundaries of cellular medicine to improve patient outcomes! #TechTuesday #StemCells #MarrowTransplant #GeneResearch #CellTherapy #MedicalAdvancements #FutureOfMedicine #MedicalResearch #CellProcessing #Cryopreservation

🧠 Is it possible to undo cell death in the brain? And can neural functions that are lost as a result of brain damage be regained? Tang et al (2021) explored this topic in their paper Restoration of Visual Function and Cortical Connectivity After Ischemic Injury Through NeuroD1-Mediated Gene Therapy. The main findings from the study concern the innovative gene therapy approach for restoring visual function and cortical connectivity after ischemic brain injury. Researchers used NeuroD1-mediated gene therapy to convert non-functional glial cells in the brain into neurons. Researchers were able to show that nonfunctional glial cells surrounding damaged tissue in the primary visual cortex could be converted into neurons. They then found, using CRACM, that these reprogrammed cells were well integrated into the visual cortex. Finally, using calcium imaging techniques, they found that the reprogrammed cells took on functional properties of primary visual cortex neurons. Together, these findings represent a fascinating and elegant approach to traumatic brain injury therapy. --- Mightex's Polygon patterned light illuminator was used to illuminate individual pixels in the visual cortex in a random order, in this research. If you would like to learn more about the tools that Mightex has available to support CRACM techniques, take a look here. > https://lnkd.in/eGFDv2ME

“Gene-Therapy simplied for curious minds” Gene therapy is like sending a repair crew into your body to fix broken genes. Scientists use specially designed viruses to carry healthy genes into your body, helping it function properly. Excitingly, over 2,500 clinical trials worldwide are showing promise, targeting diseases like inherited blindness and certain cancers. Breakthroughs include Luxturna for inherited blindness and CAR-T cell therapy for leukemia and lymphoma. In the future, gene therapy could revolutionize medicine, offering potential cures for genetic diseases and improving lives globally. Would you like to add anything? Lets connect! Jiten P. CEO and CSO OmniBRx Biotechnologies Inc. USA #genetherapy #celltherapy #CART #vectors #scientists

The recognition of miRNA’s role in gene regulation and its profound impact on aging, cell regulation, and senescence is a major step forward for the scientific community. This discovery brings us closer to understanding the mechanisms behind cellular aging and opens new doors for innovative therapies. As someone deeply involved in the field of stem cells and regenerative medicine, I believe this is just the beginning. Next year, we can expect even more focus on aging-related studies, and stem cell research especially iPSC will undoubtedly play a pivotal role. The intersection of miRNA, stem cells, and aging holds immense potential for revolutionizing treatments for age-related diseases and conditions. #NobelPrize #AgingResearch #StemCells #miRNA #RegenerativeMedicine

If you're attending the 6th Annual Gene Therapy for CNS Summit in Boston, make sure attend our CEO Josefina Nilssons presentation at 10 am EST #TODAY! Or find her at the conference to talk about our GMP-certified TEM services, quality control analyses of nanoparticles, or simply to say hello. This year’s summit focuses on breaking barriers in gene therapy for neurological conditions, from novel AAV performance to improving biodistribution and translating these therapies from preclinical models to real-world clinical success. As a company committed to advancing treatments and we’re thrilled to be part of this conversation with leading experts in translational research, R&D, and clinical innovation. #GeneTherapy #Neurology #Innovation #Leadership #TEM #QuTEM