🎉 Celebrate, learn, and connect with Waters at HPLC 2024. Don’t miss our Welcome Reception, Lunch Session, Oral and Poster presentations, and Awards ceremonies, including the presentation of the 2024 Uwe D. Neue Award to Dr. Miroslav Janco. Be the first to see the line-up of Waters events throughout the week here: https://bit.ly/3KCLXgA
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Last call to register https://lnkd.in/gs33x28G for the upcoming preparative chromatography webinar! Do you want to streamline and enhance your purification processes? Search no more! Dr. Birke Götz from BUCHI is teaming up with Holger Gumm, Managing Director, Sepiatec GmbH, and Ron Magboo, Senior Principal Investigator at Incyte, for our webinar “How to switch from prep HPLC to prep SFC?” 📅Date: May 2nd 🕚Time: 11 am CET ⌛ Length: 45 minutes During the webinar, our panel of experts will guide you through the process of smoothly transitioning from prep HPLC to SFC, focusing on the following topics: • A basic theoretical explanation of prep SFC • A comparative analysis of prep HPLC and SFC techniques • SFC benefits and method development • Application examples Grab one of our last spots and delve into the secrets of prep SFC!!
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🤔Curious how Charged Aerosol Detectors can compliment a wide range of HPLC methods and workflows? Tune in live or on-demand ➡️ http://spr.ly/6049ZOEmP #chromatography #hplc
🔬Join this live HPLC-CAD webinar starring speakers from Amgen 🗓️ Date: Thursday, April 4, 2024 🕓 Time: 15:00 BST, 16:00 CEST, 9 AM CDT, 19:00 GST In recent years, the use of quantitative liquid chromatography (LC) coupled charged aerosol detection (CAD) for UV-absorbing analytes in multicomponent mixtures has surged across various industries. But what sets CAD apart from other detection methods, and how can you optimize its parameters for successful analytical method development? Imad Haidar Ahmad, Ph.D., and Wes Barnhart from Amgen will address these questions and more during our live webinar. Register now to attend the live session or to receive the link to the recording » http://spr.ly/6049ZOEmP
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LC business owner with a passion to drive the development and adoption of new chromatographic solutions
If you'd like to learn about Charged Aerosol Detectors and how these can compliment a wide range of liquid chromatography methods and workflows, this event is ideal; check it out!
🔬Join this live HPLC-CAD webinar starring speakers from Amgen 🗓️ Date: Thursday, April 4, 2024 🕓 Time: 15:00 BST, 16:00 CEST, 9 AM CDT, 19:00 GST In recent years, the use of quantitative liquid chromatography (LC) coupled charged aerosol detection (CAD) for UV-absorbing analytes in multicomponent mixtures has surged across various industries. But what sets CAD apart from other detection methods, and how can you optimize its parameters for successful analytical method development? Imad Haidar Ahmad, Ph.D., and Wes Barnhart from Amgen will address these questions and more during our live webinar. Register now to attend the live session or to receive the link to the recording » http://spr.ly/6049ZOEmP
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March 27 Webinar Announcement: Biotherapeutic Characterization 10 am CET Session: https://lnkd.in/ewsrbH9g 4 pm CET Session: https://lnkd.in/eH2QAJYk Our in house experts, Cory E. Muraco and Anders Fridström, will be highlighting several new reference materials that will be launching soon and outlining some cutting-edge approaches in characterizing these compounds of interest. Also, more about the new 1.5 mm I.D. BIOshell columns...and another new column highlighted here (tune in so you don't miss it!).
Mastering Biotherapeutic Analysis with Expert Insights on Reference Materials and HPLC Method Development_AM
event.on24.com
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When it comes to flow cytometry workflows, a study conducted by our R&D team found that up to 80% of time spent preparing cocktails can be avoided. The study also showed that 25% of lab reagents are wasted due to errors, expiration, spillage, and internal QC requirements. What’s more, manually preparing laboratory-developed tests (LDTs) can create intra-lab variability. Have you calculated the cost of your LDT? Our handbook helps you create a cost-benefit analysis for liquid LDTs vs our antibody panels. Download it here: https://becls.co/3QOWgCB
Have you calculated the cost of your LDT?
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Dive deep into the intricacies of In Vitro-In Vivo Correlation (IVIVC) for complex administration methods beyond traditional routes. Learn how to establish correlations for transdermal patches with delayed absorption using Phoenix IVIVC software. Discover how Bioequivalence (BE) waivers can help optimize manufacturing processes and reduce costs. Date: August 28 Time: 10 AM ET Speaker: Christopher Mehl Don't miss this invaluable session for drug formulation scientists and manufacturers. https://ow.ly/oRtQ50SFtlw
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Just when you think we know all about causes of polysorbate degradation, Jean-Rene and his team show us another thing about which to worry. Read this paper!
Our last paper on Polysorbate oxidation. A very surprising effect was observed: when the DP was kept in the filling set PS80 during filling stops, the oxidation kinetics at 2-8C was dramatically accelerated ! Read the paper to know why. congrats to our main authors Heloise Audat and Laetitia Poumarede !
Publication: Impact of tubing material on stability and filling accuracy of biologic drug product
sciencedirect.com
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This week I read Gilles Ouvry’s insightful post on azetidine amides. (If you’re a med chemist, Gilles Ouvry is a MUST-follow for his brilliant med chem insights and infographics). He points out that azetidine amides are unique because they can have a different SAR than other tertiary amides due to their unique torsional profile. For example - when a benzamide nitrogen is N,N-disubstituted, steric effects twist the amide out of plane with the benazmide. Azetidine amides instead tend to behave more like mono-substituted amides while not having an N-H donor. (See Gilles' write-up here: https://lnkd.in/gxerU_Qj) With the Drug Hunter substructure search, I was surprised to find numerous examples of azetidine amides being applied in clinical candidates through Ph. III, even though there’s only one approved drug with this motif (cobimetinib). You can request a demo of Drug Hunter and the Structure Search feature at the link below: https://lnkd.in/gSK-zSwV
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