👏 Congratulations to NEALS Science Advisory Board Member, Rita Sattler, PhD, MSc, on receiving the Target ALS Basic Biology Consortia Grant! ⬇ Learn more about the grant and Dr. Rita Sattler's work in #ALS research! ⬇
Congratulations to Barrow professor Rita Sattler, PhD, MSc, and her collaborators on receiving a competitive Target ALS Basic Biology Consortia Grant for a project aimed at understanding how TDP-43 dysfunction in glia contributes to #amyotrophiclateralsclerosis (ALS). In 97% of ALS cases, the TDP-43 protein moves from its normal place in the nucleus of cells to the cytoplasm, where it aggregates and affects cell function. Typically, this pathology is studied in neurons. By understanding how TDP-43 dysfunction in the non-neuronal support cells in the #brain contributes to ALS, the consortium hopes to find new ways to treat the disease that can be applied to the 97% of #ALS cases where TDP-43 is affected. Dr. Sattler's collaborators include Dr. Yuna Ayala of Saint Louis University, Dr. Christopher Donnelly of the University of Pittsburgh, Dr. Patrick Pirrotte of TGen - Part of City of Hope, and Dr. Kendall Van Keuren-Jensen of the National Institute on Aging (NIA). Their consortia was one of six that received funding out of applications submitted by 106 scientists from 76 institutions in 13 countries. Learn more about this grant: https://bar.rw/3WrXNzP