4Dcell’s Post

💡💡💡 Don't forget to register for our webinar TOMORROW!💡💡💡 Learn how your existing microscope can be upgraded to the latest confocal or super-resolution system with CrestOptics!

Webinar! It seems almost every lab and imaging facility has a widefield or underutilised microscope - want to know how you can upgrade it to confocal or super-resolution? Sign up to our webinar!

Webinar! May 15, 3PM Melbourne/Sydney/Brisbane time. Do you have an existing microscope? Do you want to know how you can upgrade it to the latest in confocal and super-resolution? Existing microscopes might be optically fantastic, but lack the speed or sensitivity to provide the images researcher require today. CrestOptics have carefully designed their systems to not only offer unparalleled images, but also exceptional flexibility and adaptability. CrestOptics systems are compatible with all of the major research microscope platforms: Leica, Zeiss, Evident and Nikon. Join us to learn how CrestOptics systems can upgrade your existing microscope and provide confocal or super-resolution imaging much more easily than you might think! Hosted by Giulia Ballerin, PhD and Ben Hibbs, this webinar will provide an overview of CrestOptics systems and how existing microscopes from all brands can be easily upgraded. Q&A will be hosted after the webinar for your questions and comments! The webinar will be recorded; please register if you would like a recording after the webinar. CrestOptics are proudly distributed in Australia and New Zealand by Klein Scientific.

#Fast_volumetric_multifocus_structured_illumination_microscopy of subcellular dynamics in living cells "Studying the #nanoscale dynamics of subcellular structures is possible with 2D structured illumination microscopy (#SIM). The method allows for acquisition with improved resolution over typical widefield. For 3D samples, the acquisition speed is inherently limited by the need to acquire sequential two-dimensional planes to create a volume. Here, we present a development of multifocus SIM designed to provide high volumetric frame rate by using fast synchronized electro-optical components. We demonstrate the high volumetric #imaging capacity of the microscope by recording the dynamics of microtubule and endoplasmatic reticulum in living cells at up to 2.3 super resolution volumes per second for a total volume of 30 × 30 × 1.8 µm3." Maximilian Senftleben, Eduardo Hirata-Miyasaki, Hjalmar Brismar, Department of Applied Physics, KTH Royal Institute of Technology, Science for Life Laboratory, Stockholm, Sweden; Antone Bajor, Sara Abrahamsson, Baskin Engineering at UCSC, University of California, Santa Cruz, CA, USA. https://lnkd.in/eKMS--_J

I'm seeing more and more users requesting QC tracking of fluorescence microscopes. How do you know if the microscope you are using has the same performance today as it did last month? Argolight offers a fantastic range of solutions for QC and performance tracking of fluorescence microscopes. ZEISS Microscopy are the latest to announce a partnership with Argolight - who will be next? You don't need an integrated solution - indeed, a separate slide and software is perfect for comparing different systems. Argolight allows you to not only track the performance of a single system, but to also compare systems. Do you need to translate your research onto a different microscope, even from the same manufacturer? Or maybe you want to be sure the microscope is performing in a similar way month to month. Even a manufacturer's annual service may not tell you about the performance of your system at the imaging plane. Argolight will easily let you quantify the difference! Please get in touch if you would like to know more!

Happily I want to share my recent first author publication in Biomedical Optics Express (https://lnkd.in/gfSB-Egj) where we demonstrate our custom built multi-focus structured illumination microscope (MF-SIM) with a unique combination of fast simultaneous 3D recording and super-resolution for imaging of subcellular dynamics. As you can see in the video, the ER structure is highly dynamic as it interacts with many other subcellular structures such as mitochondria and microtubule. The video is a depth-colored max-intensity projection spanning a volume of 30 x 30 x 1.8 µm^3 and was acquired with our MF-SIM at 2.3 Hz. Check out the paper to learn more about the optical path, synchronization between devices and more cool fluorescent images and videos!

🔬 5 Benefits of the Vortran VersaLase Laser Welcome to this week’s #TechTuesdays from Laser 2000 UK! Today, as part of another instalment of our 'Lasers in Microscopy' series, we’re highlighting how the Vortran VersaLase can add value to your microscopy and imaging needs. Here’s why the VersaLase is a game-changer in the world of lasers: 📈 Enhance Your Workflow Efficiency 🎯 Achieve Clearer, More Accurate Results 🧩 Maximise Your Lab Space 🔍 Simplify Your Research Process 🔄 Depend on Consistent, Long-Term Performance Explore these benefits in more detail via the slides below 👇 Ready to find out how the Vortran VersaLase can add value to your microscopy and imaging applications? Contact our experts for more information https://lnkd.in/eD5R9QbZ or visit the product page https://lnkd.in/eRQYuuWX And don’t forget to join us next week for more insights in our #TechTuesdays series! #Microscopy #LaserTechnology #VortranVersaLase #PrecisionImaging #Laser2000UK #L2K #LasersinMicroscopy

Join our hands-on workshop to improve your #CLEM imaging EMBL Heidelberg | 14-15 February 2024 | 10:00 - 17:00 CET We cordially invite you to join our next interactive workshop for correlative microscopy. This #workshop will cover two workflows that allow you to easily incorporate CLEM to get the best quality SEM images of your sample's biological #ultrastructure. See how Coral Cryo, Leica's confocal microscopy workflow with STELLARIS, will allow you to reliably target your area of interest under cryo conditions on grids plunge-frozen with EM GP2 for later inspection with Cryo-SEM. Witness how Coral Life, Leica's solution for Live Cell CLEM, allows time-specific events to be studied with EM resolution with EM ICE high pressure freezing, and better target identification with THUNDER imager, kept under physiological conditions with Samplink all the way to the Electron Microscope. Register here: https://lnkd.in/eXq4An6C

See how Coral Cryo, will allow you to reliably target your area of interest under cryo conditions on grids plunge-frozen with EM GP2 for later inspection with Cryo-SEM #nano #EM #cryo #microscopy #unil #Unige

What could the CELENA S #DigitalImaging System do for your #lab? 👩🔬👨🔬 👨🔬 "It’s easy to use and really useful, I recommend it a lot!" ⭐⭐⭐⭐ 🦠 Application Area: #CellCulture 💬 "The Celena S from Logos Biosystems is a versatile, all-in-one imaging system that combines brightfield, phase contrast, and fluorescence microscopy. Its high-sensitivity camera delivers clear images and makes experiments efficient. The intuitive interface makes it accessible to both beginners and experienced users." https://ow.ly/GkV550TvexI #cellcount #cellcounting #fluorescence #microscopy #labequipment