Scientist I - Bioreactor & NGS

Make your mark for patients

UCB's Gene Therapy Vector Core team is seeking a Scientist I - Bioreactor & NGS to join a group focused on AAV upstream process development. The candidate will work across functional teams and will be responsible for bioreactor operations for research grade AAV production to support gene therapy platform development activities; including capsid engineering platform. This is an onsite position and will be based out of our Bedford, MA location,

NOTE: We are interested in every qualified candidate who is eligible to work in the United States. However, we are not able to sponsor visas at any point for this role. This includes taking over sponsorship for an existing Visa.

Major Responsibilities

• Production of AAV vectors using batch or perfumion mode in bioreactors up to 50L
• Characterization of packaged AAV genome by next generation sequencing (NGS)
• Support gene therapy platform development activities by applying upstream expertise
• Good practices of data record keeping
• Collaborate with the vector biology and downstream process development teams
• Ability to function independently and cross functionally across various UCB teams (data scientists, cell biologists, , disease area experts, etc)
  
  

Minimum Requirements

• BS degree in Biology, Biomanufacturing or related field with 8 years of experience - OR - MS degree with 6 years of experience - OR - PhD or Post Doc with relevant academic research experience
• Hands-on AAV experience in industry and/or academia
• Demonstrated past experience of either one of the following skills:
• Upstream unit operation mastery at various scales with biologics or for viral gene therapy applications.
• Next generation sequencing experience for characterization of libraries
• Good communication skills with demonstrated ability to work across disciplines
  

Additional Preferred Experience/Skills

• MS with Biochemical Engineering or Biomanufacturing degree with direct AAV production experience in bioreactors
• 3+ years of experience with process development of AAV vectors
• 3+ years of hands on experience with NGS library preparation, PacBio data acquisition, analysis and QC
• At least 1 year experience in drug discovery in a pre-clinical setting
  
  

Compensation Range

$96,480 to $126,630

If you are interested to learn more about R&D within UCB, please find more information here R&D at UCB .

RANDATUCB

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!

About Us

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 9,000 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?

At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

As an Equal Opportunity Employer, we are open to all talent, and adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on US-Reasonable_Accommodation@ucb.com for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.