Eurofins Discovery

Did you know? SRC homology 2 (SH2) domains play a central role in mediating protein-protein interactions by recognizing and binding phosphotyrosine residues on target proteins involved in the regulation and organization of cell signaling and macromolecular complex assembly in the cell. In addition to targeting SH2 binding domains of STAT proteins and kinases, we’ve expanded our SH2scan offering to include E3 ligases, adaptor proteins, phosphatases, GTPase-activating proteins, and phospholipases for a comprehensive SH2MAX panel that brings this “undruggable” target class within therapeutic reach. Get more information: https://lnkd.in/gR6JtWuQ Curious about these new services? Speak with an expert 📣 https://lnkd.in/g_Vv3c8H

There is still time to register for tomorrow’s eagerly anticipated webinar: CRISPR MDCKII Cell Lines Development for Bioavailability and DDI Assessments. Register for FREE at https://lnkd.in/gkD6PtJ5 #DrugDiscovery

Our team is ready to meet you at the EFMC-ISMC in Rome, Italy! Between now and September 5th, stop by booth #40 to speak with Vanessa Porkolab, Olivier Mirguet, Sahar Davatgarbenam, E. Marco Gargano, PhD, Vincent CORVEST and Jose Manuel Villalgordo Soto about our latest posters, biology & chemistry methods, and our protein production to help drive your drug discovery projects. Eurofins Discovery supports you in accelerating your drug discovery programs by helping identify, characterize and de-risk your next generation of hits.   For more details about the event: https://lnkd.in/eGpJu4Mh #EFMC #Eurofins #DrugDiscovery

🚀 Accelerate Your Path to Discovery with Eurofins Discovery Chemistry Want to streamline your journey to the next breakthrough Active Pharmaceutical Ingredient (API)? Need to refine your synthesis route or secure your API supply? Eurofins Discovery is here to help. Our cutting-edge EU-located Chemistry capabilities empower you to drive SAR exploration, optimize early process development, and hit your discovery milestones faster. Our expert teams harness advanced technologies like high-throughput experimentation, automated parallel medicinal chemistry, and scale-up capabilities to reduce cycle times and accelerate progress. Partner with us for Fee for Services (FFS) or Full-Time Equivalent (FTE)-based collaborations that offer competitive pricing, robust IP protection, and top-tier project management, all within our European labs. 👉 Download our flyer to learn more about our Discovery Process Chemistry team: https://lnkd.in/gXGq8S2B 👉 Reach out today to see how we can propel your drug discovery journey forward: https://lnkd.in/gJYZvd79   #DrugDiscovery #Chemistry #Innovation #Eurofins

Looking for an ADME partner of choice? Eurofins Discovery is with you every step of your Drug Discovery journey. We offer a wide range of ADME assays, covering all your needs and enabling your compounds to evolve with ideal PK properties. Eurofins ADME Services includes: ·       Testing site and technical support in Europe ·       Quality - 25+ years providing in vitro ADME services ·       Flexibility - modifications of current SOP available ·       Speed - turnaround times in less than 5 days are available Access our flyer presenting our early ADME capabilities! Reach out now to E. Marco Gargano, PhD, EmanueleMarco.Gargano@discovery.eurofinseu.com, or meet him at booth #40 next week at #EFMC-ISMC in Rome! Want to learn more? Don’t miss the opportunity to listen to our ADME team leader, Shantanu Roychowdhury during his upcoming webinar, showcasing “CRISPR™ MDCKII cell lines development for bioavailability and DDI assessments”. register here: https://lnkd.in/gkD6PtJ5

Don't miss out - only one week left to register for our September 4 webinar! Discover the latest offerings for drug-drug interaction assessments using CRISPR KO/KI MDCKII cell lines. Register Now: https://lnkd.in/gkD6PtJ5 #CRISPR #druginteration #celllines #proteomics

Are you looking forward to connecting with experts to discuss the latest breakthroughs in drug discovery? Interested in cutting-edge Chemistry Services? Eager to learn more about Hit Finding strategies? Here is a sneak peek of “Rational Design and Profiling of PIM Kinases Degraders”, one of the posters we will be presenting at the EFMC-ISMC in Rome, Italy! Meet with a key author and presenter, Olivier Mirguet and learn more about our developments in this exciting field. In this poster, using our PIM3 program, we illustrate how it is possible to expedite the discovery of novel degraders. Our experts designed a library of PIM kinase bifunctional degraders that were synthesized using Eurofins Discovery’s Automated Robotics Lab. We show the full characterization of the degraders by employing PIMs activity-based assays and ternary complex formation using biophysics. Not one, not two, not three, but four posters will be presented at the EFMC-ISMC! We will be covering topics from DiscoveryAI to Biophysics, as well as recent developments regarding Helicases. Stop by Booth 40 to speak with our team and learn more about these projects! For more about the event, visit: https://lnkd.in/g2t9zRUB Watch this space, as we will share the full poster following the EFMC-ISMC 2024. 😊 #EFMC #DrugDiscovery

Don’t miss the August edition of BioPharma Services News, featuring the Eurofins DiscoveryAI™ end-to-end computational services for drug discovery. Luis Miguel Gonçalves, Jessica Marty, Sarah Biehn, and Carleton Sage walk you through the DiscoveryAI offering that combines the power of AI with high-quality Eurofins Discovery proprietary data that enable clients to succeed early, improve decision-making, and explore chemical space beyond human capacity. ☑  SAFIRE advanced AI tools: A collection of AI models trained with high-quality, curated proprietary datasets that predict ADMET properties. ☑  EMERALD data as a service: Gain access to high-quality proprietary datasets for ADMET and dosage. ☑  Comprehensive computational chemistry services: Eurofins DiscoveryAI’s seasoned drug hunters leverage advanced in silico techniques for faster identification and optimization of lead compounds. ☑  Advanced visualization tools: Obtain interpretations of assay results and recommendations for follow-up studies. Experience the future of drug discovery with DiscoveryAI solutions: https://lnkd.in/gn5pXDud #EurofinsDiscovery #drugdiscovery #ai

Don't miss Eurofins DiscoverX's newest blog & catch up on recent advances in non-opioid pain research as the prevalence of debilitating pain disorders & opioid misuse call for innovation in the development of non-addictive molecules. The blog summarizes a recent ion channel webinar which highlights the development & characterization of a novel Nav1.8 inhibitor and introduces ready-to-assay frozen cells for cardiac safety targets to support ion channel drug discovery programs. Read the recap: https://lnkd.in/gPrtr2bY #drugdiscovery #opioid #ionchannel #cardiacsafety

Countdown to #ICNS2024! Just days away! 🚀 Are you tackling complex neurological disorders? Join us at ICNS 2024 in China! 👨🏫 Meet Our Expert: Chun-Yao Lee, Managing Director at Eurofins Panlabs Discovery Services Taiwan. He will be available to provide expert consultations and share insights. Why Visit Us? ⭐ Transform your drug discovery journey ⭐ Expedite your project timelines ⭐ Enhance your research outcomes Don’t forget to drop by our Booth B4 to connect with us and explore innovative solutions. For event details, visit: https://lnkd.in/gg-ae4cn #CNS #Neuron #China #EurofinsDiscovery #DrugDiscovery