E-Merge Scientific Information Services

Toothpaste based on the mineral hydroxyapatite, popular across Asia and much of Europe today, is finding its first foothold in the U.S. But the idea behind this alternative to fluoride-based toothpaste was conceived here in a short-lived NASA field center more than 50 years ago. While working at NASA’s Electronics Research Center – active in Cambridge, Massachusetts, from 1964 to 1970 – Senior scientist Bernard Rubin discovered semiconductor crystals for electronics grew best in a silica gel..... https://lnkd.in/gGHNiKrY

🌟 Celebrating the Power of Women on International Women's Day 🌟 This International Women's Day, we pay tribute to the incredible strength, resilience, and achievements of women around the globe. 🌍✨ At E-Merge tech, we are privileged to work alongside some of the most inspiring women in our industry. They are leaders, innovators, and changemakers, driving progress and paving the way for future generations. Today, we celebrate their contributions and the immeasurable impact they have on our workplace and beyond. Let us continue to champion gender equality, support each other's journeys, and create a world where every woman can thrive professionally and personally. 🌺💼 To all the remarkable women at E-Merge tech and beyond: thank you for your dedication, passion, and unwavering commitment. Your stories inspire us, and your achievements empower us all. Here's to you—today and every day. 💪👩💼 #InternationalWomensDay #EmpowerHer #IWD2024 #inspireinclusion https://lnkd.in/dGX7T8X

Make no bones about it. Osteoporosis is a serious health issue. Osteoporosis affects an estimated 10 million Americans, according to the U.S. Department of Health and Human Services’ Office on Women’s Health. It is a disease that causes your bones to weaken. As your bones become more fragile, they become more susceptible to fractures – especially in the hip, spine, pelvis, shoulder and wrist. And that can have life-changing results, according to Christopher Shuhart, M.D., medical director of the Swedish Bone Health and Osteoporosis program. “When our bones break – particularly as we get older – we are likely to lose independence. At least half of people 75 or older who break their hip do not walk normally again. At least half of them have to go to a nursing home for some time for rehabilitation,” says Dr. Shuhart. “Our patients want to live their lives in the way they want to live them. And that’s what we want for them too. There’s nothing like a fracture to mess that up.” https://lnkd.in/gzfVXVCS

Humans grow and develop based on the instructions contained in our genetic material. A normal human cell should contain exactly 46 chromosomes. Chromosomes contain smaller units of genetic material called DNA inside the nucleus. DNA is a sequence of letters (A, T, C and G) that spell out the genetic code. The DNA is organised like words and sentences called genes. Humans have approximately 25,000 functional genes and each one influences a part of development and unique functions. These genes usually come in pairs. One copy is inherited from our mother and another from our father. A change in the spelling of a DNA sequence or the gene is called a mutation. Every person's DNA contains mutations which are usually harmless. However, some mutations are responsible for causing specific disease.....Read more https://lnkd.in/gqqajUAe

Identifying and accelerating drug development is big business. The costs in this industry are significant and finding pathways to optimize using AI methods is top of mind in this fast and evolving industry. Deloitte found that the average cost of developing a new drug among the top 20 global #biopharmas it studied rose 15% ($298 million) last year, to approximately $2.3 billion. That figure includes the average cost of developing a candidate from discovery through clinical trials to the market. Many #biopharmaceutical companies are using #AI to speed up drug development. For example, machine-learning models are trained using information about the protein or #amino-acid sequence or 3D structure of previous drug candidates, and about properties of interest. https://lnkd.in/g3xQ8gkv

Applying genetics to chemistry to find new small molecules For all the advances that have been made in it, drug discovery is still a hit or miss process, as much an art as a science. But new technologies are changing that, allowing companies to approach the process with a more precise eye. On today’s episode of the pharmaphorum podcast, Jason Park, CEO of Empress Therapeutics, discusses his company's novel approach to small molecule drug discovery. Empress Therapeutics applies AI algorithms to biosynthetic gene data sourced from the clinic to find new small molecule drug candidates. Park talks about why this approach hasn’t been widespread before and why Empress is betting big on it. https://lnkd.in/enr5UZCN

AI in Bioinformatics Market Soars from $2.8 Billion to $49.2 Billion by 2031. In the dynamic realm of bioinformatics, the global AI market hit a staggering $2,837.13 million in 2023, poised to skyrocket to an astounding $49,194.99 million by 2031. With a dazzling compound annual growth rate (CAGR) of approximately 42.85%, the journey ahead promises innovation, breakthroughs, and transformative advancements. The market’s pulse is quickened by groundbreaking developments. In June 2022, SOPHiA GENETICS obtained CE-IVD certification for its cloud-based SOPHiA DDMTM Platform, propelling global market expansion. Meanwhile, Google AI’s release of DeepVariant in January 2023 sets a new standard in variant calling, promising a paradigm shift in genomics accuracy... read more https://lnkd.in/dYHT_6z5

DNA sequencing is the process to determine the nucleotide order in a specific DNA molecule, which is useful when attempting to understand its function and consequent effects in the organism it resides in. DNA sequence assembly involves the alignment and merging of DNA fragments to reconstruct the DNA so that smaller sections of the genome can be analyzed. The analysis of DNA phase is the final step in genome analysis. It brings together the discoveries from the previous phases of https://lnkd.in/d9_ypVkG

Researchers at the University of Bristol have discovered that tiny external structures within the wax coating of blueberries are responsible for their blue color. This applies to lots of fruits that are the same color including damsons, sloes, and juniper berries. In the study, published today in Science Advances, researchers show why blueberries are blue despite the dark red color of the pigments in the fruit skin. Their blue color is instead provided by a layer of wax that surrounds the fruit which is made up of miniature structures that scatter blue and UV light. This gives blueberries their blue appearance to humans and blue-UV to birds. The chromatic blue-UV reflectance arises from the interaction of the randomly arranged crystal structures of the epicuticular wax with light. https://lnkd.in/djhNbVAD

RNA editing is gaining momentum. After decades of basic research into how to manipulate this complex molecule, at least three therapies based on RNA editing have either entered clinical trials or received approval to do so. They are the first to reach this milestone. Proponents of RNA editing have long argued that it could be a safer and more flexible...Read more https://lnkd.in/exWYqvvh