Cortical Studios

The NF-κB pathway controls a variety of genes that impact the development and progression of multiple myeloma. Some treatments that increase inhibition of NF-κB can result in the death of multiple myeloma cells. This is a segment from one of the two Mode of Action (MoA) videos we have produced for Celgene / Celgene Pharma / Bristol Myers Squibb. “Amazing at executing on the vision far beyond our expectations giving our concept life and enormous educational impact." Jorge Mouro - Scientific Director For any questions regarding animation or illustration, please don’t hesitate to contact us. We would love to help translate your scientific concepts! https://lnkd.in/eR4pcXMk www.corticalstudios.com Cortical Studios Glow Studio - Let’s illuminate your science together.

Some extra love for our free scientific images service, available under the creative commons license (creativecommons.org). Feel free to adjust them for commercial and educational use. They are great for companies and for academic purposes. Our main focus is creating custom mode of action (MoA) animations (and illustrations), but we also hope to enhance communication in the life sciences by providing this free resource. While we would appreciate being credited (by linking our URL or tagging #corticalstudios and #glowmedical), it is not required. Visit https://lnkd.in/eeNupedB to download the images. Feel free to share or tag someone who could benefit from these images. They are perfect for scientists, educators, students, or for use on your company's website. Cortical Studios Glow Studio - Let's illuminate your science together. www.corticalstudios.com Adding some clients and academic/commercial places/people where this might be of interest for: UvA, VUmc School of Medical Sciences, VUmc Ziekenhuis, Erasmus MC, Erasmus University Rotterdam, BioPartner Leiden, Smart Health Amsterdam (part of Amsterdam AI) , Leiden University, Leiden University Medical Center, UMC Utrecht, Sandra Migchielsen, Jurgen Seppen, New Scientist, MATTER, HITLAB, LifeHub UK, JLABS, Bayer G4A, Massachusetts Institute of Technology, Stanford University, Harvard University, Jim Jansen, Erik Scherder, IndieBio, Fierce Biotech, Olga Karpus. #freeimages  #freevisuals  #sciart  #medicalillustrations  #cellillustration

The proteasome is a protein complex that breaks down ubiquitin-tagged proteins through a process called proteolysis, which splits peptide bonds. In multiple myeloma, too much paraprotein leads to stress in the endoplasmic reticulum. The proteasome and thioredoxin system help manage this stress and keep multiple myeloma cells from dying. This scene is part of one of the two Mode of Action (MoA) films we've created for Celgene Pharma Celgene / Bristol Myers Squibb. “Amazing at executing on the vision far beyond our expectations giving our concept life and enormous educational impact." Jorge Mouro - Scientific Director For any questions regarding animation or illustration, please don’t hesitate to contact us. We would love to help translate your scientific concepts! https://lnkd.in/eR4pcXMk www.corticalstudios.com Cortical Studios Glow Studio - Let’s illuminate your science together.

For each project, we collaborate closely with our clients to discover a style that perfectly aligns with their company and technology. In this brief compilation, you'll see some of the graphical styles related to blood that we've developed for different clients. We've just wrapped up a major animation project (can't wait to share it soon!) that features several blood scenes. For any questions regarding animation or illustration, please don’t hesitate to contact us. We would love to help translate your scientific concepts! https://lnkd.in/eR4pcXMk www.corticalstudios.com Cortical Studios Glow Studio - Let’s illuminate your science together. Ronald Van Vemden Sicco de Vries Lisa Sove Freddy Peters Pieter van Lier Verseon BennuBio, Inc. Susan Blumenthal

This week is Mental Illness Awareness Week. We’ve had the opportunity to collaborate with life sciences companies to create Mode of Action films for new pharmacological treatments for mental illnesses. Additionally, we worked on several television shows, providing animations to support Prof. Dr. Erik Scherder in explaining the brain's functions and the various disorders that can occur. Thank you to everyone who helped make these projects possible: Erik Scherder, Lundbeck, MediaLane, Sicco de Vries, Ronald Van Vemden, Frans Millenaar, Dr Els van der Helm, Patricia Greven, Neeltje Bollen, Anna Bosscher and Steph Nigten.

Our YouTube channel is growing fast! We’re thrilled to have won a silver YouTube award, and our subscribers and views keep rising. A special highlight is our Mitochondria film, which is nearing 5 million views! Watch it here: https://lnkd.in/djH8PbZ Please feel free to have a look at our channel: https://lnkd.in/g94ziSB8 Sicco de Vries, Freddy Peters, Pieter van Lier, Ronald Van Vemden Cortical Studios - Let's illuminate your science together. www.corticalstudios.com #youtube #youtube100k #youtubesilveraward #viral #100k #100ksubscibers #modeofactionanimation #moaanimations #moa #mechanismofaction #medicalillustration #modeofaction #moaillustration #moaanimation #medicalanimation #scienceillustration #3dillustration #3danimation #medical3dillustration #corticalstudios #glowstudio #animationilluminatesscience

We are excited to showcase our animal health film, "CLOSTAT, a Novel Probiotic", on World Animal Day. Kemin Industries commissioned Cortical Studios to create a film that details the mechanism of action of CLOSTAT. CLOSTAT contains a proprietary, patented bacterial strain of Bacillus subtilis, PB6. PB6 is a unique, naturally occurring spore-forming microorganism. Kemin identified and selected the specific strain of PB6 because it secretes an active substance that helps maintain the balance of microflora in the intestinal tract of poultry and livestock. In the International Television & Film Competition New York Festivals, the film won a gold medal in the category Instruction & Education. Besides a gold medal, the film also won a bronze medal in the category Animation. In addition, it was listed as finalist at the Global Awards, with their special focus on science and health care. Freddy Peters Pieter van Lier Ronald Van Vemden Lisa Sove Interested in developing an animation? Let's illuminate your science together: www.corticalstudios.com #WorldAnimalDay #moa

As October is Vision Awareness Month, we would like to present one of the three films we have created for procornea / CooperVision about myopia and Ortho-K, titled “What is Ortho-K”. In an alarmingly increasing number of myopia cases, orthokeratology or Ortho-K is used as a correction method. Developing high myopia can lead to serious complications such as glaucoma, cataracts, and retinal detachment. Research has shown that orthokeratology can slow down the progression of myopia in children. The key factor in this process is the light that strikes the outer regions of the retina when the eyes are in focus. With glasses, regular contact lenses, and refractive surgery, peripheral light is focused behind the outer retina, potentially increasing the risk of myopic progression. In contrast, Ortho-K lenses focus the light in front of the outer retina, which appears to slow down the development of myopia and reduce the risk of future complications for children. Orthokeratology is a safe and convenient solution that can correct myopia effectively in both adults and children. For any questions regarding animation or illustration, please don’t hesitate to contact us. We would love to help translate your scientific concepts! https://lnkd.in/eR4pcXMk www.corticalstudios.com Cortical Studios Glow Studio - Let’s illuminate your science together.

In honor of Blood Cancer Awareness Month in September, we are sharing segments of two Mode of Action (MoA) animations created for Celgene Pharma / Bristol Myers Squibb. These animations highlight drugs that assist in treating the rare blood cancer Multiple Myeloma, a group of malignant plasma cell neoplasms known for uncontrolled proliferation in the bone marrow. “Working with Cortical Studios and Glow Studio was an amazing experience. We had a vision to animate very complicated biochemical processes that helped describe hypothetical mechanisms of synergistic effects of combination cancer treatment. Cortical Studios and Glow Studio worked with us not only to animate the ideas, but to build the project from the beginning of the idea. They advised us on how to best incorporate certain aspects including keeping the video short, and leveraging high quality 3-D imagery that can only be described as magical rendering of cellular and molecular processes. Cortical Studios and Glow Studio also supported the team as needed to ensure internal stakeholders were fully included in the development process. In short, the teams at Cortical Studios and Glow Studio were amazing at executing on the vision far beyond our expectations giving our concept life and enormous educational impact." — Jorge Mouro - Scientific Director  Celgene Please feel free to contact us with any questions regarding animation or illustration. We would love to help translate your science! https://lnkd.in/eR4pcXMk www.corticalstudios.com Cortical Studios Glow Studio - Let’s illuminate your science together. #bloodcancer #BristolMyersSquibb #MM #multiplemyeloma #celgene  #modeofactionanimation #moaanimations #mechanismofaction #scientificillustration #medicalillustration #modeofaction  #moaillustration #moaanimation  #medicalanimation #scienceillustration #3dillustration

The fluidity of the cell membrane, with a highly dynamic movement of proteins, is beautifully captured in the footage created by creative director Sicco de Vries. Our partnership, established in 2015, has been recognized with a range of awards including a Global Award at The Global Awards, multiple Gold Awards at New York Festivals, and several Telly Awards. Now, with our YouTube Silver Award added to our list, we are excited to showcase our work to a diverse audience, ranging from those with no scientific background to students, medical specialists, and scientists (https://lnkd.in/eSXKkhZX at 102k subscribers). Our expertise lies in Mode of Action animations and Mode of Disease animations. Cortical Studios Glow Studio - Let's illuminate your science together. Please feel free to contact us with any questions regarding a potential animation project. We would love to help translate your science! https://lnkd.in/eR4pcXMk