bit.bio

New ioCells Product Hub | Find the right cells - fast! 🔗 Discover the latest addition to our website. https://lnkd.in/emUpXGSc A one-stop destination to quickly find the opti-ox powered human iPSC-derived cells you need for your experiments. With intuitive filters by cell type, disease area, or genome modification, our hub makes it simple to pinpoint the tools that match your research goals. From Alzheimer’s and ALS to CRISPR-Ready ioCells, everything is organised for scientists - so you can focus on advancing your work. Simplify your search. Discover ioCells. #cells #optiox #ioCells #launch #humancells #research #science #DrugDevelopment #DrugDiscovery

Happy St. Patrick's Day! 🍀 GFP ioMicroglia are engineered with built-in green fluorescence - helping you visualise, track, and isolate microglia in complex co-cultures. Discover how these cells can support your research https://hubs.ly/Q03bTMlk0 #StPatricksDay #GFP #ioMicroglia #iPSC #Neuroscience #CellBiology #optiox #ioCells

Attending #SOT2025 in Orlando? Let’s talk about tackling key challenges in predicting drug metabolism and hepatotoxicity. Thomas Brown and Sebastian Fiedler will be at SOT, ready to discuss the latest data on deterministically programmed human iPSC-derived hepatocytes and how these cells can support toxicology studies. Book a meeting here: https://hubs.ly/Q03bsCYN0 Not attending SOT? Let’s connect another time, we are always keen to hear your perspective. Get in touch https://hubs.ly/Q03bsD8x0 #DrugDiscovery #LiverToxicology #DILI #ToxicologyResearch #iPSC #optiox #ioCells

Team bit.bio took on the Cambridge Half Marathon this weekend! From start to finish, it was an incredible experience, pushing limits, supporting each other, and enjoying the energy of the city. A huge well done to everyone who ran, cheered, and made this event such a great team effort! #CambridgeHalfMarathon #TeamBitBio #StrongerTogether

Today, on International Womens Day, we celebrate the brilliant, driven, and passionate women of bit.bio for their dedication, expertise, and impact. Science thrives on diverse perspectives, and the incredible women across our science, commercial, and operations teams play a crucial role in driving our mission forward every day. The gallery below highlights just some of them, alongside our interim CEO, who fully supports the cause (and knows that today, he’s not the main event!). #IWD2025 #WomenInScience #InternationalWomensDay

For scientists developing therapies for ALS, working with human iPSC-derived motor neurons often means battling clumpy cell cultures, which make electrophysiology assays, transfections, and imaging difficult. As the cells aggregate, they can detach over time, preventing long-term studies. All leading to poor assay performance and inconsistent, unreliable results. bit.bio's ioMotor Neurons and genetically matched disease models remove these technical barriers. ✅ No clumping – ioMotor Neurons form a homogenous culture meaning higher success rates for transfections, clearer imaging and reduced noise in electrophysiology assays. ✅ Physiologically relevant – Defined spinal motor neuron identity (cervical region) indicated by HOX gene signature and key motor neuron specific marker expression ISL2 and the cholinergic marker ChAT. ✅ Consistent – ioMotor Neurons are powered by opti-ox™, ensuring unparalleled consistency across lots, days and labs, empowering scientists with confidence in experimental reproducibility. The cells provide scientists with defined, functional lower motor neurons, enabling them to build physiological relevance into their research and helping bridge translational gaps in motor neuron disease research. With ready-to-use human iPSC-derived ioMotor Neurons, you can focus on discovery, not technical challenges. Try ioMotor Neurons today and see the difference. https://hubs.ly/Q039H0430 #research #DrugDiscovery #optiox #ioCells #science #CellCulture #MND #ALS #MotorNeurons #PatchClamp #MEA

Are you a detail-oriented logistics individual looking to make an impact in a fast-paced biotech environment? Join #bit.bio as a 𝗟𝗼𝗴𝗶𝘀𝘁𝗶𝗰𝘀 𝗧𝗲𝗰𝗵𝗻𝗶𝗰𝗶𝗮𝗻 ⚙️ As a 𝗟𝗼𝗴𝗶𝘀𝘁𝗶𝗰𝘀 𝗧𝗲𝗰𝗵𝗻𝗶𝗰𝗶𝗮𝗻, you will be responsible for the efficient management of incoming goods and ensuring stock levels meet operational needs, your work will directly support our operations running smoothly. We’re looking for a proactive and organised team player with: - Experience in a logistics, warehouse, or supply chain role (biotech/pharma experience is preferred). - Strong attention to detail and problem-solving skills. - Ability to work in a fast-paced environment and manage multiple priorities. - Knowledge and experience using computer software including ERP system. -Comfort with this role involving standing 60% to 100% of the time and lifting heavy weights. To apply, visit our careers page at https://hubs.ly/Q039KYR50 #Hiring #SupplyChainJobs #BiotechJobs #CambridgeJobs #bitbio #JoinUs #MakeAnImpact

Join us for an insightful webinar with 4 experts from Charles River Laboratories, Axion BioSystems, Sartorius, and bit.bio. Register here https://hubs.ly/Q039f7YJ0 Speakers will discuss real-world applications of bit.bio's deterministically programmed human iPSC-derived ioCells across key stages of early-stage drug discovery - target identification, assay development, disease modelling, and toxicology studies. You will learn about: -Quick and easy perturbation of gene expression for target ID and validation in hiPSCs -Assay development and live-cell imaging for neuroinflammation studies using neuronal and glial co-cultures -Disease modelling in excitatory neurons with ALS-associated phenotypes using HT-MEA Register now https://hubs.ly/Q039f7YJ0 #research #DrugDiscovery #StemCells #DiseaseModelling #CRISPRscreening #optiox #ioCells #CNS #NeuroDegeneration

NEW ioCELLS™ ALERT! bit.bio expands CRISPR-Ready ioCells range, enabling precise gene perturbation in human iPSC-derived cells. For the first time, researchers can perform CRISPR activation (CRISPRa), interference (CRISPRi), and knockout (CRISPRko) experiments in defined, consistent, and scalable human iPSC-derived cells. These cells already express Cas9 nuclease or dCas9 variants, eliminating months of cell engineering and optimisation of differentiation protocols. The newly launched CRISPRa-Ready and CRISPRi-Ready ioGlutamatergic Neurons join the existing CRISPRko-Ready ioCells, completing our range of functional genomics tools for: -Precise perturbation of gene expression -Large-scale CRISPR screens -Target identification and validation in neurodegenerative drug discovery With optimised culture conditions and guide RNA delivery protocols, CRISPR-Ready ioCells allow researchers to generate results in a matter of days. Read the press release: https://hubs.ly/Q038_kXf0 #CRISPR #FunctionalGenomics #DrugDiscovery #ioCells #optiox

Watch bit.bio’s human iPSC-derived ioAstrocytes in action, captured with Nanolive’s cutting-edge technology! These astrocytes don’t just support—they actively engulf and digest debris, helping maintain brain health. In this timelapse, watch red fluorescent particles as they’re phagocytosed over 24 hours, highlighting their powerful phagocytic abilities. This process is essential for neural circuit refinement, clearing dead cells, and supporting brain recovery, especially when microglial function is compromised. Shoutout to bit.bio for sharing these incredible images! Learn more about Nanolive’s imaging tech and bit.bio’s ioAstrocytes—links below ⬇️ #innovation #health #technology