bit.bio’s cover photo
bit.bio

bit.bio

Biotechnology Research

Cambridge, Cambridgeshire 20,804 followers

The Cell Coding Company

About us

bit.bio is an award-winning human synthetic biology company - our mission: coding cells for novel cures. We have developed an end-to-end platform for the creation of any human cell type. With our cutting-edge and patent-protected opti-ox precision cell programming technology, we can deterministically program human iPSCs into a chosen cell identity with unprecedented biological consistency at an industrial scale, and approximately 10 times faster than conventional methods. Our platform has the potential to unlock a new generation of medicines. Our io Cells research products provide scientists access to highly characterised, consistent, scalable human cells that enable research and drug discovery teams to accelerate their experimental timelines and reduce experimental variability, providing an important alternative to traditional workflows. We are also leveraging our platform to build a pipeline of txCells for cell therapies. To achieve our goals, we have assembled a team of pioneers in stem cell biology, cell programming, mathematical modelling and cell therapy. We are empirical, highly ambitious and driven by a shared vision. Collaboration is at the heart of bit.bio. Join us on our journey. For more information on bit.bio’s trademarks, visit www.bit.bio/trademarks

Website
https://bit.bio
Industry
Biotechnology Research
Company size
51-200 employees
Headquarters
Cambridge, Cambridgeshire
Type
Privately Held
Founded
2016
Specialties
biotechnology, cell type, life science, pharmaceutical drug discovery, High throughput screening, and cell therapy

Locations

  • Primary

    The Dorothy Hodgkin Building

    Babraham Research Campus

    Cambridge, Cambridgeshire CB22 3FH, GB

    Get directions

Employees at bit.bio

Updates

  • View organization page for bit.bio

    20,804 followers

    New ioCells Product Hub | Find the right cells - fast! 🔗 Discover the latest addition to our website. https://lnkd.in/emUpXGSc A one-stop destination to quickly find the opti-ox powered human iPSC-derived cells you need for your experiments. With intuitive filters by cell type, disease area, or genome modification, our hub makes it simple to pinpoint the tools that match your research goals. From Alzheimer’s and ALS to CRISPR-Ready ioCells, everything is organised for scientists - so you can focus on advancing your work. Simplify your search. Discover ioCells. #cells #optiox #ioCells #launch #humancells #research #science #DrugDevelopment #DrugDiscovery

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  • View organization page for bit.bio

    20,804 followers

    Attending #SOT2025 in Orlando? Let’s talk about tackling key challenges in predicting drug metabolism and hepatotoxicity. Thomas Brown and Sebastian Fiedler will be at SOT, ready to discuss the latest data on deterministically programmed human iPSC-derived hepatocytes and how these cells can support toxicology studies. Book a meeting here: https://hubs.ly/Q03bsCYN0 Not attending SOT? Let’s connect another time, we are always keen to hear your perspective. Get in touch https://hubs.ly/Q03bsD8x0 #DrugDiscovery #LiverToxicology #DILI #ToxicologyResearch #iPSC #optiox #ioCells

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  • View organization page for bit.bio

    20,804 followers

    Today, on International Womens Day, we celebrate the brilliant, driven, and passionate women of bit.bio for their dedication, expertise, and impact. Science thrives on diverse perspectives, and the incredible women across our science, commercial, and operations teams play a crucial role in driving our mission forward every day. The gallery below highlights just some of them, alongside our interim CEO, who fully supports the cause (and knows that today, he’s not the main event!). #IWD2025 #WomenInScience #InternationalWomensDay

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  • For scientists developing therapies for ALS, working with human iPSC-derived motor neurons often means battling clumpy cell cultures, which make electrophysiology assays, transfections, and imaging difficult. As the cells aggregate, they can detach over time, preventing long-term studies. All leading to poor assay performance and inconsistent, unreliable results. bit.bio's ioMotor Neurons and genetically matched disease models remove these technical barriers. ✅ No clumping – ioMotor Neurons form a homogenous culture meaning higher success rates for transfections, clearer imaging and reduced noise in electrophysiology assays. ✅ Physiologically relevant – Defined spinal motor neuron identity (cervical region) indicated by HOX gene signature and key motor neuron specific marker expression ISL2 and the cholinergic marker ChAT. ✅ Consistent – ioMotor Neurons are powered by opti-ox™, ensuring unparalleled consistency across lots, days and labs, empowering scientists with confidence in experimental reproducibility. The cells provide scientists with defined, functional lower motor neurons, enabling them to build physiological relevance into their research and helping bridge translational gaps in motor neuron disease research. With ready-to-use human iPSC-derived ioMotor Neurons, you can focus on discovery, not technical challenges. Try ioMotor Neurons today and see the difference. https://hubs.ly/Q039H0430 #research #DrugDiscovery #optiox #ioCells #science #CellCulture #MND #ALS #MotorNeurons #PatchClamp #MEA

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  • View organization page for bit.bio

    20,804 followers

    Are you a detail-oriented logistics individual looking to make an impact in a fast-paced biotech environment? Join #bit.bio as a 𝗟𝗼𝗴𝗶𝘀𝘁𝗶𝗰𝘀 𝗧𝗲𝗰𝗵𝗻𝗶𝗰𝗶𝗮𝗻 ⚙️ As a 𝗟𝗼𝗴𝗶𝘀𝘁𝗶𝗰𝘀 𝗧𝗲𝗰𝗵𝗻𝗶𝗰𝗶𝗮𝗻, you will be responsible for the efficient management of incoming goods and ensuring stock levels meet operational needs, your work will directly support our operations running smoothly. We’re looking for a proactive and organised team player with: - Experience in a logistics, warehouse, or supply chain role (biotech/pharma experience is preferred). - Strong attention to detail and problem-solving skills. - Ability to work in a fast-paced environment and manage multiple priorities. - Knowledge and experience using computer software including ERP system. -Comfort with this role involving standing 60% to 100% of the time and lifting heavy weights. To apply, visit our careers page at https://hubs.ly/Q039KYR50 #Hiring #SupplyChainJobs #BiotechJobs #CambridgeJobs #bitbio #JoinUs #MakeAnImpact

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  • Join us for an insightful webinar with 4 experts from Charles River Laboratories, Axion BioSystems, Sartorius, and bit.bio. Register here https://hubs.ly/Q039f7YJ0 Speakers will discuss real-world applications of bit.bio's deterministically programmed human iPSC-derived ioCells across key stages of early-stage drug discovery - target identification, assay development, disease modelling, and toxicology studies. You will learn about: -Quick and easy perturbation of gene expression for target ID and validation in hiPSCs -Assay development and live-cell imaging for neuroinflammation studies using neuronal and glial co-cultures -Disease modelling in excitatory neurons with ALS-associated phenotypes using HT-MEA Register now https://hubs.ly/Q039f7YJ0 #research #DrugDiscovery #StemCells #DiseaseModelling #CRISPRscreening #optiox #ioCells #CNS #NeuroDegeneration

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  • View organization page for bit.bio

    20,804 followers

    NEW ioCELLS™ ALERT! bit.bio expands CRISPR-Ready ioCells range, enabling precise gene perturbation in human iPSC-derived cells. For the first time, researchers can perform CRISPR activation (CRISPRa), interference (CRISPRi), and knockout (CRISPRko) experiments in defined, consistent, and scalable human iPSC-derived cells. These cells already express Cas9 nuclease or dCas9 variants, eliminating months of cell engineering and optimisation of differentiation protocols. The newly launched CRISPRa-Ready and CRISPRi-Ready ioGlutamatergic Neurons join the existing CRISPRko-Ready ioCells, completing our range of functional genomics tools for: -Precise perturbation of gene expression -Large-scale CRISPR screens -Target identification and validation in neurodegenerative drug discovery With optimised culture conditions and guide RNA delivery protocols, CRISPR-Ready ioCells allow researchers to generate results in a matter of days. Read the press release: https://hubs.ly/Q038_kXf0 #CRISPR #FunctionalGenomics #DrugDiscovery #ioCells #optiox

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  • bit.bio reposted this

    View profile for Noah Thyberg

    Cellular Analysis Specialist; Heart Transplant Recipient & Organ Donation Advocate

    Watch bit.bio’s human iPSC-derived ioAstrocytes in action, captured with Nanolive’s cutting-edge technology! These astrocytes don’t just support—they actively engulf and digest debris, helping maintain brain health. In this timelapse, watch red fluorescent particles as they’re phagocytosed over 24 hours, highlighting their powerful phagocytic abilities. This process is essential for neural circuit refinement, clearing dead cells, and supporting brain recovery, especially when microglial function is compromised. Shoutout to bit.bio for sharing these incredible images! Learn more about Nanolive’s imaging tech and bit.bio’s ioAstrocytes—links below ⬇️ #innovation #health #technology

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