Main Change List:
Weapon Skill indicator has been moved down with the rest of the clusterfuck in the bottom left
Summoning and No Attacking icon are below the Weapon Skill indicator
Rune Counter has been moved to the top right
Save icon has been lowered a little to compensate
Width of the background for the Interact Prompt has been reduced by about a third
New Item pop up is now in the bottom right
Item log has been moved up to compensate and moved to the right a bit

Additional Versions

Minimal HUD:
Keeps things from Main changes unless specified
Summoning icon is next to the Rune Counter in the top left
No Attacking icon, Weapon slots and 3rd Spell/Item slots have been removed
Bottom left stuff is in the top left
Arrow/Bolt count is to the right of the slot like Bloodborne 
Buffs/Debuffs has been shifted to make room

No Interact Prompt Background:
The background for interact prompt is invisible

Side Status Effect Bars:
Moves the stats effect build up bars to the left above the Weapon Skill indicator
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Parameters I've edited in fe.gfx:
-Main:
Equips & Weapon Skill Indicator: sprites > DefineSprite (392: _01_000_FE_fla.Timeline_45) > frame 1
Summoning Icon: sprites > DefineSprite (475) > frame 1 > PlaceObject3 (200) Depth: 1
No Attacking Icon: sprites > DefineSprite (597) > frame 1 > PlaceObject3 (155) Depth: 1
Interact Prompt Background: sprites > DefineSprite (548/549) > PlaceObject2 (544) Depth: 1
Item Log: frames > frame 1 > PlaceObject2 (569): Depth: 497 (GetItemLog)
New Item Pop Up: frames > frame 1 > PlaceObject2 (596): Depth: 499 (GetItemList)

-Minimal:
Magic Specifics: sprites > DefineSprite (376) > frame 1
Item Specifics: sprites > DefineSprite (371) > frame 1
Arrow/Bolt Specifics: sprites > DefineSprite (380) > frame 1
Weapon Skill Indicator Name: sprites > DefineSprite (390) > frame 1 >PlaceObject2 (388) Depth: 3 (Text)
Item & Skill Name: sprites > DefineSprite (369) > frame 1 > PlaceObject3 (367) Depth: 1 (Name)
Buffs: sprites > DefineSprite (449) > frame 1 > PlaceObject2 (407) Depth: 1 (Equip)
Quick Menu: sprites > DefineSprite (467: _01_000_FE_fla.Timeline_44) > frame 1 > PlaceObject2 (402) Depth: 13 (ItemPanel2)

-Misc:
Status Effect Bars: frames > frame 1 > PlaceObject2 (507): Depth: 413 (ConditionGaugeList)

-No Longer Used:
Interact Prompt: frames > frame 1 > PlaceObject2 (551) Depth: 495 (ActionButton)
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I may listen to requests for versions with less changes, no guarantees though.

Incredible thanks to Dziggy and his Minimal HUD mod for the inspiration and making access to info and tools easy.

Installation:
Join the FromSoft modding server and download the beta UXM build from #tools-and-resources
Unpack and patch the game
Unzip the file in the games Game folder
Or
Download Mod Engine 2
Unzip the file in the mod folder

Of course be sure disable online and all that, I ain't posting a tutorial for that here though.