Hertie Institute for Clinical Brain Research

🎉 We are very proud of Matthias P. Baumann from Prof. Ziad Hafed's research group, the "Active #Perception Lab", on winning this year's #Attempto Prize from the Tübingen Attempto Foundation at the Eberhard Karls Universität Tübingen, a prize that recognizes outstanding achievements in #neuroscience research. 🧠 Matthias was awarded the prize for his paper "#Sensory tuning in #neuronal #movement commands", published in the journal PNAS, and his work on the role of the #superior colliculus #brain region in integrating #visual information into #motor signals to control #rapid #eye #movements. 👏 After winning the "HIH paper of the Year 2023 Award" this summer for it, this is now the second prize for him. Well done! 📜 Check out the paper: https://lnkd.in/eK9FBES3   👩🏼🎓 The second awardee was Roxana Zeraati from the Max Planck Institute for Biological Cybernetics for her publication on the processing of visual information in the brain on different time scales. 💰 The prize, worth 5,000 euros each, was presented at the Dies Universitatis ceremony at the University of Tübingen yesterday. Excellent work both of you! 📝 Read the full press release from the Tübingen University here (in German): https://lnkd.in/e5W2QVdH 🎙 If you want to hear more about their work: both awardees will give a talk in the Neurocolloquium on Thursday, October 31 at 4.15pm in the Lecture of the HNO in Tübingen plus in Zoom. Gemeinnützige Hertie-Stiftung #Gehirnerforschen #BrainResearch #Neuroscience

📅 Event tip: Wednesday, October 23, at 12:00-13:00 in the Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) in Tübingen. 🛗 The TNC Elevator #Pitches: #Neuroscientists from different Tübingen institutes and research areas are pitching their ideas for innovative projects, new research ideas, are looking for collaborations or are showcasing their work. 👏 Wonderful contribution from our own Dr. Michael Hahn, PostDoc in the "Human Intracranial #Cognitive #Neurophysiology" lab of Dr. Dr. Randolph Helfrich. Michael will talk about "Information coding in the hippocampal-neocortical #memory network during #sleep". Plus other great pitches by: 📌 Franziska Becker (Lab of Ellen Reisinger, Universitätsklinikum Tübingen) 📌 Janne Kristian Lappalainen (Lab of Jakob Macke at Eberhard Karls Universität Tübingen & International Max Planck Research School for Intelligent Systems (IMPRS-IS) 📌 Carolina Guidolin (Lab of Manuel Spitschan PhD, Max Planck Institute for Biological Cybernetics) & 📌 Pablo R. Grassi (Lab of Andreas Bartels, Werner Reichardt Centre for Integrative Neuroscience) 🎉 Everyone is cordially invited.

🎉 Congratulations to Ladina Müller and Malin Schulze on receiving the "Johannes Dichgans Doctoral Scholarship" from the HIH. 🧠 In her doctoral thesis, Ladina Müller will research "#Cilia in Models of Autosomal-Dominant #Parkinson's Disease" and will be supervised by Prof. Philipp Kahle, head of the research group "#Funtional #Neurogenetics" at the HIH and by Dr. Nisha Mohd Rafiq from the Interfaculty Institute of Biochemistry (IFIB) at the Eberhard Karls Universität Tübingen. 🧬 Malin Schulze will focus on the topic of "Digital motor endpoints of hereditary #spastic #spinal #paralysis and spastic #ataxia: Identification of more sensitive study endpoints for #degenerative diseases of the pyramidal tract" and will be supported by Prof. Matthis Synofzik, senior physician and head of the Section for "Translational #Genomics of #Neurodegenerative Diseases" at the HIH and Dr. Dr. Andreas Traschütz, specialist and clinician scientist at the Hertie Center for Neurology. Both were able to convince the reviewers and will now receive the Johannes Dichgans doctoral scholarship from the Hertie Institute for one year. We wish both all the best for their future endeavors 🙌 Gemeinnützige Hertie-Stiftung #Gehirnerforschen #BrainResearch #Neuroscience

📢 If you're at the #SfN2024 in Chicago 🇺🇸, go have a look at Booth #1765 and say Hi 👋 - the HIH is also part of "#Neuroscience in Germany" 🧠

Join the 🖥 🧠 Hertie Institute for AI in Brain Health 🧠 🖥 as an early career group leader (f/d/m)! If you just finished your PhD and you have exciting ideas how to improve #brainhealth with #machinelearning or #artificialintelligence, this could be for you! Join us Eberhard Karls Universität Tübingen in a great environment including Tübingen AI Center, Cyber Valley, Hertie Institute for Clinical Brain Research, Universitätsklinikum Tübingen and others. Submit your application at https://lnkd.in/eyBDZgVW

🧠 Tomorrow, on September 21, 2024, is World Alzheimer's Day. #Alzheimer's - a dementia disease that affects around 55 million people worldwide, and around 1.8 million in Germany. This number will continue to rise. By 2050, around 2.7 million people in Germany will be affected. Prof. Mathias Jucker, head of the Department of "#Cellular #Neurology", just published a new paper in Science Magazine with Co-Author Larry C. Walker from the Department of Neurology & the Emory National Primate Research Center, at the Emory University, Atlanta, Georgia: “The #prion principle and #Alzheimer’s disease”. They show that similarities to #molecular mechanisms underlying prion diseases may help to refine Alzheimer’s disease #therapies. 📝 Check out the Science paper here: https://lnkd.in/eVxQ6sye In addition, he speaks in an interview with the Gemeinnützige Hertie-Stiftung about the EU decision against #Lecanemab, its impact on Alzheimer's research and alternative therapeutic approaches. 🎙️ Read the interview in German here: https://lnkd.in/eg6J_BnT #Weltalzheimertag #WorldAlzheimersDays24 #Gehirnerforschen #BrainResearch #Neuroscience

***ESMO Annual Meeting 2024 in Barcelona*** Back from a great annual meeting of ESMO - European Society for Medical Oncology, inspired by great talks, discussions and networking with fantastic colleagues and friends. Our abstract was selected for an oral presentation during the “Proferred paper session on CNS Tumors”. We presented first results from the Dose Escalation Phase of the First-in man phase 1 clinical trial investigating mRNA vaccine candidate CVGBM from CureVac in newly diagnosed MGMT-unmethylated glioblastoma (NCT05938387).  Key messages: -       The overall safety profile of CVGBM was acceptable up to the highest dose level of 100 µg, and the DSMB recommended 100 µg for the expansion phase.  -       Preliminary immunogenicity results demonstrate the induction of tumour-associated antigen-specific T cell responses in 77% of evaluable patients. The majority of immune responses (84%) were primed and activated de novo by CVGBM. The expansion phase has recently continued enrollment. We feel encouraged by these results, and I am grateful for this endeavor in a synergistic and interdisciplinary team including the CureVac team Ulrike Gnad-Vogt, Dr. Myriam Mendila, Sven Koch, Martin Falk, Peter Kelemen (and many more!), outstanding colleagues from clinical sites, and of course a great team in my Department Mirjam Renovanz, Ute Walter, David Rieger, Lucia Grosse, Marion Jeric, Sigrid Baltes (and many more!). Together, we look forward to continuing our journey and to contributing to the development of new therapeutic strategies for our patients. The satellite symposium “Precision Medicine: From Early Detection to Improved Outcomes in Patients with IDH Mutations” from Servier was another inspiring team event. Together with Teresa Macarulla, Silvia Stacchiotti, John Bridgewater, we discussed the role and impact of IDH mutations as disease-defining markers and as a therapeutic target in different tumor entities and  exchanged our clinical experiences and perspectives. Many thanks to Mirella Fares, MBA, MPH, PharmD, Hakam G., Lene Bering and many more behind the scenes for initiating this symposium at the annual ESMO meeting! Save the date: ESMO annual meeting 2025 in Berlin, Germany, 17-21 October 2025 Eberhard Karls Universität Tübingen Hertie Institute for Clinical Brain ResearchGemeinnützige Hertie-Stiftung Universitätsklinikum Tübingen #ESMO #neurooncology #CNS #teamwork #future

🙏 We are very proud that our very own Prof. Ghazaleh Tabatabai, head of the Department of “#Neurology and Interdisciplinary Neuro-#Oncology”, is part of the brand new 🎙 #Podcast of the Excellence Strategy of the Eberhard Karls Universität Tübingen "Key to my Research". 🧠 In the episode "How Smart are #Tumors?“, Ghazaleh Tabatabai shares her groundbreaking research and insights into improving #therapeutic strategies for these formidable diseases, how tumor #cells evade therapy, and how she and her team are identifying windows of opportunity where tumor cells are vulnerable. 👏  A big thank you to the host Jennifer Raffler and the production team Chris Veit & Joti Fotiadis from changing time! Great job! ➡ Listen to the full episode on Spotify by following the link: https://lnkd.in/emZYPTyH #Neuroscience #Neurooncology #BrainResearch #SciencePodcast #KeytomyResearch #GehirnErforschen Gemeinnützige Hertie-Stiftung

🧠Wie unser Schlaf das Gehirn schützt und stärkt Schlaf ist weit mehr als nur Erholung – er ist entscheidend für unsere Hirngesundheit. Dr. Dr. Randolph Helfrich vom Hertie Institute for Clinical Brain Research erforscht, wie der Schlaf unsere Gedächtnisleistung, Stimmung und sogar neurologische Erkrankungen wie Epilepsie beeinflusst. 🌙In unserem neuesten Interview berichtet er über den REM-Schlaf und seine Bedeutung für die Regulation der Hirnaktivität. Diese Forschung hat weitreichende Implikationen – von der Prävention bis zur Behandlung neurologischer Erkrankungen. 🌐Im vollständigen Interview auf unserer Website erfahren Sie mehr über die Zusammenhänge von Schlaf und Gehirn: https://lnkd.in/e3uj5v5c #Neurowissenschaften #Schlafforschung #REMschlaf #HertieStiftung #Gesundheit #GehirnErforschen #Hirnforschung

🎉 It's been a wonderful Neuroscience Campus Get Together last week, jointly organized by the HIH, the Werner Reichardt Centre for Integrative Neuroscience (CIN), the Tübingen location of the Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the Neurological University Clinic. Plus, the newly founded Hertie Institute for AI in Brain Health as the "new kid on the block".   🍾Special congratulations go to Matthias P. Baumann from the research group of Prof. Ziad Hafed for winning the "HIH Paper of the Year Award" for his publication "Sensory tuning in neuronal movement commands“, published in PNAS. 👉 Link to the paper: https://lnkd.in/eGjUKN-v 🙏Thanks to everyone for coming and celebrating with us. Enjoy the summer holidays ☀️ Gemeinnützige Hertie-Stiftung #GehirnErforschen #Neuroscience