ScienCell Research Laboratories

Did you know about ScienCell's distributor list? If you're outside of the US or Canada attempting to purchase our products, you'll need to head to your closest distributor's website to order. Luckily, we have a list of all our distributors and their contact info available on our website (www.sciencellonline.com)! We use distributors for international shipping due to each country having its own customs and regulations laws, especially when it comes to human biologics. Working with distributors streamlines the process so you can get the products your research needs quickly and easily.

The epidermal layer of the skin provides an essential function as a protective barrier against insults from the external environment. The predominant cell type in the epidermis is keratinocytes and they are located in the stratified squamous epithelia. Keratinocytes are named after keratin, which is the most abundant protein in this cell. Human Epidermal Keratinocytes (HEK, Cat. #2100) are characterized by immunofluorescence with antibodies specific to cytokeratin-18 and/or cytokeratin-19. HEK are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HEK are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell. It is recommended to use Keratinocyte Medium (KM, Cat. #2101) for culturing HEK in vitro. Head over to our website sciencellonline.com for more details!

ScienCell's Keratinocyte Medium (KM, Cat. #2101), when used with Keratinocyte Growth Supplement (KGS, Cat #2152), is a complete medium designed for optimal growth of normal keratinocytes in vitro. It is a sterile, liquid medium which contains essential and non-essential amino acids, vitamins, organic and inorganic compounds, hormones, growth factors and trace minerals. The medium is formulated (quantitatively and qualitatively) to provide an optimally balanced nutritional environment that selectively supports the growth of normal keratinocytes in vitro. More information is available on our website sciencellonline.com

As the year winds down, we’re excited to offer you a special discount to THANK YOU for trusting us this past year! Until the last day of 2024, enjoy 10% off on all of our products*! Whether you’re stocking up on essentials or exploring new resources, this is the perfect opportunity to save on our high-quality products you rely on. Shop now and we look forward to supporting your research in the coming year! Let's enjoy joyful holidays and happy savings! *Certain exclusions apply, see our promotions page for more details. Offer valid from 11/1/24 - 12/31/24 for orders up to $8,000 before tax and shipping. Limit of three (3) cell vials per order. Must use code TY10 in notes section of POs or online orders. Promo code will not automatically apply to online orders.

Autism spectrum disorder is a developmental disability that can result in social, communication, behavioral, and learning challenges. The disease is early-appearing, with symptoms often presenting early in childhood, and evidence suggests there is a strong hereditary component. ScienCell’s GeneQuery™ Human Autism Spectrum Disorder qPCR Array Kit (GQH-ASD, Cat. #GK077) profiles 88 key genes associated with autism spectrum disorder. GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. See full details on our website sciencellonline.com #AutismResearch

Protein A, similar to Protein G, is an immunoglobulin-binding protein expressed in group C and G Streptococcal bacteria but with different specificities. Protein A may be conjugated with various reporter molecules including fluorescent dyes (FITC), enzyme markers (peroxidase, α-galactosidase, alkaline phosphatase), biotin, and colloidal gold without affecting the antibody binding site on the molecule. Additionally, Protein A may be immobilized on a solid support such as agarose or acrylic beads for the purification of either polyclonal or monoclonal immunoglobulins. It is also routinely used for immunoprecipitation assays. Protein A is a cell wall component produced by several strains of Staphylococcus aureus that consists of a single polypeptide chain and contains little or no carbohydrate. Explore our website sciencellonline.com for additional information!

Neurons are responsible for processing and transmitting information throughout the body via electric potentials. They are a core component of the central nervous system and specialized neurons are key elements of the sensory and motor units. ScienCell's GeneQuery™ Human Neuronal Cell Biology qPCR Array (GQH-NEU, Cat. #GK078) profiles 88 key genes involved in normal neuron function. GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. Note: all gene names follow their official symbols by the Human Genome Organization Gene Nomenclature Committee (HGNC). Explore our website sciencellonline.com for additional information!

Astrocytes are the major cell type in the mammalian brain. They provide a variety of supportive functions to their partner neurons in the central nervous system (CNS), such as neuronal guidance during development, nutritional and metabolic support throughout life. Numerous studies have demonstrated that astrocytes are among the most functionally diverse group of cells in the CNS. Much of what we have learned about astrocytes is from in vitro studies and astrocyte culture is a useful tool for exploring the diverse properties of this cell type. Mouse Astrocytes (Cat. #M1800-57) from ScienCell Research Laboratories are isolated from C57BL/6 mouse brain. MA are cryopreserved at P0 and delivered frozen. MA are negative for mycoplasma, bacteria, yeast, and fungi. MA are guaranteed to further expand for 5 population doublings under the conditions provided by ScienCell Research Laboratories. It is recommended to use Astrocyte Medium-animal (AM-a, Cat. #1831) for culturing MA in vitro. View our website sciencellonline.com for more information! #research #BioTechUSA #astrocytes #animalcell #california

Astrocytes are the most abundant cells in the central nervous system (CNS). Astrocytes provide a variety of biological functions, such as supporting endothelial cells involved in blood-brain barrier formation, providing nutrients to neurons, maintaining extracellular ion balance, and promoting repair in the CNS. Astrocyte conditioned medium (ACM) has been widely used to support the growth of neurons and endothelial cells in culture. ACM has also been shown to protect neurons from corticosterone-induced damage. Mouse ACM-57 (Cat.#M1811-57) is a liquid medium prepared from primary C57BL/6 mouse astrocyte cultures by using astrocyte medium (Cat #1801) conditioned for 48 hours. Check our website sciencellonline.com for more details!

Mitochondrial DNA (mtDNA) is a circular DNA found inside the mitochondria, and it plays a key role in the cells’ energy production. Damage to mtDNA can disrupt cellular energy processes, leading to decreased cell growth and apoptosis. mtDNA damage serves as a meaningful biomarker for assessing the genotoxicity of drugs and environmental toxins. ScienCell's Human Mitochondrial DNA Damage Quantification qPCR Assay Kit (HMDQ, Cat. #8978) operates on the principle that various DNA lesions can impede DNA polymerase progression. Consequently, DNA with fewer lesions amplifies more readily than damaged DNA under identical conditions. Damage levels can be quantified in terms of the lesions per kilobase pair using a Poisson distribution of lesions or the percentage of intact mtDNA of the target sample to the control sample. Additionally, our assay allows for tracking DNA repair kinetics by measuring the restoration of target DNA amplification over time following the removal of the DNA-damaging agent. For more information, head over to our website sciencellonline.com #research #qpcrassay #BioTechUSA #OctoberDeals