We're excited to announce that Takeda and Beacon Biosignals have entered a strategic collaboration to conduct at-home sleep monitoring to support clinical trials in the Takeda orexin franchise and neuroscience portfolio! Takeda will leverage Beacon's neurophysiology platform, including the FDA-cleared Dreem 3S EEG headband, AI-powered analytics, and clinico-EEG database. Quantitative sleep data has been historically difficult to collect and analyze at the speed and scale necessary to support clinical development. This collaboration enables Takeda to collect lab-quality sleep data from a patient's home, longitudinally and at-scale, to characterize sleep dysfunction and enable more personalized treatment options. “Takeda is committed to developing life-transforming therapies for areas of highest unmet need, including narcolepsy and other sleep-wake disorders. In partnering with Beacon, we will now have access to real-time, longitudinal sleep data that better reflects the daily burden of living with these disorders,” said Elena Koundourakis, head of the Orexin Franchise Development and Neuroscience Portfolio Strategy at Takeda. “The Beacon Platform will be used to inform our clinical trial designs including defining quantitative, digital endpoints based on objective measures of sleep patterns, which could support more tailored treatment approaches and improve the diagnostic journey for patients.” We're committed to improving the patient experience and operationalizing at-home sleep endpoints at-scale, and we're thrilled to work with Takeda to pave the way towards novel therapeutic approaches for neurological and psychiatric indications. Full press release: https://lnkd.in/gERHr48j To learn more about Beacon: https://lnkd.in/errYwFaE #takeda #beacon #collaboration #EEG #Dreem #narcolepsy #orexin
Beacon Biosignals
Software Development
Boston, MA 6,497 followers
Our mission is to improve human health by enabling rapid, targeted interventions through advanced brain analytics.
About us
Beacon's AI platform for brain data enables and accelerates new treatments that transform the lives of patients with neurological and psychiatric disease. Through FDA-cleared EEG wearables, novel machine learning algorithms, enormous datasets, and advances in software engineering, we are changing the way patients are treated for disorders of the brain.
- Website
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http://beacon.bio
External link for Beacon Biosignals
- Industry
- Software Development
- Company size
- 11-50 employees
- Headquarters
- Boston, MA
- Type
- Privately Held
- Founded
- 2019
Locations
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Primary
Boston, MA 02114, US
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New York, New York 10007, US
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Palo Alto, CA 94301, US
Employees at Beacon Biosignals
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Naveen Rao
VP of AI at Databricks
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Ilan Goodman
VP Platform at Beacon
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David Little
Neuroscientist at Beacon Biosignals
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Stacey Tindell
Highly skilled and experienced Creative Art Director with a strong background in creating visually compelling and impactful advertising. Specializing…
Updates
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Congrats to our partners at Cerevance on this important milestone with Merck as they continue advancing the treatments of neurodegenerative, psychiatric and central nervous system disorders!
We've achieved our second milestone in our research collaboration with Merck and are excited by the advancements we’ve made in identifying potential novel therapeutic targets for patients with Alzheimer’s disease. A huge thank you to our dedicated team and partners at Merck for their hard work and commitment to excellence. Read the press release here: https://lnkd.in/eFFxkMgH
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Standing on the shoulders of giants! A huge congratulations to Dr. John Hopfield and Dr. Geoffrey Hinton for receiving the Nobel Prize in Physics today for their contributions in machine learning! Their foundational work in artificial neural networks unlocked a world of AI applications that has reshaped nearly every field of science and medicine. A few of our team here at Beacon studied with John, and we're proud to play a part in carrying on his and Geoff's legacy by implementing ML models to better characterize neurophysiological signals, diagnose neuropsychiatric and neurodegenerative disease, and develop new treatments to usher in an era of precision medicine for the brain. #nobelprize #physics #machinelearning #hopfieldnetwork #boltzmannmachine
The Nobel Prize in Physics 2024
nobelprize.org
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Beacon Biosignals reposted this
I was glad to join the World Medical Innovation Forum in Boston recently with many respected leaders representing health care, government, academia and the investment community. For me, the forum reinforced that while we face some challenges, the importance of sustained innovation in the U.S. and the strength of the local health care ecosystem in Massachusetts shouldn’t be underestimated. It was also a pleasure to join Bank of America’s Jason Gerberry and Mass General Brigham’s Allan Goldstein on stage to reflect on our transformation at Takeda and the many exciting things we’re looking forward to at the company. I’m confident we have the right strategy, teams and focus to deliver for patients today and in the future. We’ve made great progress in focusing and advancing our pipeline over the past 10 years, and today we have several assets in late-stage development with great potential. We also discussed how our global culture helps keep us competitive. We’re a Japanese company with a Global Hub in Massachusetts and a presence in more than 80 countries and regions. Our values help create an environment that brings people together and encourages everyone to share unique perspectives. From a personal point of view, I greatly value having nine nationalities and 53% female representation on our executive team. Interested in hearing more on the intersection of innovation and investment? Watch the conference recordings here: https://lnkd.in/eSP2TWJ7 #WMIF2024
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Join us at HLTH USA where Beacon’s CBO David Matthews, PhD will be on stage with our Takeda partners discussing Digital Innovation in Sleep! #sleep #digitalhealth #HLTH
💤 Innovating Sleep Solutions: Pharma & Tech Collaboration 💡 Join us at HLTH USA, Las Vegas for an exclusive HLTH Community Insider: "Pharma Partnerships to Drive Digital Innovation in Sleep" In partnership with Takeda Pharmaceutical, we're exploring: 🤝 Strategic alliances between pharma and startups 🚀 Accelerating effective sleep solutions 💪 Improving patient outcomes Featured speakers: 🎤 Sara Sarkey, VP Neuroscience and Vaccines, US Medical, Takeda Canada Inc. Pharmaceutical 🎤 David Matthews, Chief Business Officer, Beacon Biosignals 🎤 Jen Horonjeff, CEO, Savvy Cooperative 🎤 Chandana Fitzgerald, President, HLTH Community Register your intrest to be part of this transformative event! 🔗 https://lnkd.in/dhdptfiK #SleepInnovation #HLTHUSA #PharmaPartnerships #HealthTech
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Beacon Biosignals reposted this
Alongside Project Sleep, in recognition of #WorldNarcolepsyDay, we stand strong with patients and communities impacted by #narcolepsy and related sleep-wake conditions. Our vision is to continue enhancing the lives of patients, paving the way for better health and a brighter future. Meet Kelsey, a person living with narcolepsy type 1 (NT1) who describes her own experience and journey with this rare, often misunderstood disorder. Watch the full video: https://lnkd.in/efdPH3rS Kelsey is a paid speaker for Takeda. Individual symptoms and experiences may vary. Please consult a healthcare provider with questions about any health concerns you may be experiencing. Takeda does not currently have any approved treatments for narcolepsy.
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Congratulations to Beacon partner Longboard Pharmaceuticals on their success in receiving the FDA's Rare Pediatric Disease designation and Orphan Drug designation for its investigational drug bexicaserin for the treatment of Dravet syndrome. We're proud to work with bold innovators serving rare disease populations with significant unmet medical needs, and especially excited for the potential impact that bexicaserin will have for Dravet Syndrome patients! Congrats Randall Kaye and the entire Longboard team!
Today, we announced Rare Pediatric Disease and Orphan Drug designations for bexicaserin in Dravet syndrome - another terrific regulatory milestone! Additional details available here https://bit.ly/3XzAKna
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📣 Beacon is proud to announce the launch of the HEADFIRST basket study (“Home EEG Application and Dreem Feasibility In Research Study”), with our first cohorts enrolled via partnership with the Lennox-Gastaut Syndrome (LGS) Foundation! HEADFIRST is a basket study that aims to assess the Dreem 3S headband's usability in tracking sleep and brain activity in both pediatric patients with neurodevelopmental disorders and in neurotypical controls, enrolling up to 300 participants across multiple disorders. The first phase of the study, in partnership with the Lennox-Gastaut Syndrome (LGS) Foundation, focuses on usability, reliability, and clinical utility of using Dreem for a pediatric cohort with LGS. Sleep disturbances are a known complication in pediatric neurodevelopmental disorders, significantly affecting patients and their caregivers. In this study, Beacon will assess the extent to which the Dreem3S overcomes the challenges posed by traditional wired EEG systems, which can be intrusive and disruptive while limiting longitudinal data collection. Additionally, the study will harness Beacon’s machine learning analytics platform to measure quantitative sleep and EEG endpoints, potentially paving the way for novel therapeutic approaches and improved patient outcome measures. The LGS Foundation will raise awareness for the study’s first cohorts, ensuring that families affected by LGS have the opportunity to participate. Furthermore, we're excited to collaborate with two biopharma partners who have joined the study at launch to share data, gain insights, and explore candidate sleep EEG biomarkers. With HEADFIRST, we're uniting to make a meaningful difference in the quality of life of patients and families impacted by LGS and other neurodevelopmental disorders. We encourage other biopharma leaders to reach out to learn more about adding specific cohorts to HEADFIRST and exploring the importance of sleep physiology for their development programs. The Dreem 3S is an FDA 510(k)-cleared medical device cleared to study sleep in adults, and is being evaluated for research purposes in pediatric populations. To learn more about how you can utilize Dreem in your trials, reach out to us: https://beacon.bio/contact See today's press release here: https://shorturl.at/DwCY0 #HEADFIRST #Dreem #EEG #LennoxGastaut #ClinicalTrials #Sleep #biomarkers
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Come say hello at ISCTM 2024 [https://lnkd.in/eGUR9fH] in San Diego, CA this Thursday September 12, where our Chief Business Officer David Matthews, PhD will be presenting on our computational approaches to leverage EEG and PSG for endpoints in developmental disorders! In this presentation, we share recent computational approaches used to discover biomarkers in neurodevelopmental and sleep disorders from EEG and PSG data, including seizure burden, periodic discharges, interictal epileptiform discharges, and others, across a diverse set of developmental and epileptic encephalopathies (DEEs). Beacon is actively working with biopharma partners to leverage our FDA 510(k)-cleared algorithms for EEG endpoints in clinical trials for epilepsy, sleep disorders, psychiatric and neurodegenerative disorders, and more. To meet with us at the ISCTM conference or to learn more: beacon.bio/contact #ISCTM2024 #Dreem #Conference #SanDiego
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Beacon extends its congratulations to Gain Therapeutics, for its positive Phase 1 data last week of GT-02287 in healthy volunteers! The mechanism of GT-02287 aims to restore the function of a lysosomal protein enzyme called glucocerebrosidase, which selectively affects disorders that have mutations in the GBA1 gene, the most common genetic abnormality associated with Parkinson’s. The Phase 1 trial demonstrated that the drug was “safe and generally well tolerated up to and including the highest planned dose levels across all age groups.” The allosteric modulator drug class has struggled to yield efficacious drugs for PD in recent history, and this latest Phase 1 result shows promise for Gain Therapeutics and for PD patients with and without the GBA1 mutation. At Beacon, we're working with our biopharma partners to measure treatment-responsive sleep biomarkers in neurodegenerative disorders including Parkinson's disease, aiming to identify predictive biomarkers and improve patient outcomes. Read more: https://lnkd.in/gwa2bxhU To learn more about how we can work together to make an impact in Parkinson's disease, contact us below: https://beacon.bio/contact #parkinsons #PD #GBA1 #sleep #EEG #clinicaltrials
Gain hopes to prove Parkinson's drug's potential next year after phase 1 win for allosteric modulator
fiercebiotech.com