Breast Cancer Now

It's wear it pink day! 🎉 Thank you to all the workplaces, friends, communities who are wearing it pink day. We’d love to hear what you’re up to! Please tag us in your photos and tell us how you’re taking part in this year’s #WearItPink 👇 However you’re doing it, by wearing pink you’re helping to fund life-changing breast cancer research and support. We can’t do it without you. From all of us at Breast Cancer Now, we’d like to say a HUGE thank you! 🎀💗 If you’re not able to take part you can still donate via the link below. https://lnkd.in/ecyeGfHE

On 9 and 10 October, law firms and chambers took part in the static bike challenge Tour de Law 2024 competing for the Tour de Law top spot whilst raising money for breast cancer research and support. So far, our amazing Tour de Law teams have raised a staggering £165,000! The money our teams raised will help us work towards a future where no one loses someone they love to breast cancer. Our Tour de Law 2024 champions are… Latham & Watkins LLP! The team cycled 868.19 kilometres over 2 days and reached an incredible fundraising total of £18,842. Congratulations to everyone at Latham & Watkins London! You can still keep donating and sending in match funding until the deadline on the 6 November. Take a look at our leaderboard and how our teams did last week. https://lnkd.in/ejYCHrym

A huge thank you to Gateley for sharing why they took part in the Tour De Law this year. We’re so close to hitting our £150,000 target. Amazing work from all the firms involved! Check out the leaderboard 👇 https://lnkd.in/e2JC46dx

🔬 Finding a new target for secondary breast cancer in the brain. Up to 30% of people whose breast cancer has spread will develop tumours in the brain. Because of their location, these tumours are particularly hard to treat. Recent research by Walk the Walk Worldwide Fellow Damir Varešlija and Professor Leonie Young found that a protein called RET plays a key role in the spread of oestrogen receptor (ER) positive breast cancer to the brain. They found RET helps cancer cells stick to brain tissue, survive, and grow. And that it works with another protein to help these cancer cells spread to the brain. The team also found that targeting RET using specific inhibitor drugs significantly reduced the spread of breast cancer cells in the brains of mice. And they noticed that high levels of RET are linked to worse outcomes in people with ER-positive breast cancer. The team hope that future clinical trials will help to identify if RET inhibitors are an effective treatment for people with secondary breast cancer in the brain. https://lnkd.in/dqcCVK85

“I was diagnosed with breast cancer at age 44. As a man, I struggled to find my place and I felt isolated, especially after having surgery. Men are often overlooked in the breast cancer conversation. That’s why it’s such an honour to represent men who’ve been affected by breast cancer and bring attention to this group.” - Phil “In February 2014, at the age of 25, I was diagnosed with stage 3 primary breast cancer. It was HER2 and oestrogen positive. My treatment included chemotherapy, radiotherapy, a mastectomy and hormonal medication.” - Laura “I was diagnosed with grade 3 primary breast cancer at 23 years old. It was HER2 positive, so I needed to have 6 rounds of chemotherapy. I lost a lot of weight and all of my hair. I also had a nipple-sparing double mastectomy, and permanent breast implants 6 months later. A year later, I had another surgery to remove my nipples to minimise the risk of breast cancer returning.” - Ella FAIRFAX & FAVOR have been supporting us for 9 years now. Each October, they sell a limited-edition range of products to mark Breast Cancer Awareness Month, with 100% of the profits going to Breast Cancer Now. Full donation amounts can be found listed with each product on the Fairfax & Favor website This year, we’re highlighting the stories of our brand ambassadors Phil, Laura and Ella who recently modelled for Fairfax & Favor and showcased their individual styles. Find out more about Phil, Laura and Ella’s story and check out Fairfax & Favor’s limited-edition Breast Cancer Awareness range 👇 https://lnkd.in/egWh_RE4

Most breast cancers don’t come back after treatment. But sometimes they can return, so it’s important you know what signs and symptoms to look out for. This Secondary Breast Cancer Awareness Day, discover the possible signs of secondary (metastatic) breast cancer. And tell your breast care nurse or GP if you have any symptoms that are new, don’t have an obvious cause and don’t go away. https://lnkd.in/eyF92pwq

Secondary (metastatic) breast cancer occurs when breast cancer cells spread from the breast to other parts of the body. Ahead of Secondary Breast Cancer Awareness Day tomorrow, discover more about what secondary breast cancer is. https://lnkd.in/ekZ2wiGm

Thank you to everyone who took part in Tour de Law 2024! It was an amazing 2 days watching our law firms and chambers ride their way to victory and compete for the Tour de Law top spot. So far, we have raised an incredible £113,010! You can still donate to the teams fundraising total and help us get to £150K. These funds will make a huge impact in helping support anyone affected by breast cancer. You can stay up to date on the Tour de Law webpage or you can visit the Tour de Law leader board and donate to the teams who are fundraising 🚲 https://lnkd.in/eJc5aeUz

Do you have questions about family history and genetics in relation to breast cancer? Is this an area you’re interested in learning more about? Join us for our LinkedIn Live where our nurse Cassie will be joined by Andrea Forman, Lead Consultant Genetic Counsellor-Cancer and Clinical Lead - Virtual Family History Service, and Caroline Presho, a BRCA2 mutation carrier and motivational speaker regarding her journey with a high risk of developing BRCA related cancer.

“We want to improve survival for people with triple negative breast cancer. We’re exploring a new combination therapy that could make chemotherapy more effective, and improve outcomes for people with this type of breast cancer.” - Professor Richard Clarkson Researchers think that resistance to chemotherapy comes from a special type of tumour cell, called the breast cancer stem cell. Richard and his team believe that a protein called cFLIP helps these cancer cells resist chemotherapy. And, that it could work in 2 ways – helping breast cancer stem cells stay alive, and helping them hide from the immune system. The team hope that by blocking cFLIP, they can make breast cancer cells sensitive to chemotherapy again. They'll test a drug they’ve made to block cFLIP on breast cancer cells grown in the lab and in mice. They’ll also use it in combination with various chemotherapies to see which one would work best. https://lnkd.in/eVVdmW3F