Association of Pediatric Hematology/Oncology Nurses (APHON)’s Post

This is a great article about some of the discoveries taking place in Low Earth Orbit (LEO) using the Life Science Glovebox (LSG) managed by the Tec-Masters, Inc. (TMI) team!

Label-free live cell imaging technology 🔍 Here capturing two glioblastoma cells undergoing autophagy, revealing all the intricate details of the process.

New rapid learning module released from the Cancer Institute NSW eviQ Education program developed in partnership with our clinical experts. To mark World Infertility Awareness Month this June, we have released a new rapid learning highlighting recommendations from the COSA guidelines for fertility preservation for people with cancer. The guidelines point to an underimplementation of fertility preservation care, partially due to a lack of awareness from health professionals about the vital role they play. The new mini-module seeks to fill this gap and support your understanding of the impact of cancer treatment on fertility and fertility preservation options for patients with cancer in your care. The five minute eLearning includes three cases studies, and will support you to be able to: 1) outline the impact of cancer treatment on fertility, 2) identify fertility preservation options  and 3) describe your role in fertility preservation care. #cancer #nursingeducation #evidenccebasedcare #cosa https://lnkd.in/gS_A9vAf

𝐀𝐮𝐭𝐨𝐩𝐡𝐚𝐠𝐲: 𝐚 𝐛𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐩𝐫𝐨𝐜𝐞𝐬𝐬 𝐨𝐟 𝐜𝐞𝐥𝐥 𝐝𝐞𝐚𝐭𝐡 𝐨𝐫 𝐜𝐞𝐥𝐥 𝐬𝐮𝐫𝐯𝐢𝐯𝐚𝐥 ❓ Autophagy is a cellular process essential for the maintenance of cellular homeostasis that involves the degradation and recycling of damaged organelles, proteins and other cellular components. Excessive autophagy can lead to cell death whereas dysregulation of it can be implicated in various diseases, including Alzheimer's and Parkinson's disease, or can even promote cancer cell survival. This video captures glioblastoma cells undergoing autophagy upon drug induction. At Nanolive, our label-free technology provides unique insights into the dynamic process of autophagy, capturing key steps such as engulfment of cytoplasmic materials, increase in vacuolation, organelle degradation, cell shrinking and cell to cell interactions. Understanding the dual role of autophagy in health and disease can help in the development of more targeted therapeutic strategies. Learn more about our technology : https://bit.ly/3N3QtpM #Nanolive #Microscopy #CellImaging #LabelFreeTechnology #HealthandDisease #AutophagyResearch #TargetedTherapies #Cancer #NeurodegenerativeDiseases 

Childhood cancers are a devastating reality for many families around the world, and on #RareDiseaseDay, it is crucial to shed light on these often overlooked conditions that affect our youngest and most vulnerable population. These diseases, although rare in comparison to adult cancers, have a profound impact not only on the children diagnosed but also on their families and communities. Children battling #cancer endure immense physical and emotional challenges. The aggressive nature of some childhood cancers requires intensive treatments like chemotherapy, radiation therapy, and surgery. These treatments can have long-lasting effects on a child's development and overall well-being. Research into childhood cancers is crucial to improve treatment outcomes, reduce side effects, and ultimately find cures for these diseases. CancerModels.Org has the largest open collection of #pediatric patient-derived #xenograft (PDX) models and associated data available for the research community to facilitate #rarecancer research and development of personalized treatments. #rarecancer #cancerresearch #cancermodels #raredisease #personalisedmedicine #precisiononcology

Just published with Nature Portfolio - "The coexistence of a BRCA2 germline and a DICER1 somatic variant in two first-degree cousins suggests their potential synergic effect" 🗨️We reported for the first time the occurrence of two #neoplasms typical of DICER-tumor predisposition syndrome in two patients carrying the same germline #BRCA2 variant and a somatic #DICER1 mutation. These findings suggest a potential cooperative tumorigenic role of DICER1 and BRCA2, both implicated in #DNA repair pathways. This study demonstrates the importance of studying #BRCA variants in the #pediatriccancer patient population for the potential screening, risk-reduction interventions, and family planning options currently available for relatives of children carrying BRCA mutations.  Extending the analysis of these genes to the pediatric population could provide relevant insights correlated to a possible predisposition to #cancer. Special thank you to "Il Coraggio dei Bambini" Foundation for the funding and never-ending support. 🎗️ Giada Del Baldo, Selene Cipri, Marta Matraxia, Antonio Novelli, Antonella Cacchione, Annalisa Serra, Andrea Carai, Luigi Boccuto, Stefania Colafati, Pier Luigi Di Paolo MD, PhD, Evelina Miele, Sabina Barresi, rita alaggio, Isabella Giovannoni https://lnkd.in/dvfGJi3p #goldseptember #hereditarycancer #childhoodcancer

Don't miss our live #webinar on von Hippel-Lindau disease (VHL) management, presented by Eric Jonasch, MD, Professor of Medicine, The University of Texas System, MD Anderson Cancer Center. 📅 Register now to save your seat and hear critical insights on why #VHL Education is vital for #clinicians. Click the link to register today! https://bit.ly/45uYhcu #healthcare #medicaleducation #HealthcareWebinar #cme #NCPD #CE #healthcareprofessionals #medicalgenetics #geneticcounseling #genetics #GeneticCounselor #GeneticResearch #geneticsresearch #oncology #oncologists #nursepractitioner #physician #physicianassistant #nurse #oncologynurse #raredisease

https://lnkd.in/gYyNgzzZ Article title: Brucellosis in Immunocompromised Hosts Author(s): KA Al-Anazi; AM Al-Jasser Journal: Archives of Organ Transplantation Journal ISSN: 2640-7973 Abstract: Recently, the incidence of brucellosis in immunocompromised patients has increased due to the parallel increase in the number of individuals with low immunity such as cancer patients and recipients of stem cell and solid organ transplantation. Additionally, the immunity of pregnant females is reduced and this makes them more susceptible to infections by various microorganisms including Brucella species. #ArmTransplant #BoneMarrowTransplant #BrainTransplant #CornealTransplant #DoubleLungTransplant #EyeTransplant #EyeballTransplant #EyebrowTransplant #FaceTransplant #FacialHairTransplant #FecalTransplant #HairTransplant #HeadTransplant #IntestineTransplant #IsletCellTransplant #KneeTransplant #LungTransplantation #NeuralTransplant #OrganDonation #OrganTransplant #Peertechz #PeertechzPublications #OpenAccess #ScientificJournals #PeerReviewedJournals #OpenAccessPublishers #OvaryTransplant #PancreasTransplant #PediatricTransplant #PenisTransplant #RenalTransplant #RetinalTransplant #SkinTransplant #ThymusTransplant #TissueTransplant #UterusTransplant #WombTransplant

https://lnkd.in/gkUG4bFw Article title: A Rare Benign Pancreatic Lesion Mimicking Malignancy- Eosinophilic Pancreatitis   Author(s): Kurşat Rahmi Serin; Muharrem Oner; Nadir Adnan Hacım; Ali Emre   Journal: Archives of Clinical Gastroenterology   Journal ISSN: 2455-2283 Abstract   Background: Eosinophilic infiltration of the pancreas is usually associated with generalized diseases like "sclerosing pancreatitis", "eosinophylic gastroenteritis" and "systemic mastocytosis". Most patients have systemic findings such as eosinophilia, elevated IgE levels and gastrointestinal tract infiltration Isolated eosinophilic infiltration of the pancreas is much less common and is usually found in the histological evaluation of pancreatic specimens resected with the misdiagnosis of pancreatic cancer. #Eosinophilicpancreatitis #Malignancy #Pancreatoduodenectomy #InflammatoryBowelDisease #FunctionalGIDisorders #GastrointestinalAndLiverDisease #DigestiveOncology #GastrointestinalSurgery #PediatricGastroenterology #ColorectalCancer #PancreaticCancer #HepatocellularCarcinoma #GastrointestinalBleeding #Endoscopy #Peertechz #PeertechzPublications #SurgicalGastroenterology #StomachUlcers #VirtualColonoscopy #GastricUlceration #RouxenYGastricBypass #GastricAcidSecretion #GastricMucosa #GastricUlcerHealing #GastricCardiaCancer #ReproductiveEndocrinology #EndocrineDisorders #Hepatology #AlimentaryCanal #PancreasCancer

#leukemia Results pertaining to leukemia indicated that children residing within 50 m of power lines had a greater chance of developing leukemia (OR 3.05; CI 0.97–9.55). It's crucial to remember, though, that this evaluation was based on a very limited sample—just 12 cases. Examining the relationship between land use and childhood leukemia and lymphoma in Tehran https://lnkd.in/ersxzUUa