San Diego Tech Startup, CureMatch, is Revolutionizing Precision Medicine in Oncology

Article for use by Clinical Research Currents.

For medical professionals, making course of treatment decisions for the 1.6 million new cancer diagnoses made each year in the US alone is an extremely difficult undertaking. This decision is further complicated by the heterogeneous nature of tumor make-up and behavior and the incredibly large number of combinations of drugs and treatments available.

CureMatch™, a San Diego-based startup selected by Xconomy as one of the 12 San Diego Tech Startups to watch in 2017, is revolutionizing decision-making support to medical professionals for oncology patients. It is a powerful, software-based solution that is positioning the company as a true leader in precision medicine for oncology.

Founded by Igor Tsigelny, PhD and Razelle Kurzrock, MD, CureMatch™ is taking on the challenges that face medical professionals in making treatment decisions by providing them with the highest level of personalized patient information to ensure the best possible care and quality of life for their patients. The company was founded when Tsigelny and Kurzrock identified the need for improved decision-support in their experience on the UCSD Tumor Board at the Moores Cancer Center at UCSD.

Dr. Kurzrock, a medical oncologist and a renowned expert in precision medicine, heads UCSD’s Center for Personalized Cancer Therapy at the Moores Cancer Center. Dr. Tsigelny is a Research Professor at the Department of Neurosciences, San Diego Supercomputer Center, and Moore’s Cancer Center (MCC), and a member of the MCC Molecular Tumor Board.

Through supercomputer processing of patient-specific profiles combined with oncology drug data, CureMatch provides decision-makers with personalized combination therapy options for individual patients. Any two cancer cases, even though they may be the same diagnosis, will manifest and respond to drug therapies vastly different depending on the person. And while there is an enormous quantity of cancer drugs on the market to address patient’s individual needs, this large quantity of options can be overwhelming, especially considering treatment plans often involve choosing a combination of three drugs.CureMatch is a powerful, software-based solution.

By processing the CLIA-validated genetic profile of a patient’s tumor in conjunction with data on the suitability of approved and investigational drugs, drug interactions, toxicity, and pharmacogenomics knowledge, CureMatch generates an optimized Combination Therapy Report with ranked options for courses of treatment that are best suited to the patient’s specific cancer profile.

CureMatch maintains all decision-making power in human hands while taking advantage of the incredible computational capabilities of their proprietary software to be the most informative support possible. Thus, it is no surprise that CureMatch is receiving a huge amount of attention in the life science industry. The company was selected for both the Five in 5 Competition in August and the 18th Annual SoCalBio Conference that took place last month, showcasing the company’s innovation in the presence of industry leaders and investors, and you can expect to see them excel in the new year.

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