Metabolon, Inc. reposted this
Metabolon, Inc. and the Scottish Early Rheumatoid Arthritis (SERA) Study announce partnership to better understand the molecular mechanisms of rheumatoid arthritis. #microbiota | #health | #digitalhealth | #medicine
Almost every factor that affects health – from genetics and the microbiome to disease and lifestyle – exerts its influence by altering metabolite levels in the body or other biological system. By producing the most accurate and comprehensive picture of the collection of metabolites, known as the metabolome, from a single biological sample, Metabolon can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of disease, medical intervention, diet or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers some of biology’s most difficult questions. Metabolon's unrivaled capability to look deep into the metabolome has enabled us to build the world’s largest library of compounds that currently includes 5,200+ total known molecules. Our proprietary Precision Metabolomics™ platform, combined with the world's most experienced metabolomics scientists, delivers biologic insights and identification of novel commercial opportunities for drug discovery and development, through clinical trials and life cycle management. Metabolon’s expertise is also accelerating research and product development for clients in academia, population health, consumer products, and nutrition industries. Founded in 2000 and based in Research Triangle Park, North Carolina, Metabolon has conducted more than 10,000 independent and collaborative studies, resulting in 2,000+ publications in leading peer-reviewed journals. For more information about our technology, products and services, please visit www.metabolon.com.
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Metabolon, Inc. reposted this
Metabolon, Inc. and the Scottish Early Rheumatoid Arthritis (SERA) Study announce partnership to better understand the molecular mechanisms of rheumatoid arthritis. #microbiota | #health | #digitalhealth | #medicine
🚀 Featured Publication - "A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes" 👩🔬 First Author: Anna Halama, 👨🔬 Last Author: Karsten Suhre 🗞 Full Publication: https://lnkd.in/ere-egfe We get to support all kinds of interesting research from around the world and there is always a buzz internally when our clients publish new outcomes with metabolomics data. The concept of the molecular human, championed by Dr. Anna (Ania) Halama and Dr. Karsten Suhre, is an ambitious and achievable vision for fully integrated and collaborative multiomics data and hypotheses generation. The goal - demonstrated in this study is to accelerate our understanding of the relationship between genetics, biology, environments, and lifestyles and how different combinations of biological markers can predict disease onset and severity or inform research disease prevention and new drug development. If you want to learn more about this work, we have an on-demand webinar, presented by Dr. Halama, for you to access below: ▶ Watch on demand: https://lnkd.in/e_YivzfT 🗞 **Abstract:** In-depth multiomic phenotyping provides molecular insights into complex physiological processes and their pathologies. Here, we report on integrating 18 diverse deep molecular phenotyping (omics-) technologies applied to urine, blood, and saliva samples from 391 participants of the multiethnic diabetes Qatar Metabolomics Study of Diabetes (QMDiab). Using 6,304 quantitative molecular traits with 1,221,345 genetic variants, methylation at 470,837 DNA CpG sites, and gene expression of 57,000 transcripts, we determine (1) within-platform partial correlations, (2) between-platform mutual best correlations, and (3) genome-, epigenome-, transcriptome-, and phenome-wide associations. Combined into a molecular network of > 34,000 statistically significant trait-trait links in biofluids, our study portrays “The Molecular Human”. We describe the variances explained by each omics in the phenotypes (age, sex, BMI, and diabetes state), platform complementarity, and the inherent correlation structures of multiomics data. Further, we construct multi-molecular network of diabetes subtypes. Finally, we generated an open-access web interface to “The Molecular Human” (https://lnkd.in/eM9fdp9j), providing interactive data exploration and hypotheses generation possibilities. #Multiomics #PrecisionMedicine #DiabetesResearch #Genomics #Proteomics #Metabolomics #Transcriptomics #metatranscriptomics #lipidomics #molecularhuman #phenotype #epigenome #transcriptome #genome #phenome #mwas #gwas #pwas
Metabolon and the Scottish Early Rheumatoid Arthritis (SERA) Study Announce Partnership to Better Understand the Molecular Mechanisms of Rheumatoid Arthritis. Learn more here: https://mtbln.co/bdrwj9
📰 Metabolomics in the news - It is exciting to watch the growing popularity of metabolomics in routine, clinical, and commercial research. This news story shows how metabolomics is increasingly becoming a consumer-interest topic with wide-reaching benefits from sports science to disease research and drug development. 🎤 Interview: Travis Nemkov 📽 https://lnkd.in/eySzUzMG
Metabolon is excited to be exhibiting at the Nordic Metabolomics Conference in Finland this week. Stop by our table to speak to our experts about how metabolomics can advance your research. #nmetc2024 #getinspiredbyscience
Turku, Finland, thank you for the warm (66.2 degrees) welcome for our visit to this year's Nordics Metabolomics Conference! #NMetC2024 This year we are a gold sponsor! Yesterday Natasa Giallourou shared the recent successes of our clients across large cohort population health studies, integrated multiomics studies, MASLD, microbiome research, and the overarching benefits of our bioinformatics platform. If you haven't yet stopped by, please visit Booth 10 and say hello to the team - Natasa Giallourou, Simon Stritt, and Simone de Faria Maraschin, PhD who will be happy to answer your questions! #metabolomics #microbiome #multiomics #lipidomics #masld #populationhealth #bioinformatics #nmetc2024 #nordicsmetabolomics #biomarkers #biomarkerdiscovery #gwas #mgwas #metabolome #phenotype @
Join us for our webinar on August 28th highlighting the utility of metabolomics in multiomic studies. Our Director of Discovery and Translational Sciences will discuss 5 key publications that demonstrate the value of metabolomics. https://mtbln.co/sudml9
Dive into our new blog providing an extensive look into the biochemical virtuosity of prokaryotes underlying the concept of meta-organism and learn how Metabolomics is an invaluable research tool to enhance multiomic microbiome-related research workflows. https://mtbln.co/69ysx8
Discover how metabolomics data provides valuable insights into metabolism’s dynamic and multifaceted nature, offering researchers a powerful tool to unravel biological complexity in our application book. https://mtbln.co/tbdosf
At Metabolon, we use metabolomics to elucidate the physiological changes that everyday life brings. Our industry-leading expertise was essential to generating the data used by the HuMet Repository. https://mtbln.co/60fhys