Cancer Gene Therapy Market Size, Share & Trends Analysis Report by 2032
Shivani Mhatre
𝗛𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 | 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗲𝘂𝘁𝗶𝗰𝗮𝗹𝘀 | 𝗠𝗲𝗱𝗶𝗰𝗮𝗹 𝗗𝗲𝘃𝗶𝗰𝗲𝘀 & 𝗦𝘂𝗽𝗽𝗹𝗶𝗲𝘀 | 𝗗𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝘀 𝗮𝗻𝗱 𝗕𝗶𝗼𝘁𝗲𝗰𝗵 | 𝗟𝗶𝗳𝗲 𝗦𝗰𝗶𝗲𝗻𝗰𝗲𝘀
As per the report from nova one advisor, the global cancer gene therapy market is valued at USD 2.45 billion in 2023 and is projected to reach a value of USD 12.75 billion by 2032 at a CAGR (Compound Annual Growth Rate) of 20.1% between 2023 and 2032
Key Pointers:
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The growth of the market is attributed to factors such as the growing demand for gene therapy and an increased incidence of cancer cases across the globe. Moreover, with the emergence of advancements in gene therapy, it is anticipated to become an effective alternative exercise for the treatment of all types of cancers and neoplastic disorders. For instance, in March 2021, the U.S. FDA approved Abecma (idecabtagene vicleucel), a cell-based gene therapy to be used for the treatment of patients with multiple myeloma who were incapable to respond to the initial lines of therapy.
The COVID-19 pandemic outbreak had posed challenges to the continuance of cell and gene therapy research exercises in terms of mobilization of resources and manufacturing capacities. Nevertheless, some cancer gene therapies have made it to secure regenerative medicine advanced therapy (RMAT) and priority medicine (PRIME) designation. For instance, in October 2020, Orca-T (by Orca Bio) was granted RMAT to be used for subjects with blood cancers. Similarly, ADP-A2M4, transduced CD4+ and CD8+ cells (by Adaptimmune) were granted PRIME to be used for the treatment of HLA-A positive subjects with metastatic synovial sarcoma.
The increasing prevalence of cancer cases is expected to create a high demand for novel therapeutic drugs that could be effective for cancer treatment. The emerging role of immunotherapy in cancer treatment has rendered the focus of conventional gene therapies to target the immune system to yield better remissions for subjects with cancers at an advanced stage. For instance, in September 2022, the Hadassah Cancer Research Institute (HCRI), Jerusalem declared that it will lead the CancerRNA, a global forum working towards development and application of RNA-based immunotherapy to effectively utilize anti-cancer immune responses.
Furthermore, the growth of the market is attributed to the extensive research and development strategies carried out by biopharmaceutical companies for the production of novel therapeutic drugs. Leading market players are focusing on R&D and regional expansion strategies for better market penetration. For instance, in August 2022, Bluebird bio's BLUE.O gene therapy secured FDA approval for use in the treatment of subjects with a rare disorder requiring a regular blood transfusion process. The drug is priced at USD 2.8 million per unit.
The market players are extensively working towards collaborations, expansions, acquisitions, and huge capital investments to advance research in gene therapy to yield novel therapeutic drugs for the treatment of different types of cancers. For instance, in April 2022, GlaxoSmithKline plc declared the acquisition of Sierra Oncology to advance the therapeutic research on rare forms of cancer for USD55 per share featuring a total equity value of USD 1.9 billion.
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Regional Insights
North America accounted for the largest share of over 62.0% in 2022. This is attributed to the conducive environment facilitated by the government and the National Cancer Institute that supports research and development activities to enhance cancer therapeutics. Further, the presence of key market players in the region, their research efforts in devising gene therapy for cancer treatment, and collaborative efforts among market players to enhance research are boosting the market growth in the region. For instance, in August 2022, Merck & Co., Inc., collaborated with Orna Therapeutics Inc., for discovery, development, and commercialization of multiple programs, inclusive of utilization of mRNA for cancer gene therapy.
Europe is estimated to be the fastest-growing region over the forecast period due to increase in research funding for novel therapeutics by government bodies and increasing demand for novel therapeutics that could help combat the growing incidence of cancer cases across the region. Moreover, The European Union’s ‘Horizon Europe Mission on Cancer’ was launched in September 2021 so as to offer funds to a broad spectrum of activities that are intended to lower Europe’s cancer burden by accelerating research and innovation in cancer therapeutics. The mission is anticipated to help over 3 million cancer survivors by the year 2032.
Key Companies & Market Share Insights
Key players operating in the market are focusing on partnerships, strategic collaborations, new product launches, and geographical expansion in emerging and economically favorable regions. For instance, in January 2022, Ori Biotech Ltd. declared that it has achieved over USD 100 million funding in a Series B funding round. The funds will be used for expansion of key personnel to aid the launch of its innovative cell and gene therapy manufacturing platform. Some prominent players in the global cancer gene therapy market include:
Global Cancer Gene Therapy Market Segmentation
This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2018 to 2030. For the purpose of this study, Nova one advisor has segmented the global cancer gene therapy market report on the basis of therapy, end-use, and region:
Therapy Outlook
End-use Outlook
Table of Content
Chapter 1. Introduction
1.1. Research Objective
1.2. Scope of the Study
1.3. Definition
Chapter 2. Research Methodology
2.1. Research Approach
2.2. Data Sources
2.3. Assumptions & Limitations
Chapter 3. Executive Summary
3.1. Market Snapshot
Chapter 4. Market Variables and Scope
4.1. Introduction
4.2. Market Classification and Scope
4.3. Industry Value Chain Analysis
4.3.1. Raw Material Procurement Analysis
4.3.2. Sales and Distribution Channel Analysis
4.3.3. Downstream Buyer Analysis
Chapter 5. COVID 19 Impact on Cancer Gene Therapy Market
5.1. COVID-19 Landscape: Cancer Gene Therapy Industry Impact
5.2. COVID 19 - Impact Assessment for the Industry
5.3. COVID 19 Impact: Global Major Government Policy
5.4. Market Trends and Opportunities in the COVID-19 Landscape
Chapter 6. Market Dynamics Analysis and Trends
6.1. Market Dynamics
6.1.1. Market Drivers
6.1.2. Market Restraints
6.1.3. Market Opportunities
6.2. Porter’s Five Forces Analysis
6.2.1. Bargaining power of suppliers
6.2.2. Bargaining power of buyers
6.2.3. Threat of substitute
6.2.4. Threat of new entrants
6.2.5. Degree of competition
Chapter 7. Competitive Landscape
7.1.1. Company Market Share/Positioning Analysis
7.1.2. Key Strategies Adopted by Players
7.1.3. Vendor Landscape
7.1.3.1. List of Suppliers
7.1.3.2. List of Buyers
Chapter 8. Global Cancer Gene Therapy Market, By Therapy
8.1. Cancer Gene Therapy Market, by Therapy, 2023-2032
8.1.1. Oncolytic Virotherapy
8.1.1.1. Market Revenue and Forecast (2020-2032)
8.1.2. Gene-induced Immunotherapy
8.1.2.1. Market Revenue and Forecast (2020-2032)
8.1.3. Gene Transfer
8.1.3.1. Market Revenue and Forecast (2020-2032)
Chapter 9. Global Cancer Gene Therapy Market, By End-user
9.1. Cancer Gene Therapy Market, by End-user, 2023-2032
9.1.1. Research Institutes
9.1.1.1. Market Revenue and Forecast (2020-2032)
9.1.2. Biopharma Companies
9.1.2.1. Market Revenue and Forecast (2020-2032)
9.1.3. Diagnostic Centres
9.1.3.1. Market Revenue and Forecast (2020-2032)
9.1.4. Others
9.1.4.1. Market Revenue and Forecast (2020-2032)
Chapter 10. Global Cancer Gene Therapy Market, Regional Estimates and Trend Forecast
10.1. North America
10.1.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.1.2. Market Revenue and Forecast, by End-user (2020-2032)
10.1.3. U.S.
10.1.3.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.1.3.2. Market Revenue and Forecast, by End-user (2020-2032)
10.1.4. Rest of North America
10.1.4.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.1.4.2. Market Revenue and Forecast, by End-user (2020-2032)
10.2. Europe
10.2.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.2.2. Market Revenue and Forecast, by End-user (2020-2032)
10.2.3. UK
10.2.3.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.2.3.2. Market Revenue and Forecast, by End-user (2020-2032)
10.2.4. Germany
10.2.4.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.2.4.2. Market Revenue and Forecast, by End-user (2020-2032)
10.2.5. France
10.2.5.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.2.5.2. Market Revenue and Forecast, by End-user (2020-2032)
10.2.6. Rest of Europe
10.2.6.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.2.6.2. Market Revenue and Forecast, by End-user (2020-2032)
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10.3. APAC
10.3.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.3.2. Market Revenue and Forecast, by End-user (2020-2032)
10.3.3. India
10.3.3.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.3.3.2. Market Revenue and Forecast, by End-user (2020-2032)
10.3.4. China
10.3.4.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.3.4.2. Market Revenue and Forecast, by End-user (2020-2032)
10.3.5. Japan
10.3.5.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.3.5.2. Market Revenue and Forecast, by End-user (2020-2032)
10.3.6. Rest of APAC
10.3.6.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.3.6.2. Market Revenue and Forecast, by End-user (2020-2032)
10.4. MEA
10.4.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.4.2. Market Revenue and Forecast, by End-user (2020-2032)
10.4.3. GCC
10.4.3.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.4.3.2. Market Revenue and Forecast, by End-user (2020-2032)
10.4.4. North Africa
10.4.4.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.4.4.2. Market Revenue and Forecast, by End-user (2020-2032)
10.4.5. South Africa
10.4.5.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.4.5.2. Market Revenue and Forecast, by End-user (2020-2032)
10.4.6. Rest of MEA
10.4.6.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.4.6.2. Market Revenue and Forecast, by End-user (2020-2032)
10.5. Latin America
10.5.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.5.2. Market Revenue and Forecast, by End-user (2020-2032)
10.5.3. Brazil
10.5.3.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.5.3.2. Market Revenue and Forecast, by End-user (2020-2032)
10.5.4. Rest of LATAM
10.5.4.1. Market Revenue and Forecast, by Therapy (2020-2032)
10.5.4.2. Market Revenue and Forecast, by End-user (2020-2032)
Chapter 11. Company Profiles
11.1. Abeona Therapeutics
11.1.1. Company Overview
11.1.2. Product Offerings
11.1.3. Financial Performance
11.1.4. Recent Initiatives
11.2. Asklepios BioPharmaceutical
11.2.1. Company Overview
11.2.2. Product Offerings
11.2.3. Financial Performance
11.2.4. Recent Initiatives
11.3. Celgene
11.3.1. Company Overview
11.3.2. Product Offerings
11.3.3. Financial Performance
11.3.4. Recent Initiatives
11.4. Elevate Bio
11.4.1. Company Overview
11.4.2. Product Offerings
11.4.3. Financial Performance
11.4.4. LTE Scientific
11.5. GlaxoSmithKline
11.5.1. Company Overview
11.5.2. Product Offerings
11.5.3. Financial Performance
11.5.4. Recent Initiatives
11.6. Bluebird bio
11.6.1. Company Overview
11.6.2. Product Offerings
11.6.3. Financial Performance
11.6.4. Recent Initiatives
11.7. Genelux Corporation
11.7.1. Company Overview
11.7.2. Product Offerings
11.7.3. Financial Performance
11.7.4. Recent Initiatives
11.8. OncoGenex Pharmaceuticals
11.8.1. Company Overview
11.8.2. Product Offerings
11.8.3. Financial Performance
11.8.4. Recent Initiatives
11.9. Introgen Therapeutics
11.9.1. Company Overview
11.9.2. Product Offerings
11.9.3. Financial Performance
11.9.4. Recent Initiatives
11.10. Altor Bioscience
11.10.1. Company Overview
11.10.2. Product Offerings
11.10.3. Financial Performance
11.10.4. Recent Initiatives
Chapter 12. Research Methodology
12.1. Primary Research
12.2. Secondary Research
12.3. Assumptions
Chapter 13. Appendix
13.1. About Us
13.2. Glossary of Terms
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