Selvita

We are excited to announce the enhancement of our screening capabilities with the addition of the FlexStation 3! This versatile technology enables us to offer an expanded range of precise cell-based and biochemical assays, ideal for various applications including oncology research. Our strengthened capabilities include real-time kinetic analyses of GPCR activity, ion channel modulation, enzyme kinetics, and biomarker detection, using highly sensitive fluorescence and luminescence readouts. FlexStation 3's precise liquid handling ensures reproducible results, providing robust support for hit identification, lead optimization, and mechanistic studies. Our expert team is ready to customize these assays to meet your specific research needs, providing tailored support at every step of your drug discovery project. Let's collaborate to take your research to the next level! #drugdiscovery #HTS #oncology #screening #flexstation #biochemical #gpcr #biomarkers

Serdecznie zapraszamy na spotkanie z Zarządem Selvita S.A. poświęcone podsumowaniu 2024 roku oraz dalszym planom i perspektywom Spółki. Transmisja będzie dostępna pod adresem: https://lnkd.in/e-nwYMnR

Are you ready to take the next step in your career? Whether you're a recent graduate searching for your first job or an experienced professional looking for new challenges, we have something for you! Meet Pamela Rojek and Lidia Wicher from our recruitment team at the Jagiellonian University Job Fairs at Auditorium Maximum in Krakow. They’re here to chat, answer your questions, and help you discover exciting career opportunities. Come by, say hi, grab our unique gadgets, and let’s discuss how you can grow with us. See you there! #SelvitaCareers #Recruitment

Reminder: Learn from the experts! Developing PROTACs for oral delivery comes with significant ADME challenges. PBPK modeling provides a data-driven approach to overcome these obstacles. Join our experts David Cebrián and Simone Esposito as they share real-world case studies on how PBPK modeling can optimize PROTAC drug discovery. 📅 April 2 | 5 PM CET / 11 AM ET Don’t wait—register today!

Discover the latest publication to which our AI expert Joerg Wichard contributed: ‘Data-driven federated learning in drug discovery with knowledge distillation.' This article introduces FLuID, a novel approach that allows pharmaceutical companies to share data securely while maintaining confidentiality, accelerating the development of AI models in drug discovery. Read the full publication here: https://lnkd.in/e2zQ-Brt This week, Jörg will be at the KNIME Spring Summit in Berlin, where on Thursday, March 20 at 10:40 AM, he will give a talk on: "Accelerating Drug Discovery: ML Model Deployment and Lab Process Automation with KNIME". It’s a great opportunity to meet him and learn more about Selvita AI solutions in drug discovery! If you want to explore more of our scientists' research, visit our website: https://lnkd.in/eDArSGNz #DrugDiscovery #AI #ML #MachineLearning #KNIME #AIinScience

Aging is inevitable—but disability doesn’t have to be. In the UK, by the age of 70–74, one in three women and one in four men are classified as disabled. With populations aging rapidly, the need for scientific breakthroughs in healthy aging has never been greater. If you didn't have a chance yet, read our blog post to learn more about aging and how science comes together to make an impact for the future: https://lnkd.in/eT8Nwg7U #drugdiscovery #aging #ageing #disability #heatlhyaging #longevity

Antibody characterization is key to ensuring therapeutic success! Our team performed in-depth characterization of Rituximab, a CD20-targeting monoclonal antibody used in oncology, to confirm its specificity, binding strength, and immune activation mechanisms. Using advanced techniques like BLI and flow cytometry we provided in-depth insights into its therapeutic potential. Read the whole case study prepared by our experts Małgorzata, Sonia, and Beata, here: https://lnkd.in/ebEiqbKQ If you want to learn more about our approach to antibody drug discovery and our capabilities in this area, visit our website: https://lnkd.in/eT8AqCAt #drugdiscovery #blog #casestudy #antibody #antibodies #oncology #rituximab

𝐂𝐚𝐧 𝐏𝐡𝐲𝐬𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥𝐥𝐲-𝐁𝐚𝐬𝐞𝐝 𝐏𝐡𝐚𝐫𝐦𝐚𝐜𝐨𝐤𝐢𝐧𝐞𝐭𝐢𝐜 (𝐏𝐁𝐏𝐊) 𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠 𝐨𝐩𝐭𝐢𝐦𝐢𝐳𝐞 𝐭𝐡𝐞 𝐩𝐨𝐭𝐞𝐧𝐭𝐢𝐚𝐥 𝐨𝐟 𝐏𝐑𝐎𝐓𝐀𝐂𝐬? Targeted protein degraders represent a novel approach to drug design, offering new therapeutic possibilities. However, their complex ADME properties pose serious obstacles to oral bioavailability. In our upcoming webinar, David Cebrián and Simone Esposito, our DMPK experts with over 30 combined years of experience, will discuss how PBPK modeling serves as a powerful tool to tackle these issues, providing a systematic, data-driven approach to optimizing drug properties. Through real-world case studies, they will demonstrate how modeling can bridge the gap between experimental data and clinical outcomes. 📅 April 2 | 5 PM CET / 11 AM ET Register today: https://lnkd.in/ePhncWWh #webinar #drugdiscovery #DMPK #TPD #PROTAC #PROTACs #PBPK #modeling #ADME

Join us at the KNIME Spring Summit in Berlin, March 18-20, 2025! On March 20, at 10:40 am, our experts Joerg and Fabrizio will present "Accelerating Drug Discovery: ML Model Deployment and Lab Process Automation with KNIME". We'll highlight how we use KNIME to: • Make Python-based ML models for QSAR and ADMET easily accessible through a unified API. • Streamline lab processes, improving efficiency and saving time and resources in the purification department. Don't miss out—check out the event details here: https://lnkd.in/eViCU-23 If you want to learn more about our AI solutions, visit our website: https://lnkd.in/evJnUggY #AI #ML #drugdiscovery #KNIME

Are you following our 𝐌𝐞𝐝𝐂𝐡𝐞𝐦 𝐄𝐬𝐬𝐞𝐧𝐭𝐢𝐚𝐥𝐬 series on YouTube? Today, we're excited to launch a brand-new episode focused on solubility - the first video on this key drug property. In this episode, our colleague Jakub dives into how solubility affects drug discovery and explores the crucial role of hydrogen bonds. Watch the episode now: https://lnkd.in/eegnVrWM Missed our earlier topics? Check out our playlist featuring previous episodes on lipophilicity and permeability: https://lnkd.in/eHPMhRgE Subscribe to our channel and stay updated with our latest scientific insights! #MedicinalChemistry #MedChemEssentials #Solubility #DrugDiscovery #HydrogenBonds #Permeability #Lipophilicity