We are proud to share the findings from the multicenter study on high-resolution HLA genotyping using third-generation sequencing technology conducted by Stéphane Buhler, Maja Nørgaard, Rudi Steffensen, Kirstine Kløve-Mogensen, Bjarne Møller, Rebecca Grossmann, Sylvie Ferrari-Lacraz, and Claudia Lehmann. The study explored the efficacy of nanopore sequencing for HLA typing and used the NanoTYPE™ kit and NanoTYPER™ software to compare the results with next-generation sequencing (NGS) across 381 samples. The findings were impressive, with a 99.58% concordance for 11 HLA loci (HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, -DQA1, -DQB1, -DPA1, and -DPB1). This high level of accuracy underscores the potential of nanopore sequencing in diagnostic laboratories, particularly for stem cell transplantation and investigating various disease associations. https://lnkd.in/gENm_5Ec #Genomics #HLAtyping #NanoTYPE #NanoTYPER #ThirdGenerationSequencing #HealthcareInnovation #StemCellResearch #ClinicalResearch #NanoporeSequencing
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