ADInstruments’ Post

Getting to the Heart of Cardiovascular Research: From Yesterday to Today and Looking Towards Tomorrow In this webinar, Dr. Melanie White presents the various methods for assessing cardiac function in the context of pathology, spanning from in vitro to in vivo techniques, and how she integrates these with cutting-edge mass spectrometry in her research on cardiovascular disease pathogenesis. https://lnkd.in/d66GmcRe

#NEXTWEEK | Dr. Melanie White presents the various methods for assessing cardiac function in the context of pathology, spanning from in vitro to in vivo techniques + more! Engage with a true expert and gain insights that could revolutionize your research! REGISTER HERE: 👉 https://lnkd.in/gSuJuD5Q 👈 🔍 Key Topics Include: ✅ Method considerations to address different biological questions ✅ Tips and tricks for improving success using ex vivo cardiac perfusion ✅ The downstream implications for the various approaches to basic cardiac functional studies #ADInstruments #MakingScienceEasier #CardiacResearch

#UPCOMINGWEBINAR | Getting to the Heart of Cardiovascular Research Dr. Melanie White presents the various methods for assessing cardiac function in the context of pathology, spanning from in vitro to in vivo techniques + more! REGISTER HERE: 👉 https://lnkd.in/gSuJuD5Q 👈 #ADInstruments #MakingScienceEasier #CardiacResearch

#REGISTERNOW | Dr. Melanie White presents the various methods for assessing cardiac function in the context of pathology, spanning from in vitro to in vivo techniques + more! Engage with a true expert and gain insights that could revolutionize your research! REGISTER HERE: 👉 https://lnkd.in/gSuJuD5Q 👈 #ADInstruments #MakingScienceEasier #CardiacResearch

#THISWEEK | Dr. Melanie White presents the various methods for assessing cardiac function in the context of pathology, spanning from in vitro to in vivo techniques + more! Engage with a true expert and gain insights that could revolutionize your research! REGISTER HERE: 👉 https://lnkd.in/gSuJuD5Q 👈 #ADInstruments #MakingScienceEasier #CardiacResearch

Did you miss speaking to our FUJIFILM Cellular Dynamics, Inc team at #SfN2024? No worries, our team will recap our 4 posters in a short webinar. The topics will be: - Optimization of cytokine release assays for iCell® Microglia and the role of healthy microglia and TREM2 variants in neuroprotection and neurodegeneration. - Assays to evaluate iCell Sensory Neurons function and techniques to investigate immune-mediated neuropathic pain and CIPN. - Assessment of the BBB for drug permeability and disease studies in a high-throughput fashion using the iCell Blood-Brain Barrier Kit. - Using Agilent Seahorse XF to detect differences in mitochondrial function between various healthy and diseased iCell neural products. You can register here:

It is important to understand how physical and mechanical forces affect our cells and their micro-environment. Mechanical biomarkers are vital in pre-clinical disease modeling and drug testing, revealing tissue stiffness associated with various pathologies. For example, tumors often show altered stiffness compared to healthy tissue, aiding researchers in understanding tumor progression and treatment effectiveness. Read more:  https://t.ly/PaLs2 What are your thoughts on the role of mechanics in cellular biology? Get in touch:   https://t.ly/8WzwB Optics11 Life provides micro-indentation platforms for mechanobiology research, making it easier than ever to explore the intricate relationship between mechanical properties and disease dynamic. #Pavone #Mechanobiology #Indentation #Fibrosis #BiomedicalResearch

👉 Make sure to attend Niels Vande Casteele presentation on "Spatial Transcriptomics of Crohn’s Disease Recurrence" at #TRICON today. Niels will be reviewing @AcelaBio validated GCP/GcLP compliant end-to-end 10X Visium spatial transcriptomics workflow from sample processing to bioinformatics analysis. 📑 A case study will also be presented on how formalin fixed paraffin embedded mucosal tissue biopsies were analyzed and spatial transcriptomics data were used to investigate disease recurrence in IBD patients. #Acelabio #SpatialBiology #PrecisionMedicine #Biomarkers

⭐TANGO2 Family Conference Speaker Spotlight!⭐ Dr. Li is a tenured Associate Professor in the Department of Medicine at Baylor College of Medicine. Her primary research objective focuses on unveiling the intricate molecular mechanisms underlying cardiac arrhythmias. The team employs genetically modified mouse models to elucidate the molecular mechanisms of common and rare forms of cardiac arrhythmias. #TANGO2ResearchFoundation #TANGO2FamilyConference2024 #TANGO2Disease

https://lnkd.in/gcPEkS4f Many years in the making - my first academic publication is now available for reading (open access) in Fluids and Barriers of the CNS! Many thanks to my UBC colleagues from the Michael Underhill lab who helped me put this together! Some fun highlights; 1) Novel sub-populations of blood vessel-associated cells (fibroblasts) can be found in the distinct "leaky" vasculature of the choroid plexus and pituitary gland 2) These novel fibroblasts are far more abundant in these regions than fibroblasts in the rest of the brain 3) Distinct transcriptomic markers define these sub-populations, including but not limited to CD34, claudin-11, GPR88, Tcf21 and alkaline phosphatase 4) Indole-n-methyltransferase, the putative DMT-synthesizing enzyme, is found exclusively in fibroblasts within the brain and is concentrated in the choroid plexus and pituitary gland (and is mostly absent from pinealocytes).