Akoya Biosciences, Inc.’s Post

The 2024 Nobel Prize in Physiology or Medicine honors Drs. Victor Ambros and Gary Ruvkun for their groundbreaking work with the tiny roundworm C. elegans. Their research on microRNA transforms our understanding of cell communication and has important implications for diseases like Alzheimer’s and cancer.   Learn more about their incredible achievements and the vital role of animal research in advancing medical science!🐍🔬 https://lnkd.in/eHsd-5Bm   #NobelPrize #AnimalResearch #Celegans #MedicalScience

🔬✨ Exciting Research Alert! ✨🔬https://lnkd.in/dUD94a5X latest publication in the Journal of Biological Research sheds light on innovative strategies for understanding and combating Glioblastoma multiforme (GBM), the most common primary brain tumor known for its aggressiveness and resistance to conventional treatments. 🧠💥GBM's complexity demands advanced research models, and our study explores a range of in vivo and in vitro approaches. From traditional xenograft mouse models to cutting-edge 3D in vitro models like spheroids and organoids, we're breaking new ground in understanding GBM's inner workings. 💡Our research not only delves into the intricacies of these models but also critically evaluates their advantages and limitations. By leveraging these advanced tools, we're gaining deeper insights into GBM biology, paving the way for more effective treatments and improved patient outcomes. 💪🔍Stay tuned for more updates as we continue our journey towards unraveling the mysteries of GBM and developing better strategies to combat this challenging disease! 🚀 #GBMResearch #InnovationInScience #BrainTumorAwareness #JournalOfBiologicalResearch Società Italiana di Biologia Sperimentale

Hello from Ghent! VIB #SpatialOmics24 is all about, you guessed it, #spatialbiology… and all of the latest spatial technologies that allow researchers to accurately map the role of each cell in a sample, which in turn, can help predict disease outcomes or immune response to a novel therapy. Imaging Mass Cytometry™ is one of these technologies, clearly defining areas in any tissue type ― including lung, bone marrow, colon and brain ― without background autofluorescence or spectral overlap. Hester Koppejan covered applications that benefit from this approach in today’s talk: High-plex whole slide spatial biology assays for clinical translational research powered by the Hyperion XTi™. More on the event: https://lnkd.in/etxs2CMk More on #spatialbiology: https://lnkd.in/g8aHFdSF #clinicalresearch #immunology Roberto Spada Sandra D.

We're excited to share recent CellScape data from our very own Kayla Cashion showing the tissue microenvironment of rectal #adenocarcinoma. By leveraging our #VistaPlex Architecture Kit, Kayla was able identify and visualize key mucosal components within the #tumor #microenvironment. Epithelial Cells: The intestinal crypts show striking expression of E-cadherin (green) and β-catenin (magenta), highlighting the structural integrity of the epithelium. Lamina Propria: Supported by smooth muscle cells marked by alpha-SMA (cyan), the connective tissue is rich in vasculature (CD34 in yellow) and abundant #plasma cells (CD138 in red) that play crucial roles in gut #immunity. DNA Visualization: The cellular architecture is further detailed with blue #DNA staining, allowing us to delve deeper into the cellular landscape with the CellScapes single-cell resolution. Stay tuned as we continue to uncover the complexities of cancer biology. Learn More about CellScape Here: https://lnkd.in/gRFpv6kT Learn More about our VistaPlex Assay Kits: https://lnkd.in/e-5VV7Cr #CancerResearch #RectalAdenocarcinoma #Immunology #Histology #Pathology #SingleCell

Read highlights in this week’s issue of PNAS: We investigate mismatches between plant green-up and bird migration, explore how fossils illuminate ancient mating behavior, and discover the genomics of Tasmanian devil cancer. https://ow.ly/7rkQ50R00Fh

🌟 Postdocs are the unsung heroes of research integrity, playing a vital role in shaping a healthy research culture.    🔬 In the latest #ResearchIntegrity column, Andrew Porter from the Cancer Research UK Manchester Institute explores the crucial role postdocs play in contributing to research integrity. From training new lab members and embracing open science practices to championing transparency in methodology, postdocs provide much of the fabric that underpins research integrity 💡    Read the full blog 👉 https://bit.ly/3TxvTla

Check out this interview clip from the Humans in Space Challenge! Hopefully a full-length one is in the works where you can hear my thoughts on the future of human spaceflight (it involves developing and using cosmic radiation countermeasures) 😁

Check the impressive list of international speakers!

Steroid Hormones and Receptors (SHR) 2024 Abstract Submissions    We are welcoming abstract submission through the deadline of Sunday, September 1: https://bit.ly/3WA6A3O The goal of SHR 2024 is to present and discuss advances in steroid hormone action in biology and medicine, exploring their role in biology, chemistry, pharmacology, oncology, neurology, metabolism, cardiovascular biology and endocrinology. Sessions will cover (but are not limited to) the following topics:  ·        Cancer Biology and Therapeutics  ·        Cardiovascular Biology and Disease  ·        Neurobiology and Aging  ·        Metabolism and Comorbidities  ·        Molecular and Structural Biology of Steroid Receptors  ·        Immune System and Inflammation  ·        Systems Biology and Cell Signaling Networks The conference will feature Plenary and Keynote Lectures, oral presentations and posters by prominent and emerging leaders as well as trainees in the field. Conference proceedings will be published in an international peer-reviewed journal.    #SHR2024 

Lab Spotlight: Dr. Lingyan Shi at UC San Diego Dr. Lingyan Shi’s lab focuses on bioorthogonal chemical bond imaging of complex molecular events during aging and disease progression. This work aids in disease detection, diagnosis, and understanding neurodegenerative diseases, cancer, and aging processes. Using the Compresstome Vibratome Dr. Shi’s lab uses our Compresstome vibratome for precise tissue slicing, producing high-quality sections for imaging and analysis. “My students and postdocs have generated impressive results with this instrument,” notes Dr. Shi. Read the full article to learn more about Dr. Shi’s research: https://lnkd.in/edXSmCvF #PrecisionaryInstruments #compresstome #microtomes #vibratingmicrotomes #vibratomes #tissuesectioning #precisioncuttissuesslices #tissueslicing #laboratoryequipment #labsolutions