We are happy to share an in-depth review article, authored by Gubra scientists and available now at #DrugDiscoveryToday, on the possibilities offered by 3D light sheet fluorescence microscopy in preclinical and clinical drug discovery process. Read and download the full paper here: https://lnkd.in/dGzCDTzN #LSFM #PreclinicalImaging #DrugDiscovery
Om os
Founded in 2008, we are a biotech company with two primary areas of business: Preclinical contract research organization (CRO) services and proprietary early target and drug discovery programs. Our focus is the metabolic space (e.g. obesity, diabetes, NASH and gastrointestinal diseases), where we specialize in peptide chemistry, in vivo pharmacology, ex vivo assays, molecular pharmacology, histology, imaging, stereology, NGS (next generation sequencing) and bioinformatics. Gubra is an abbreviation for GUt and BRAin, the original key focus areas of our research and expertise. We work with some of the most interesting and loyal partners and customers from across the world in the pharmaceutical and biotech industry as well as academia. Through a constant focus on high quality, scientific excellence, speed and solid teamwork, we have established ourselves as a highly professional and competent partner in the market.
- Websted
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http://www.gubra.dk
Eksternt link til Gubra
- Branche
- Forskning inden for bioteknologi
- Virksomhedsstørrelse
- 201-500 medarbejdere
- Hovedkvarter
- Hoersholm
- Type
- Aktieselskab
- Grundlagt
- 2008
- Specialer
- in vivo pharmacology, histology, stereology, diabetes, obesity, NASH, Gastrointestinal diseases, peptide chemistry, molecular pharmacology, next generation sequencing, bioinformatics, ex vivo assays og Imaging
Beliggenheder
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Primær
Hørsholm Kongevej 11b
Hoersholm, 2970, DK
Medarbejdere hos Gubra
Opdateringer
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Probably the most comprehensive phenotyping and pharmacological validation study conducted in the bleomycin-induced #IPF mouse model to date. In the paper just published in Physiological Reports, we in-depth characterized the model for utility in preclinical drug development. Read the recent Gubra paper here: https://lnkd.in/dByZQcBd
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Reflecting on an impactful week at #SFN2024 in Chicago! We had a great time connecting with familiar and new faces while showcasing our latest light sheet imaging pipeline. Throughout the event, we presented five posters, held an oral presentation and were selected for a press conference to introduce how light sheet 3D imaging can longitudinally track pathological alpha-synuclein spreading in the intact mouse brain. We are leaving the conference thrilled by the positive reactions, c-Fos studies demand and new insights! Missed the event? Not to worry - you can explore all our posters and get in touch with us here: https://lnkd.in/e6JwGyj2 Jacob Hecksher-Sørensen, Henrik Björk Hansen, Allison Butt, PhD, Frederikke Lynge Sørensen, Lea Lydolph, Yasir Gallero-Salas, Stanislav Nagy, Barbora Krajníková
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Hvis du er motiveret, åben for at lære og trives med praktisk arbejde i et effektivt og systematisk laboratoriemiljø, kan du blive en del af vores dynamiske team, da vi netop nu søger en laborantelev til vores team. Gubra er et biotekselskab der, udover egne forskningsprojekter og partnerskaber, også laver kontraktforskning. En af Gubra’s kerneværdier er, at vi arbejder sammen som et team på tværs af hele organisationen og altid hjælper hvor der er behov. Den ideelle kandidat er derfor både en teamplayer, der kan fungere godt med kolleger på tværs af Gubra, og samtidigt klar til at lære en masse.
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Are you experienced with in vitro cell based assays? Are you eager to use your experimental skills and expertise in drug discovery research? If so, we have an exciting opportunity for you at Gubra. Gubra is looking for a Laboratory Technician (laborant) to join our Molecular Pharmacology department to support our internal and partnered drug discovery activities.
Laboratory Technician (Laborant) for Molecular Pharmacology
career.gubra.dk
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This month, you'll have the chance to talk to us in person at three major conferences. Will we see you at any? Society for Neuroscience - Stop by our booth #1632 to talk with Jacob Hecksher-Sørensen and other Gubra scientists and see our posters here: https://lnkd.in/e6JwGyj2 ICLAF - Reach out to Michael Feigh and don't miss out on the below poster presentations: 1. Reproducible lung protective effects of a tgfßr1/alk5 inhibitor in a bleomycin-induced and spirometry-confirmed mouse model of IPF - Download here: https://lnkd.in/dyGGsxyZ 2. Repetitive installations of bleomycin induce persistent progressive lung fibrosis in a mouse model of IPF - Download here: https://lnkd.in/dnXptWJK American Society of Nephrology Kidney Week - Our team in San Diego will also be excited to see you at the booth #2233. Book a meeting with Michael Christensen here: https://lnkd.in/e8uV4Q4N
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Exciting news! You can now order a c-Fos study in no time through our newly launched online shop: www.gubra.dk/shop. Are you attending #SFN this week? Come by our booth #1632 to discuss how this can streamline your work. See you in Chicago. #NeuralImiging #CNS #Neuroscience #cFos #Neurology
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Are you ready to discuss the latest advances and applications in preclinical CNS research with us in person? Then join our delegation at the Society for Neuroscience conference in Chicago on the 5-9th of October, at booth #1632. Our schedules will be busy, so feel free to drop us a message and schedule a meeting. Here's a sneak peek of the talks and posters we'll be presenting: Sunday, October 6, 2024: - 10:00-11:00 (Press Conference): Whole-brain 3D quantification of alpha-synuclein spreading in a mouse model of Parkinson’s disease - 14:00-14:15 (Oral Presentation NANO17.05): Whole-brain mRNA imaging unveils the dynamics of neuroinflammation after stroke Monday, October 7, 2024: - 13:00-17:00 (Poster C21): Whole-brain 3D quantification of alpha-synuclein spreading in a mouse model of Parkinson’s disease - Download: https://lnkd.in/dMj5xREC Tuesday, October 8, 2024: - 09:00-10:00 (Poster Z38): Multimodal stereotaxic rat brain atlas for automated image analysis and data integration in 3D - Download: https://lnkd.in/dr_-HFUZ Wednesday, October 9, 2024: - 08:00-09:00 (Poster B132): Brain delivery and efficacy of a BBB shuttle-enhanced aducanumab biosimilar in a mouse model of Alzheimer’s disease - Download: https://lnkd.in/dPMDpmgQ - 09:00-10:00 (Poster B24): Quantitative 3D imaging of orexin and orexin receptor distribution in the intact mouse brain - Download: https://lnkd.in/dr5AxEb4 - 16:00-17:00 (Poster Y23): Jumping dimensions: Integration of multimodal imaging into a unified brain atlas space Download: https://lnkd.in/dFdcnGeu Looking forward to connecting at #SFN2024! #SFN #Neuroscience #NeuralImaging #BrainResearch #NeurodegenerativeDiseases
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Interested in learning how whole-brain imaging can be used to measure neural activity in response to #obesity therapies? Gubra is leading in 3D whole-brain quantification of c-Fos expression (proxy for neuronal activation) and mapping brain activation patterns at single-cell resolution following anti-obesity drug treatment. Check out our latest blog post for insights: https://lnkd.in/dN9hHAtt #TheGubraBlog #NeuralImaging #AntiObesityResearch
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Do you want to deliver analytical work while being hands on in a collaborative work environment? Do you excel at turning data into actionable insights that drive business growth and you like working with cross-disciplinary collaborating teams, with an entrepreneurial setup, then this role could be an excellent fit for you. And you will do so in a fantastic environment where everyone wants to help and drive things forward.
Gubra is looking for a Financial Business Analyst – to join our Finance department
career.gubra.dk