Cleveland Clinic Lerner Research Institute

The future of research is here at Cleveland Clinic. Lerner Research Institute scientists are making the impossible possible through innovation, collaboration and a commitment to improving the health of generations to come. Watch on YouTube: https://bit.ly/3BLGot0

Dr. Keith McCrae's recent study on hereditary hemorrhagic telangiectasia (HHT) treatment was featured on the NIH Director's blog! His NIH-supported clinical trial of pomalidomide shows success in treating HHT. Dr. McCrae hopes to continue studying HHT, clarifying the mechanisms behind the disease. Read the blog here: https://lnkd.in/gZz3MATM More on Dr. McCrae's study: https://lnkd.in/gPfVXbJ3

Cleveland Clinic researchers have discovered a new genus and species of bacterium, Tomasiella immunophila (T. immunophila) 🦠 Thaddeus Stappenbeck, MD, PhD, and Qiuhe Lu, PhD, (pictured) led the study identifying the bacterium. Their work is the first step to potential new treatments for a variety of inflammatory and infectious diseases including IBD, Crohn’s and ulcerative colitis. Read more: https://lnkd.in/gfuiEE2T #ClevelandClinic #IBD #Chrohns #inflammation #infectiousdisease

Dr. Jos Melenhorst and his team have published findings identifying factors that increase CAR T-cell therapy’s cure rate for acute lymphoblastic leukemia (ALL) in children and young adults. Their findings have already set the groundwork for future research to better understand these factors. Read more: https://lnkd.in/gtp4TjFP #ClevelandClinic #Leukemia #Research #Cancer

Cleveland Clinic’s Dr. Keith McCrae saw a patient with a rare blood disorder that had no available treatment. This sparked his research to find a solution! Dr. McCrae recently led a clinical trial supported by The National Institutes of Health, showing that the immunomodulatory drug pomalidomide is both safe and effective for treating hereditary hemorrhagic telangiectasia (HHT). While this is great progress, there’s still much to learn about the disease. Dr. McCrae plans to continue his work on HHT: https://lnkd.in/gPfVXbJ3 #ClevelandClinic #BloodDisorder #Hematology

Cleveland Clinic researchers in the Stenosis Therapy and Antifibrotic Research (STAR) Consortium have developed a new method using MRI and CT imaging to measure and track intestinal strictures in Crohn’s disease. The new approach opens the door for the development of antifibrotic therapies, providing clear metrics for clinical trials and ultimately helping to enhance patient care. Read more here: https://lnkd.in/g2btGwPH #CrohnsDisease #ClevelandClinic

Women We Admire has recognized Dr. Lara Jehi as one of the Top 50 Women Leaders of Cleveland for 2024! 🎉 As the inaugural Chief Research and Information Officer and Director of the Center for Computational Life Sciences at Cleveland Clinic, Dr. Jehi has made an incredible impact. With over 200 peer-reviewed publications, her data-driven algorithms for clinical care decision-making are being used, studied and expanded worldwide. Join us in celebrating Dr. Jehi and the honorees who are committed advancing their organizations and the Cleveland community! 👏 See the full list here: https://lnkd.in/grf6PQCR More on Dr. Jehi's work: https://lnkd.in/gmDV8awW #WomenWeAdmire #Cleveland #ClevelandClinic #WomeninResearch #WomeninScience #WomeninSTEM

Congratulations to the Quantum System One Unveiling Team 🎉 Last week, Cleveland Clinic's Quantum System One Unveiling team was recognized with a Team Innovation Award at the 2024 Caregiver Awards Ceremony. Congratulations to this team of more than 50+ caregivers from Lerner Research Institute, Lerner Research Computing, Legal, ITD, Construction, Marketing & Communications, Philanthropy, Government Relations, Security and Protective Services. The award recognizes the effort that culminated in the official unveiling of Cleveland Clinic's Quantum System One last year. Total attendance for the opening event exceeded 250 guests from more than 10 countries and representing over 20 different companies, and included Congresswoman Shontel Brown (OH-11), Lt. Governor of Ohio Jon Husted and Mayor of Cleveland Justin M. Bibb. The event garnered unprecedented media attention, with 12.2M total impressions in 355 individual media placements. Congratulations to the team for this well-deserved recognition! #CaregiverAwards #ClevelandClinic #HealthcareLeadership #Quantum

Happy National Postdoc Appreciation Week 🎉 Thank you to all of our postdoctoral fellows for your dedication and significant contributions to research at Cleveland Clinic! Check out virtual events hosted nationally by the National Postdoctoral Association: https://lnkd.in/eXXpthiy #NPAW2024 #PostdocAppreciation

Dr. Hod Dana partnered with Drs. Ken Baker and Andre Machado take a deeper look inside the "black box" of the brain 🧠 Their research aims to decode the complexities of neural activity, with the ultimate goal of enhancing stroke treatment strategies. Read more about their work: https://lnkd.in/gXvUTa2n #BrainResearch #Neuroscience #StrokeRecovery #StrokeTreatment #ClevelandClinic