Selvita

Discover the latest publication to which our AI expert Joerg Wichard contributed: ‘Data-driven federated learning in drug discovery with knowledge distillation.' This article introduces FLuID, a novel approach that allows pharmaceutical companies to share data securely while maintaining confidentiality, accelerating the development of AI models in drug discovery. Read the full publication here: https://lnkd.in/e2zQ-Brt This week, Jörg will be at the KNIME Spring Summit in Berlin, where on Thursday, March 20 at 10:40 AM, he will give a talk on: "Accelerating Drug Discovery: ML Model Deployment and Lab Process Automation with KNIME". It’s a great opportunity to meet him and learn more about Selvita AI solutions in drug discovery! If you want to explore more of our scientists' research, visit our website: https://lnkd.in/eDArSGNz #DrugDiscovery #AI #ML #MachineLearning #KNIME #AIinScience

Aging is inevitable—but disability doesn’t have to be. In the UK, by the age of 70–74, one in three women and one in four men are classified as disabled. With populations aging rapidly, the need for scientific breakthroughs in healthy aging has never been greater. If you didn't have a chance yet, read our blog post to learn more about aging and how science comes together to make an impact for the future: https://lnkd.in/eT8Nwg7U #drugdiscovery #aging #ageing #disability #heatlhyaging #longevity

Antibody characterization is key to ensuring therapeutic success! Our team performed in-depth characterization of Rituximab, a CD20-targeting monoclonal antibody used in oncology, to confirm its specificity, binding strength, and immune activation mechanisms. Using advanced techniques like BLI and flow cytometry we provided in-depth insights into its therapeutic potential. Read the whole case study prepared by our experts Małgorzata, Sonia, and Beata, here: https://lnkd.in/ebEiqbKQ If you want to learn more about our approach to antibody drug discovery and our capabilities in this area, visit our website: https://lnkd.in/eT8AqCAt #drugdiscovery #blog #casestudy #antibody #antibodies #oncology #rituximab

𝐂𝐚𝐧 𝐏𝐡𝐲𝐬𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥𝐥𝐲-𝐁𝐚𝐬𝐞𝐝 𝐏𝐡𝐚𝐫𝐦𝐚𝐜𝐨𝐤𝐢𝐧𝐞𝐭𝐢𝐜 (𝐏𝐁𝐏𝐊) 𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠 𝐨𝐩𝐭𝐢𝐦𝐢𝐳𝐞 𝐭𝐡𝐞 𝐩𝐨𝐭𝐞𝐧𝐭𝐢𝐚𝐥 𝐨𝐟 𝐏𝐑𝐎𝐓𝐀𝐂𝐬? Targeted protein degraders represent a novel approach to drug design, offering new therapeutic possibilities. However, their complex ADME properties pose serious obstacles to oral bioavailability. In our upcoming webinar, David Cebrián and Simone Esposito, our DMPK experts with over 30 combined years of experience, will discuss how PBPK modeling serves as a powerful tool to tackle these issues, providing a systematic, data-driven approach to optimizing drug properties. Through real-world case studies, they will demonstrate how modeling can bridge the gap between experimental data and clinical outcomes. 📅 April 2 | 5 PM CET / 11 AM ET Register today: https://lnkd.in/ePhncWWh #webinar #drugdiscovery #DMPK #TPD #PROTAC #PROTACs #PBPK #modeling #ADME

Join us at the KNIME Spring Summit in Berlin, March 18-20, 2025! On March 20, at 10:40 am, our experts Joerg and Fabrizio will present "Accelerating Drug Discovery: ML Model Deployment and Lab Process Automation with KNIME". We'll highlight how we use KNIME to: • Make Python-based ML models for QSAR and ADMET easily accessible through a unified API. • Streamline lab processes, improving efficiency and saving time and resources in the purification department. Don't miss out—check out the event details here: https://lnkd.in/eViCU-23 If you want to learn more about our AI solutions, visit our website: https://lnkd.in/evJnUggY #AI #ML #drugdiscovery #KNIME

Are you following our 𝐌𝐞𝐝𝐂𝐡𝐞𝐦 𝐄𝐬𝐬𝐞𝐧𝐭𝐢𝐚𝐥𝐬 series on YouTube? Today, we're excited to launch a brand-new episode focused on solubility - the first video on this key drug property. In this episode, our colleague Jakub dives into how solubility affects drug discovery and explores the crucial role of hydrogen bonds. Watch the episode now: https://lnkd.in/eegnVrWM Missed our earlier topics? Check out our playlist featuring previous episodes on lipophilicity and permeability: https://lnkd.in/eHPMhRgE Subscribe to our channel and stay updated with our latest scientific insights! #MedicinalChemistry #MedChemEssentials #Solubility #DrugDiscovery #HydrogenBonds #Permeability #Lipophilicity

Reminder: Our Webinar is Happening TODAY! Don’t miss out on this opportunity to explore the world of biologics discovery and how AI is transforming the field! If you're eager to learn more, there's still time to register and join us later today. Dr. Piotr Mamczur, PhD (Selvita) and Dr. Maciej Jasinski, PhD (Ardigen) will explore the challenges and opportunities at the frontier of AI in biologics discovery, sharing practical strategies that are already driving meaningful impact. Register here: https://lnkd.in/ewbiMuJi #biologics #drugdiscovery #antibodies #AI

𝗦𝗲𝗹𝘃𝗶𝘁𝗮 𝗢𝗽𝗲𝗻 𝗗𝗮𝘆𝘀 – 𝗥𝗲𝗴𝗶𝘀𝘁𝗿𝗮𝘁𝗶𝗼𝗻 𝗦𝘁𝗶𝗹𝗹 𝗢𝗽𝗲𝗻! Curious about a career in biotech? Don’t miss the chance to visit Selvita during our 𝗢𝗽𝗲𝗻 𝗗𝗮𝘆𝘀 and get a behind-the-scenes look at our work! 📍 𝗞𝗿𝗮𝗸𝗼𝘄 – March 14th 📍 𝗣𝗼𝘇𝗻𝗮𝗻 – March 20th 📍 𝗭𝗹𝗼𝘁𝗻𝗶𝗸𝗶 – March 21st Spots are limited – sign up now at https://lnkd.in/dyWD2dmm

Join us at the 2nd Animal Models of Cancer Conference and explore our latest research! Don’t miss our poster "Orthotopic colon cancer model: important role of the microenvironment in in vivo cancer research" (#19), presented during the dedicated poster session on Friday, February 28, from 17:15 – 19:30. Meet the poster co-author Martyna Śniegocka to discuss how tumor microenvironmental factors influence drug distribution and cancer biology, highlighting the importance of orthotopic models in translational oncology research. Additionally, connect with both her and Magdalena Kieltyka to explore how our in vivo services can support your drug discovery efforts. At Selvita we offer a comprehensive range of in vitro and in vivo assays, including cytotoxicity, apoptosis, and biomarker analysis. With state-of-the-art facilities and tailored solutions, we provide high-quality, reliable data to advance your research. We look forward to connecting with you! #CancerResearch #AnimalModels #InVivo #PrecisionOncology #PreclinicalResearch #AMC25

The global population is ageing, and while life expectancy has steadily increased, so has the number of years spent in poor health. At Selvita, we believe that science holds the key to reversing this trend. In our latest blog post by Kirsty Winn, we explore: ✅ lifestyle and medical approaches to healthy aging ✅ challenges in managing age-related diseases ✅ impact of polypharmacy and multimorbidity ✅ latest advances in longevity research Read the full blog post and discover how science is redefining the way we age: https://lnkd.in/e-kR_Ygh ❔What do you think is the most promising approach to improving healthspan?