Transplant International

Can C1q have a key role in Acute Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation? An interesting research from a Japanese group. Read more here: https://lnkd.in/dHpSrTiC

Do patients with intellectual disability have different outcomes after solid organ transplantation? A systematic review of the literature answers this question. Read more here: https://lnkd.in/d7-sr8xR

What are the factors influencing tacrolimus dose-standardized through blood concentration? Pierre Marquet and colleagues developed both clinical and molecular analysis. Let's read more here: https://lnkd.in/deVEJSNg

Advanced Therapy Medicinal Products are transforming organ transplantation with groundbreaking innovations such as gene therapies and tissue-engineered products. But despite their life-saving potential, ATMPs face significant hurdles—regulatory complexities, economic barriers, and uneven access across Europe. The ESOT - European Society for Organ Transplantation ATMP Task Force has just published a comprehensive position paper in Transplant International, outlining key strategies to overcome these challenges: ❗ Streamline Regulatory Processes: Accelerate approvals without compromising safety and efficacy.  ❗ Increase Funding: Prioritize investment in ATMP research and clinical trials to push new therapies forward. ❗ Build Specialized ATMP Facilities: Establish centralized and pre-ATMP facilities for efficient testing, production, and quality control. ❗ Harmonize the Hospital Exemption Pathway: Ensure consistent access to ATMPs for patients with urgent needs across Europe. ❗ Leverage Real-World Evidence: Use robust data to improve treatment outcomes and regulatory decisions. ❗ Engage Patients: Involve patients early to align innovation with real-world needs. These steps are vital to ensuring that ATMPs transition from lab breakthroughs to life-saving treatments. Europe has the potential to lead, but it requires collective action, collaboration, and a shared commitment to innovation. 🙏 A big thank you to the dedicated members of the ESOT Task Force for leading the way in transforming transplantation and ensuring patients gain access to life-saving therapies. 🤝 Together, we can transform transplantation and provide patients with the chance to live. Lorenzo Piemonti Eelco de Koning Sandra Lindstedt Hanne Scholz William Scott Céline Auxenfans Paul R V Johnson Dominique Martin Penilla Gunther Devi Mey Luciano Potena @Olivier Thaunat #ESOT #TransplantInternational #ATMP #Transplantation #Innovation #HealthcareLeadership #PatientCenteredCrae #AccessToCare #BridgeTheGap #ValleyOfDeath #RealWorldEvidence #RegulatoryChallenges #PatientFirst

THE MONDAY MORNING NEEDS QUESTIONS. Could Everolimus be safely used early after transplant? Could MAU868 be safely used for BK Polyomavirus infection? Let's talk with John O'Callaghan and @Simon Knight at TRANSPLANT TRIAL WATCH, in collaboration with ESOT - European Society for Organ Transplantation and @Centre for evidence in transplantation Read more here: https://lnkd.in/d4c9PFZP

This is a great day for DCD Transplantation in Europe! The International DCD Congress & Consensus is kicking off in Bucharest! Opening session DCD Then and Now w/ 🔝 experts discussing key topics 🗣️ DCD History & Future ❓ Why all the fuss? 🔑 Is DCD the main pathway to donation? #DCDcongress follow us for more updates! @BDGuezGil @DrDEMartin @gabriel_oniscu @prof_cillo @nmasnou @edqm_news @ONT_esp @DTI_Foundation @ttsorg STAY TUNED!! https://lnkd.in/ggtWYjc5

Is transplant access the same for all the candidates? The special issue “Diversity, Equity, and Inclusion in Transplantation” was launched by Transplant International to highlight disparity worldwide as a call to raise awereness towards a more equitable program. Take a look at the accompanying editorial here: https://lnkd.in/dTVf6_jY Maria Irene Bellini Paulo Martins MD, PhD, FAST, FEBS, FACS Luciano Potena Chloë Ballesté Delpierre Ifeoma Ulasi Hannah Valantine

Porcine viruses in human recipients? Let's talk here: https://lnkd.in/dttFhajw

The power of the gift

ENJOY THE NEWS! TRANSPLANT TRIAL WATCH The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. This page of Transplant International offers commentaries on methodological issues and clinical implications on two articles of particular interest from the CET Transplant Trial Watch monthly selection. Let's start here: https://lnkd.in/dCxwtuBc