Multiply Labs

We’re thrilled to announce our collaboration with Legend Biotech, focused on automating cell therapy manufacturing! Excited to work with some of the best scientists in the field.  Through this collaboration, Legend Biotech will evaluate our robotic technologies, and secure priority access to those automated systems. The Multiply Labs approach to automating cell therapy manufacturing - as seen in this video - is rooted in the promising results of our  peer-reviewed study in Cytotherapy, which highlighted statistical equivalence between manual and automated cell expansion processes. This collaboration will help showcase the potential of our flexible automation solutions, bringing us closer to our vision of reducing labor costs and increasing manufacturing throughput. Learn more about the news here: https://bit.ly/3TG8JsG   #CellTherapy #Robotics #Innovation #Pharma #BioTech

Did you catch Fred (Federico) Parietti's panel at Italian Tech Week? 🙌 It was inspiring to see the conversation around personalized cell therapy manufacturing evolve alongside industry leaders like Ileana Pirozzi, Fred Manby, and Raviv Pryluk. The future of pharma is about more than just scaling production—it’s about scaling personalized treatments that address individual patient needs. As Fred noted during the “Bioindustrial Revolution: Robots, Quantum, and AI” panel, there are no shortcuts when it comes to personalized cell therapy treatments. Our robotic system for the automated manufacturing of cell therapies is designed to meet this challenge head-on, offering unprecedented efficiency and throughput. Building trust is key in pharma. At Multiply Labs, we’re committed to transparency by publishing peer-reviewed data that shows our robots are not just equivalent to manual methods, but also reduce contamination risks. To continue moving our research forward, we’re able to use our robotic system to collect and analyze vast amounts of manufacturing data, far beyond what’s possible with human hands alone. Thank you to everyone who joined us at #ITW2024. Here’s to the future of personalized cell therapy treatments! 💊🤖 #Pharma #Robotics #AI #Innovation #Automation #CellTherapy

Let’s talk about solving critical challenges in cell therapy manufacturing! Our Head of Robotics Software, Nadia K., and Senior Robotics Software Engineer, Varun Bhatia, will be presenting at the upcoming LRIG Bay Area Chapter Event: Integrating Informatics, Automation, and Machine Learning for Smarter Labs tomorrow! They’ll be presenting on “Accelerating Cell Therapy Access: Robotic Solutions for Scalable Manufacturing,” addressing crucial challenges in cell therapy manufacturing. Currently, hundreds of thousands of patients need these life-saving therapies, but reliance on a highly skilled and limited labor pool brings significant barriers to treatment access and affordability. During their session they’ll walk through: 🦾The power of automation to increase throughput and accelerate production timelines — scaling from just 1 or 2 products per incubator with manual processes to 18 products in parallel with automated processes. 🦾Robotics’ role in minimizing contamination risk and reducing human error, ensuring safer and more consistent results. 🦾How AI imitation learning is helping us mimic lab technicians' manual motions, further enhancing efficiency. 🦾Overcoming regulatory challenges by automating market-leading GMP instruments already deployed in cell therapy manufacturing. 🦾Flexible automation solutions that use less space and ensure manufacturers are future-proof. 🦾How these technologies can radically reduce cell therapy manufacturing costs by up to 70% per product. We’re excited to connect with fellow innovators and discuss the cutting-edge solutions shaping the future of biotech and lab automation. 🤖🧪 #CellTherapy #Robotics #Automation #LRIGBayArea #LRIG #BioTech #AI

⭐We're Hiring!⭐ Last week, we had an amazing time connecting with brilliant minds at the MIT career fair. Up next, we’re headed to: 📍University of California, Berkeley on Wednesday, October 2nd 📍Massachusetts Institute of Technology on Friday, October 4th 📍Stanford University on Thursday, October 10th We’re seeking talent for the following roles to join our team in San Francisco! ➡️Software Engineers ➡️Robotics Software Engineers ➡️Robotics Engineers ➡️Mechanical Engineers ➡️Process Development Scientists By working with us, you'll play a crucial role in improving patient access to live-saving therapies through automated cell therapy manufacturing. This is your chance to get in on the ground floor of a startup that’s revolutionizing pharma robotics to make a real difference in patients' lives. Let’s build the future of cell therapy manufacturing together! 💡 Will we see you at an upcoming career fair? Let us know in the comments! #Hiring #Recruitment #Engineering #Biotech #Robotics #MIT #Stanford #UCBerkeley

In a recent article for Drug Discovery News, Stephanie DeMarco, PhD highlighted a few of the top of reasons cell therapy manufacturing is a perfect fit for automation: 🧪Cell therapies hold enormous potential for treating diverse conditions, from cancer to autoimmune diseases. However, manufacturing enough of them to meet patient needs at scale is difficult with traditional, manual manufacturing processes. 🥼The need for highly trained staff to create these therapies drives up the manufacturing cost, which in turn increases the price of the therapies, limiting patient access.  🦠Many of the steps needed to create cell therapies require researchers to manually transfer cells from one vial to another, which can introduce batch variability as well as an increased risk of contamination. These issues can all be addressed through automation. Read on to learn more with great insights from Jonathan H. Esensten, M.D., Ph.D., Matthew Hewitt, Fred (Federico) Parietti, and Renske ten Ham: https://lnkd.in/dNg_WpBd #Innovation #CellTherapy #Robotics #Pharma #Automation

CAR T cell therapy is one of many cell therapies being used to treat diseases today. CAR T cell stands for chimeric antigen receptor T cell. This therapy involves modifying the patient’s own immune cells (T-cells) to express a receptor on their surface that recognizes structures (antigens) on the surface of malignant cells. Once the receptor binds to a tumor antigen, the T-cell is stimulated to attack the malignant cells. There are many intricate details involved in manufacturing CAR T cell therapies, but at a high level there are 4 main steps…scroll through to learn more! Sources: The Leukemia & Lymphoma Society: https://lnkd.in/gGnNh_UN American Society of Gene & Cell Therapy: https://lnkd.in/gegpcaF

Congratulations to Rutgers Cancer Institute and RWJBarnabas Health on treating their 200th CAR T-Cell Therapy patient! 🎉 Because CAR T-Cell therapy is a highly personalized treatment, it is only available at a limited number of cancer centers with specialized expertise, such as Rutgers Cancer Institute. It is amazing to see the success of cell therapy programs around the world as we continue on our mission to build a future with more accessible cell therapies through automated manufacturing processes. Read more 👉 https://lnkd.in/gE-DhuWd #CellTherapy #Automation #Pharma

Meet our co-founder and Chief Scientific Officer, Alice Melocchi – the woman behind Multiply Labs’ pharmaceutical research 🧪 With the goal of using robotics to increase access to cell therapies for patients in need, she and co-founder Fred (Federico) Parietti made the ideas that were first discussed in a Massachusetts Institute of Technology (MIT) lab a reality by founding Multiply Labs. This is Alice’s #FounderStory💡 “Fred and I met at MIT. I was a PhD student from the University of Milan, working in the Department of Chemical Engineering, and more specifically within the Novartis MIT Center for Continuous Manufacturing, and he was doing his PhD in Mechanical Engineering, focusing on robotics. We started discussing possible ways to accelerate the development of drug products while allowing relevant personalization.” Recognizing that gene and cell therapies have achieved impressive results in treating diseases previously thought to be “untreatable,” Alice and Fred realized their different sets of skills could be combined to manufacture these life-saving treatments with greater efficiency ⚗️🦾 “Based on the topic of my PhD research, I was interested in broadening my knowledge of technologies belonging to different fields and I was curious about Fred’s work because he was able to build and modify prototypes swiftly, which is unusual in pharma. It was during one of our many discussions like this that the initial idea behind Multiply Labs was born: developing robotic technologies to enable pharma companies to manufacture advanced personalized medicines efficiently and on a vast scale.” Flash forward to today, Alice now leads Multiply Labs' pharmaceutical research effort, developing and implementing procedures to test our robotic systems and to gain proof-of-concept data. This approach helps us figure out possible improvements for our systems. Alice then communicates the results she and the team collect to the scientific community through oral presentations or one of her many publications in peer-reviewed journals. Without Alice, there would be no Multiply Labs and we are grateful to have her brilliance and dedication on our side! If you’re interested in reading any of Alice’s peer-reviewed studies, you can check out her Google Scholar page👉 https://lnkd.in/guPEFjai #pharma #robotics #celltherapy #womenleadership #leadership #womeninSTEM #MIT

💡Did you know that up to 50% of cell therapy manufacturing costs stem from labor-intensive manual processes and a shortage of skilled workers? This is why automation is a no-brainer in this space. Estimates based on industry data show that our robotic system can reduce the cost of typical GMP-level cell therapy manufacturing processes by approximately 70%, on a per-product basis. The lower we can get manufacturing costs, the more accessible cell therapies will be for the hundreds of thousands of patients in need. #CellTherapy #Robotics #Automation #BioTech #PharmaManufacturing

We are feeling like #1 today! It's hard not to smile when we're making progress on our automated system for manufacturing life-saving therapies to increase access for patients in need! #CellTherapy #robotics #automation