HRB Clinical Research Facility - University College Cork

Are you involved in the design of clinical trials? Our own Dr. Frances Shiely has a guide to help you randomise your trial and avoid pitfalls: Summary: - Understanding is not really the issue, acceptability is. - Lowest acceptability associated with a ‘loss of control’, e.g., the computer will determine which treatment, you will give you your right, lottery, roll of dice. - Analogies to gambling or luck are strongly disliked. - ‘Why randomisation is required’ and ‘phrases elaborating on randomisation’ had the highest levels of acceptability and understanding. - Simple language.   What to do in practice: - Exclude any references to gambling. - Remove phrases that mention computers or automation conducting randomisation. - Avoid comparative phrases (toss of a coin, roll of a die, like a lottery). - Consider the diversity of society and use phrases acceptable to everyone. - CTUs/CRFs tend to use the same templates. Modify them to suit the population, intervention and the intended target group. Download the full paper: https://lnkd.in/e6kRGJKD #clinicaltrials #research #trialdesign Dr Sandra Galvin, Health Research Board (HRB), HSE Research and Development, HRB National Clinical Trials Office (NCTO), Trials Methodology Research Partnership (TMRP), HRB- Trials Methodology Research Network Ireland, The School of Public Health UCC, UCC Medicine and Health, Fai Ng, Darren Dahly PhD

To support the implementation of inclusive clinical trials on a larger scale we are developing materials to support you in conducting workshops and promoting this idea across the clinical research community. https://lnkd.in/erh-YQfm HRB Clinical Research Facility - University College Cork, HRB National Clinical Trials Office (NCTO), The School of Public Health UCC,UCC Medicine and Health, Trial Forge, ECRIN (European Clinical Research Infrastructure Network), Faculty of Medicine, Masaryk University, CZECRIN #inclusiveclinicaltrial, #DEI, #training, #trialdesign

👏 Congratulations to the OPTIMATE Team on completing their recruitment phase with a whopping 642 patients across 3 sites! 👏   OPTIMATE is a groundbreaking trial that tackles medication risks for the over 70s. With 3 sites (Ghent University, Cork University Hospitals Group & University Hospital Waterford) testing new ways to reduce unnecessary hospital visits and improve drug safety for older patients with multiple health conditions and help with their medication management. The goal is to save lives and healthcare costs!   #research #clinicaltrials #polypharmacy   John Cooke, Mirko Petrovic, Annemie Somers, Emma Wallace, Health Research Board (HRB), HSE Research and Development, Brendan Palmer, Darren Dahly PhD, Frank Moriarty, DENIS O'MAHONY, Kieran Dalton,Perrine Evrard, Bronagh Bolger, Ine Simal, Aoibheann Kavanagh, Emma Cobbe, June Considine

We generate lots of clinical research-waste due to poor study designs, mismanaged data, and flawed analyses. This harms patients. Awareness of this is increasing & leading to increased external scrutiny of research practices. So get your house in order or risk reputational damage. Hear more about this with the link below: https://lnkd.in/eQMWd9Xv Health Research Board (HRB) HSE Research and Development University College Cork HRB Clinical Research Facility - University College Cork

🗣️ Highlighting Clinical Trials & GDPR in the Oireachtas Last Thursday, Denis Naughten TD posed critical questions in the Oireachtas Leaders’ Questions about clinical trials, GDPR issues, patient needs, and Ireland's attractiveness as a trial destination. His insightful approach brought important visibility to the challenges and opportunities within our sector, underscoring the need for continued dialogue and action on GDPR as it impacts clinical trials. We encourage all members and supporters to watch this vital discussion, and we sincerely thank Denis for his support in highlighting these issues. 📽️ Watch here: https://lnkd.in/ek2hiSAj #ClinicalTrials #GDPR #LeadersQuestions #HealthcarePolicy

Join Cancer Trials Ireland, LACOG, and SLACOM as they explore the profound impact of climate change on cancer care worldwide. This session will feature global perspectives on how environmental changes are affecting cancer treatment and strategies to adapt healthcare systems accordingly. Date: November 13, 2024 Time: 15:30 - 17:00 GMT Location: Virtual Understand the intersection of climate change and cancer care. Register now >> https://bit.ly/3BXcPXs #LGCW2024 #LondonGlobalCancerWeek #ClimateChange #CancerCare #GlobalHealth Cancer Trials Ireland LACOG - Latin American Cooperative Oncology Group #Slacom Oncology Advocates United for Climate and Health - International

Well done Brendan Palmer and all, excellent talks. 

Last Thursday, TD Denis Naughten pose questions to the Oireachtas in Leaders’ Questions about clinical trials, and specifically the Cancer Trials Ireland GDPR position paper (Available here: https://lnkd.in/edt9afrr)   Very much worth a watch: https://lnkd.in/ek2hiSAj   #clinicaltrials #research

The clinical research community can learn about inclusive clinical trials through a dedicated workshop developed within the context of the Sensitise project. Stay tuned for workshop details. https://lnkd.in/erh-YQfm HRB Clinical Research Facility - University College Cork, HRB National Clinical Trials Office (NCTO), The School of Public Health UCC,UCC Medicine and Health, Trial Forge, ECRIN (European Clinical Research Infrastructure Network), Faculty of Medicine, Masaryk University, CZECRIN #inclusiveclinicaltrial, #DEI, #training, #trialdesign

Really enjoyed the Patient Focused Research in University College Cork Symposium today organised by Brendan Palmer from the HRB Clinical Research Facility - University College Cork Here are my takeaways from the day to apply to the Health Research Board (HRB) funded MaxSBF project to Maximise Support for Breastfeeding in Ireland: 1. Not all data needs to be anonymised, some contributors may want their name preserved for the records. 2. People want us to use their data, and significant work has been done to make that possible and safe. 3. Networking is essential, there is a big difference between reading a document and talking to the person who runs a service. 4. Consult your local friendly statistician early and often. 5. The food/snacks were awesome.