LUMICKS

"The C-trap lowers the barrier for accessing single-molecule imaging, making it possible to understand dynamics.” says Dr. Lori Passmore. She and Dr. David Rueda published a #Nature article showcasing how the C-Trap technology is transforming our understanding of DNA-protein interactions. Check out our digest of the publication here: https://lnkd.in/dy5AU4BY

Interested in getting some cell avidity data this year? Reach out about our Avidigo high throughput Cell Avidity Services: Accelerating preclinical immunotherapy development by enhancing candidate selection with complete binding characterization Fully characterize your cell therapy constructs with Avidigo by looking at potency, sensitivity, kinetics and safety! 📊🚀 https://bit.ly/3UoW9OW

Ever thought about braiding DNA? With a C-Trap, it’s not just possible—it’s doable! 🧬 Curious to see how? Follow us and stay tuned for our tutorial! Movie credit: Ian Hickson lab #DNAbraid#singlemolecule#lumicks#CTrap

⍰ What is an immune synapse and why is it relevant for cell therapy? (A bit of micro-learning for your Wednesday, chopped up into small pieces of digestible information.) An immune synapse is the interface between an antigen-presenting cell or target cell and a lymphocyte or natural killer cell. It’s formed in a highly stable, organized manner. This interface includes T cell receptor (TCR) clustering, checkpoint or costimulatory receptor binding, cell-cell adhesion proteins, and more. Proper formation of the immune synapse between a cancer cell and an effector cell is crucial. It initiates immune cell activation, sustains proliferation, and increases cytokine secretion against cancer cells. The organization of the TCR and molecules at the binding site impacts immune cell function. And investigating the synaptic structure helps researchers understand the mechanism of action. This leads to better predictions of immunotherapy efficacy. 👉 Learn about immune synapses and more on our cell avidity resource page on lumicks.com

“It’s probably the only way!“ Wonder how Prof. David Rueda describe his dynamic single-molecule research? Watch the full video:

Will you be attending the AACR Special Conference in Cancer Research: Tumor Immunology and Immunotherapy this weekend in Boston? Our incredible Field Scientist and Customer Success extraordinaire, Dr. Song-My Hoang will be presenting her poster during Session B on Sunday October 20th. Be sure to stop by and hear more about our latest data and publications with our Cell Avidity technology and learn more about our high through-put services, Avidigo!

We're thrilled to share groundbreaking research from our customer! Latest study from Gijs Wuite's lab unveils the 'memory' function of enzymes during DNA replication, providing new insights in understanding replication process and opening new doors for therapeutic advancements. Read our digest here: https://bit.ly/3U9YbTb

We are so proud to announce our first Cell Avidity Center of Excellence, located in Dr. Sizun Jiang Lab. We look forward to all the brilliant research that comes out of his lab and future collaborations. Interested in getting a cell avidity project started in the Boston area? Feel free to reach out to us and we’d be happy to connect with you. #cellavidity #collaborations #immunology #immunotherapy

Did you join the live webinar with Prof. David Rueda several weeks ago? You can now watch the on-demand session anytime, anywhere. Dive into Prof. Rueda's fascinating insights on the Fanconi anemia pathway and its crucial role in DNA repair. 🎥 Watch Now: https://bit.ly/400ubwz Don't miss this chance to expand your knowledge on groundbreaking scientific research!

Have you ever imagined braiding DNA strands? With a C-Trap, you can! 🧬 Want to learn how? Follow us and stay tuned for our upcoming tutorial! Movie credit: Ian Hickson lab #DNAbraid #SingleMolecule #LUMICKS #CTrap