Single Cell Insights | September 2024
Welcome to the third edition of "Single Cell Insights" - SEED Biosciences' single cell isolation newsletter! Today, we are focusing on high-precision isolation of single spheroids. Leave any of your thoughts and questions in the comments below!
New Application Note
High-precision isolation of single spheroids using Dispen3D
Spheroids are an emerging trend in cell culture science, as they demonstrate certain characteristics of other medically relevant cell aggregates, such as the formation of nutrient and oxygen gradients. These characteristics mean that they can be used to model complex tissues and tumor environments better than conventional monoclonal ‘2D’ cell cultures.
However, achieving consistent results from spheroid assays requires the capability to pre-select according to size and having the tools to isolate single spheroids in various plate formats. Until recently, this has been challenging, as traditional methods commonly used in industry for handling spheroids have relied on labor-intensive and error-prone manual techniques, such as pipetting by hand.
This application note demonstrates the use of the newest instrument on the market, Dispen3D, an affordable technology for spheroid handling that uses proven, impedance-based technology to gently and efficiently dispense single spheroids into individual wells.
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Events and Highlights
Attending the Bioprocessing Summit
Last month, the SEED Biosciences team attended the Bioprocessing Summit in Boston, MA. It was brilliant to connect with over 1,300 innovators in bioprocessing to explore cutting edge advancements in the field that are helping get treatments to patients faster and more efficiently.
The summit highlighted a clear need to create and isolate high efficiency single-cell clones that have significant therapeutic benefit. With the new DISPENCELL-S4, we are setting a new benchmark for cell line development processes. Our solution not only meets FDA requirements for monoclonality but also ensures GMP compliance with fully disposable kits, complete with BSE/TSE and sterility CoAs. This marks a significant advancement in our commitment to delivering reliable and high-quality solutions to the industry.
News for our US contacts
We are pleased to announce to our contacts in the United States that Thomas Haas (Tommy) has joined our team as a US colleague. We encourage you to reach out to him via email to arrange a meeting: thaas@seedbiosciences.com.
Find us at these upcoming events -
15-17 October | Festival of Biologics | Messe Basel, Basel | Booth #1136
17-19 November | International Scientific Conference on Cultured Meat (ISCCM) | Maastricht, The Netherlands