This week, we're continuing our Medication Spotlight with 𝗔𝗻𝗴𝗶𝗼𝘁𝗲𝗻𝘀𝗶𝗻-𝗖𝗼𝗻𝘃𝗲𝗿𝘁𝗶𝗻𝗴 𝗘𝗻𝘇𝘆𝗺𝗲 𝗜𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀 (𝗔𝗖𝗘 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀)
𝗪𝗵𝗮𝘁 𝗔𝗿𝗲 𝗔𝗖𝗘 𝗜𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀?
ACE inhibitors, or Angiotensin-Converting Enzyme inhibitors, are a class of drugs commonly prescribed to manage high blood pressure (hypertension) and heart conditions. In patients with aortic disease, controlling blood pressure is critical to preventing further damage to the aorta. High blood pressure increases the force exerted on the aorta's walls, significantly raising the risk of rupture. By lowering blood pressure, ACE inhibitors help to stabilize and minimize the strain on the aorta.
𝗛𝗼𝘄 𝗗𝗼 𝗔𝗖𝗘 𝗜𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀 𝗪𝗼𝗿𝗸?
ACE inhibitors work by blocking the enzyme that converts angiotensin I to angiotensin II, a substance that causes blood vessels to narrow. When angiotensin II is reduced, blood vessels relax and widen, allowing blood to flow more easily. This decreases blood pressure, which reduces the amount of force the heart needs to pump blood through the aorta.
Lowering blood pressure with ACE inhibitors is vital for patients with aortic disease because it helps slow down the progression of aneurysms and reduces the risk of dissection. Also, ACE inhibitors improve heart function, which is helpful in patients whose aortic disease is accompanied by heart failure or other cardiovascular issues.
𝗖𝗼𝗺𝗺𝗼𝗻 𝗔𝗖𝗘 𝗜𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀 𝗶𝗻𝗰𝗹𝘂𝗱𝗲:
Lisinopril
Enalapril
Ramipril
𝗠𝗼𝗿𝗲 𝗕𝗲𝗻𝗲𝗳𝗶𝘁𝘀 𝗼𝗳 𝗔𝗖𝗘 𝗜𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀!
Studies suggest that ACE inhibitors can reduce inflammation and improve the structure of blood vessels over time, which may help prevent the development or progression of aneurysms. ACE inhibitors are used to prevent excessive aortic dilation for patients with conditions like bicuspid aortic valve disease.
𝗟𝗼𝗻𝗴-𝗧𝗲𝗿𝗺 𝗨𝘀𝗲
Like beta-blockers (spoken about in our first Medication Spotlight post), ACE inhibitors are often a long-term treatment for patients with aortic disease. Regular monitoring by healthcare providers is essential to ensure that the medication effectively controls blood pressure and prevents complications. Patients on ACE inhibitors may also undergo routine blood tests to check kidney function and electrolyte levels, as these medications can affect both. If you or a loved one has been prescribed ACE inhibitors for aortic disease, it’s crucial to take them as prescribed and work closely with your healthcare team to monitor your condition.
Always consult your doctor to understand the best treatment strategy for your unique situation.
#aortaed #aortichope