AOCS’ Post

How do you choose a favourite ingredient? It's tough, but we narrowed the list to these Top 5 Anti-Aging Hero Ingredients for your upcoming formulation. AvenaPLex is a complex of skin-identical lipids, including ceramides, phosphatidylcholine, and phosphatidylethanolamine, which provide both short-term and long-term protection of aged skin. Phyto-Biotics Acai® takes advantage of the specific activity provided by Ferulic Acid to provide formulators with a plant-derived stem cell ingredient capable of imparting anti-aging, antioxidant, and anti-wrinkle properties. It also reduces harmful damage to collagen by preventing harmful enzymatic activation while enhancing ATP synthesis and cellular metabolism. AC ExoRestore—As we age, collagen naturally decreases, resulting in sagging, wrinkles, and fine lines. Fibroblasts treated with AC Exorestore showed increased collagen synthesis, thereby effectively improving normal skin aging, collagen thickness, and collagen density. Nikkol VC-IP VS is an oil-soluble Vitamin C that is stable against high temperatures, making it easier to use in formulations. ABS Viola Tricolor Extract PF may be used to increase the concentration of hyaluronic acid within the epidermis to enhance the skin’s water-binding properties, as well as increase the synthesis of the CD44 membrane receptor, which binds hyaluronic acid in the skin. Samples and specs are available for our ANZ clients. Drop a yes below or reach out to your Ceechem Account Manager, who will get these organised quickly.

The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes a very interesting open access article https://lnkd.in/eHM7AHhu #cosmeticscience #antiinflammatory #sunprotection #uvdamage

"Excited to introduce Ecosave HAP Pro! 🌿 This multifunctional cosmetic ingredient is a game-changer for odor-sensitive and baby care products. Hydroxyacetophenone (HAP) not only offers strong antioxidant and broad-spectrum antimicrobial benefits but also helps regulate inflammation. Perfect for keeping your formulations safe and effective while maintaining a gentle touch. #Cosmetics #Skincare #NaturalIngredients #BabyCare #Antioxidants"

👉🏼 Enzymatic synthesis of a skin active ingredient - glochidone by 3-ketosteroid dehydrogenase from Sterolibacterium denitrificans 🤓 Agnieszka M Wojtkiewicz 👇🏻 https://lnkd.in/e9RSDnGZ 🔍 Focus on data insights: - AcmB2 catalyzed the oxidative dehydrogenation of 3-ketolupeol to yield glochidone with >99% conversion efficiency and 100% regioselectivity. - Investigation of biochemical attributes of the enzyme, including electron acceptor type, concentration, and steroid substrate specificity. - Assessment of antioxidant and rejuvenating properties of glochidone compared to lupeol and reference compounds. 💡 Main outcomes and implications: - Glochidone demonstrated robust rejuvenating properties and inhibition of elastase and collagenase, indicating its potential in skincare formulations. - The study presents novel enzymatic pathways for bioactive compound synthesis using 3-ketosteroid dehydrogenase from Sterolibacterium denitrificans. 📚 Field significance: - Potential applications of glochidone in formulations addressing skin health concerns. - Exploration of unique substrate specificity of AcmB2 and related enzymes in the 3-ketosteroid dehydrogenase family. 🗄️: #enzyme #skinhealth #bioactivesynthesis #3ketosteroid

Introducing Ecosave HAP Pro, INCI: Hydroxyacetopheone An antioxidant, multifunctional, broad-spectrum antimicrobial cosmetic ingredient, great for odor-sensitive cosmetics and baby care products. HAP naturally exists in the stems and leaves of the Asteraceae plant Artemisia annua, as well as in the roots of plants such as Artemisia scoparia, Asclepiadaceae, and Panax ginseng. Due to the presence of phenolic hydroxyl groups, HAP has certain antioxidant properties and is commonly used as an antioxidant. HAP can regulate the activity of COX-2 enzyme, a key inflammatory response factor. We make Ecosave HAP Pro specifically for odor-sensitive cosmetics. Source: Chang CW, Chen YC, Lin YC, Peng WH. (2017). p-Hydroxyacetophenone suppresses nuclear factor-κB-related inflammation in nociceptive and inflammatory animal models. J Nat Med. 71(2): 422-432. doi: 10.1007/s11418-017-1074-9

The all new formulation of Hyaluronic treatment in high & low molecules with vitamin B3

" Beautiful Molecular For personal care " **************************************** #Lauric Acid Emulsifier: # Lauric acid is used as an intermediate and surface-active agent in industry and in the manufacture of personal care products in the consumer market. lauric acid as dodecanoic acid, apart from being a saturated fatty acid. It is as a bright white, powdery solid with a faint odor of baby oil or soap. Also, we may also term the salts and esters of lauric acid as laureates. This acid has its origin in various vegetable fats, particularly in coconut and palm kernel oils. Apparently, lauric acid makes its availability less expensive as compared to many other fatty acids. It even provides a long-shelf life, it is considered as nontoxic and safe for handling. Besides, lauric acid acts as an emulsifier for the production of various personal care formulation It helps in producing soaps and cosmetics as it reacts with sodium hydroxide to give sodium laureate, which is a soap. Most commonly, we get sodium laureate by saponification of various oils, such as coconut oil. These precursors give mixtures of sodium laureate and other soaps. Further, lauric acid has medicinal use for treating different diseases. It helps in treating viral infections like influenza, swine flu, the common cold, and others. Lauric acid also benefits from treating bronchitis, yeast infections and other intestinal infections like ringworm. Similarly, lauric acid provides full antibacterial and anti-inflammatory actions to treat various diseases. With such effects, it becomes more beneficial in personal products for skin repairing and as an anti-acne agent. ############## Further, lauric acid fuses to the bacterial membrane of acne bacteria, keeping it from proliferating and reducing inflammation from acne. We often use it at higher levels to impart a pleasant natural fragrance and use it in cosmetic formulations as a solubiliser in emulsions.

Rousselot's collagen peptide, Peptan, was found to boost the skin's elasticity, hydration and density, whilst also diminishing visible wrinkles in middle-aged participants. In a further study, the #bioavailability of #collagen with a range of different molecular weights from three different animal sources were put to the test, finding that the active ingredient absorption was consistent over all the types tested. #skinhealth #beautyfromwithin #nutraceutical #functionalingredients https://lnkd.in/evmZ3Yn5

Advantages of liposome cosmetics for use on the skin. The application of liposome preparations on the skin has the following advantages: ① Long-lasting sustained release: Lipids similar to sebum (such as sphingomyelin) form liposomes that are highly similar to the lipids in the stratum corneum of the skin, providing space for the storage of active ingredients in the skin and increasing local accumulation; ② Effectiveness: The active ingredients are encapsulated by liposomes to avoid degradation or decomposition by light; ③ Targeting: After surface modification, liposomes can have targeted drug delivery characteristics; ④ Skin nutrition and health care effects: Liposomes can play a role in moisturizing, anti-oxidation, softening the skin, and nutritional supplementation in cosmetics. #liposome #skincare #cosmetics #antioxidation #moisturizing #activeingredients https://lnkd.in/gmrWk8vw

Oral supplementation of Ilex paraguariensis extract and eggshell membrane exhibit beneficial effects on the skin of mature male rats