UNOMR’s Post

🖋 Publication Alert for UNOMR in our Startup Track 🚀 🔎 🚀 "Aptamer-Functionalized Interface Nanopores Enable Amino Acid-Specific Peptide Detection" 📘💡 Researchers at UNOMR, the winner of our Startup Track grant, have taken a giant leap towards single-molecule proteomics. Cofounders Julian Hengsteler & Til Schlotter, in collaboration with Nako Nakatsuka, Ph.D., published this exciting paper demonstrating their technology's ability to target specific amino-acids on peptides with their aptamer-functionalized interface nanopores. 🔍 Key Breakthroughs: 🐢 Slowing down peptide movement to enhance resolution: By slowing down peptide translocation events, their integrated amino acid-specific DNA aptamers ensure single amino acid resolution is achievable. 🎯 Reducing variability in nanopore size: Their innovative approach addresses the variability in solid-state nanopore size & shape, introducing dynamically tunable pores for enhanced sensing accuracy and reproducibility. 🌐 With the possible integration of serial nanopores and additional amino acid-specific aptamers, full #proteinsequencing could be possible! Keep an eye on this space, setting the stage for monumental advancements in diagnostic and therapeutic application Read about it here ➡ https://lnkd.in/evjrbtcH #swissbiotech #proteomics #nanopore Student Biolab Zurich, ETH Entrepreneurship; Renate Hahn; Flavio Rump; Joseph Iwasyk; Justyna Stefaniak; Alexandra Siffert; Cameron Boggon