Leibniz-Institut für Virologie (LIV) hat dies direkt geteilt
A new study led by Prof. Sabine Windhorst’s group, in collaboration with Dr. Roland Thuenauer and Dr. Rudolph Reimer from the Leibniz-Institut für Virologie (LIV) Hamburg - home to the Nikon Centre of Excellence #NCofE - sheds new light on cancer cell communication. This research in the Journal of Extracellular Vesicles has uncovered a novel pathway for the oncogene CEP55 to enter cancer cell exosomes. Leveraging Nikon’s state-of-the-art imaging technology, the team used: 🔬 Ti2 microscope with CSU-W1 SoRa for high-resolution live-cell imaging 🔬 AX/AX R with Nikon Spatial Array Confocal (NSPARC) for detailed cellular visualisation 🔬 A1+ microscope for correlative light and electron microscopy (CLEM) Their findings reveal that CEP55 follows a non-canonical trafficking route, rather than the traditional early-to-late endosome pathway. This discovery enhances our understanding of cellular communication in cancer and could help pave the way for new therapeutic strategies. Congratulations to all the authors on this important achievement! 👏 Read the full article: https://lnkd.in/ezJYhVxT Dahlstroem, C. et al. (2025) ‘Mechanism of centrosomal protein 55 (CEP55) loading into exosomes’, J. Extracell. Vesicles, 14(2). doi:10.1002/jev2.70046. #NikonScienceSpotlight #NikonMicroscopy #CancerResearch #Exosomes #CellBiology