Dianox

Spinogenix is starting human trials for SPG302, a once-a-day pill designed to regenerate lost nerve cell connections as a treatment for schizophrenia. This new approach aims to address synapse loss and improve treatment outcomes for patients resistant to existing therapies. The Phase 2 clinical trial is actively enrolling participants to evaluate the pill's safety and effectiveness. Read more: https://lnkd.in/dSsXhKFH #medical #research #schizophrenia #science #treatment

Discovery of new type of cell with potential to boost tissue repair. Researchers have discovered a new type of bipotent progenitor cell called 'EndoMac,' which matures into both endothelial cells and macrophages, significantly enhancing wound healing. These cells, found in the outer layer of the aorta in adult mice, help grow blood vessels during the healing process. In experiments with diabetic mouse models, transplanting these progenitor cells led to dramatic improvements in wound healing within days. The study aims to identify a human equivalent and explore the cells' potential for healing skin and muscle, marking a significant advancement in blood vessel regeneration and chronic wound treatment. Read more: https://lnkd.in/dspxgmKg #medical #research #woundhealing #chronicwound #medtech

A recent study led by Oregon Health and Science University found that placing defibrillator pads in an anterior-posterior (AP) configuration—one on the chest and one on the back—can increase survival rates after an out-of-hospital cardiac arrest (OHCA) by 264%. Traditionally, pads are placed in an anterior-lateral (AL) position, which has been linked to lower survival rates. Analyzing data from 255 patients with shockable heart rhythms, the researchers discovered that those with the AP placement had significantly higher rates of return of spontaneous circulation (ROSC). This new positioning may allow for a more effective delivery of electrical current to the heart, although practical challenges exist in emergency situations. The findings could spur further research into improving resuscitation methods. Read more: https://lnkd.in/duT_kd6a #medical #research #hearthealth #cardiacarrest #medtech

Giving T cells extra batteries supercharges them against cancer. Scientists have developed a novel method to supercharge T cells, our immune system's primary cancer fighters, by giving them "extra batteries" in the form of mitochondria, the cell's energy producers. Cancer often exhausts T cells by draining their energy, but researchers at Brigham and Women's Hospital found that donating mitochondria from bone marrow stromal cells to T cells significantly enhanced their ability to attack tumors. In mouse studies, these "Mito+" T cells shrank tumors and dramatically improved survival rates. This breakthrough could pave the way for more effective immunotherapies using organelle transplants. Read more: https://lnkd.in/dhgjfqnk #medical #research #cancer #oncology #tcell

Scientists at Aston University have developed a promising new treatment for osteosarcoma, the most common form of bone cancer, using bioactive glass laced with gallium, a toxic metal. In lab tests, the glass killed 99% of cancer cells within 10 days while sparing healthy bone cells. The gallium targets cancer cells through specific receptors, allowing it to attack the tumor without harming healthy tissue. The bioactive glass also shows potential for promoting bone regeneration, though higher gallium concentrations currently inhibit this. Further research aims to refine the treatment and test its safety and effectiveness in animal models. Read more: https://lnkd.in/eXFFUSu8 #medical #research #cancer #oncology #bonecancer

Researchers from Queens University Belfast, Edith Cowan University, and Monash University have found that consuming flavonoid-rich foods and drinks, such as red wine, berries, dark chocolate, and tea, can significantly reduce the risk of developing dementia. Adding six servings of these antioxidant-rich items daily was associated with a 28% lower risk of dementia among individuals aged 40 to 70, particularly those with high genetic risk or depression symptoms. These findings emphasize the potential of a flavonoid-enhanced diet in preventing age-related cognitive decline and maintaining brain health. Read more: https://lnkd.in/euUFGwPz #medical #research #brainhealth #university #dementia

World-first ADHD headband treats symptoms in 20 minutes per day. Neurode, an Australian startup, has developed a non-invasive headband that treats ADHD by delivering light electrical stimulation to the prefrontal cortex for 20 minutes daily, improving focus and impulse control without the side effects of traditional medication. Linked to a smartphone app for real-time brain activity tracking, the device offers an accessible, drug-free alternative for managing ADHD symptoms. Co-founded by neuroscientist Nathalie Gouailhardou, the headband is currently being tested, and future plans are to expand to cognitive decline and depression treatments. Read more: https://lnkd.in/dqdk5Auv #medical #research #technology #wearables #adhd

Octopus-inspired medical patch offers irritation-free skin adhesion. Researchers at King Abdullah University of Science and Technology (KAUST) have developed an octopus-inspired medical patch called the AMOS patch, which provides irritation-free adhesion to the skin. The patch uses tiny suction cups made from biocompatible polydimethylsiloxane (PDMS) to securely attach to the skin without causing irritation. Tested on a cyclist over a 30-day journey, the patch remained effective, even on wet or hairy skin, making it a promising tool for wearable health monitoring. Read more: https://lnkd.in/dwKSNB3c #medical #research #science #wearables #medtech

Immune cell injection significantly boosts healing of bone, muscle & skin. Researchers have discovered that injecting regulatory T cells (Tregs) directly into injured bone, muscle, and skin significantly accelerates healing. Tregs, which manage immune responses, were administered via a fibrin hydrogel to mice with acute injuries. The study found enhanced tissue regeneration in bone, muscle growth, and faster skin wound closure compared to mice without Treg treatment. The Tregs switched immune cells to an anti-inflammatory state, key for healing, and their effectiveness was tied to the secretion of interleukin-10 (IL-10). This opens potential for Tregs in regenerative medicine therapies. Read more: https://lnkd.in/d6bkMBwU #medical #research #injury #woundhealing #hydrogel

Researchers at Italy's Sant'Anna School of Advanced Studies have developed a prosthetic hand that is controlled by tiny magnets implanted in muscles, offering a simpler and more effective alternative to traditional thought-controlled prosthetics. In a successful trial, a test subject named Daniel, who lost his hand in an accident, had six small magnets implanted in key muscles in his arm. These magnets, detected by sensors in a carbon fiber cuff, enabled precise control of the prosthetic hand's movements. Daniel was able to perform tasks such as opening jars, using tools, and modulating his grip on fragile items. This innovation could significantly improve prosthetics for a wider range of amputees. Read more: https://lnkd.in/drhPvNU2 #medical #technology #prosthetic #sensors #research