Artinis Medical Systems’ Post

GOLD MEDAL MEDICINES: Having my research roots in molecular exercise physiology, watching the Olympic games is always extremely exciting and thought provoking for me. Beyond its role in winning gold medals, exercise, when reduced to a molecular level, simply represents bioenergetic and mechanical stresses for the body. However, the clinical implications and benefits of the molecular response to exercise represents a well of knowledge for developing therapeutics for cardiovascular, metabolic, and neurological disorders. Exercise mimetics are one proposed class of therapeutics that specifically mimic or enhance the beneficial effects of exercise for individuals who may not have the ability or capacity to participate in sufficient levels of physical activity. While replacing exercise with a single pill would be an Olympic feat, building a detailed understanding of the molecular pathways that are altered by exercise is crucial for revealing adaptive cellular responses that can be leveraged to develop therapies that mimic specific aspects of exercise. Collaborative efforts, such as the NIH established Molecular Transducers of Physical Activity Consortium (MoTrPAC), and industrious webtools, such as MetaMEx, are striving to create molecular maps of exercise responses across organ systems which could lead to development of initial mimetic candidates. Yet, much like the precise physical demands and adaptations necessary to succeed in specific sports, the demand for exercise mimetics will also need to take a precise approach for specific disorders. Until then, studying high performance physiology will be the training that leads scientists to gold medal medicines. #Olympics #Exercise #Health #PrecisionMedicine

2nd Weekly Seminar at EuroMov Digital Health in Motion Université de Montpellier IMT Mines Alès 👏 Many thanks to Olivier Dupuy (#MOVE Université de Poitiers) for his visit and his excellent presentation on "Heart-brain relationship: effect of physical exercise". 🧠 📈 📉 🚶♂️ #cognition #NIRS #exercise #HRV #cerebrovascular #oxygenation #elderly #fitness #executive_function #performance ✅ A great lesson in exercise physiology, integrating the co-operating muscular, cardiorespiratory and brain systems during exercise ✅ Some stimulating discussions with PhD candidates

What is Exercise Physiology? What are the main goals of Exercise Physiology? What is the difference between Exercise Physiology and Physiotherapy? Our clinical team answer all these questions so you can make an informed decision about your health. https://hubs.la/Q02gr0hV0

Excited about the fascinating world of NIRS and its underlying principles that drive effective muscle imaging? Let's dive into the compelling topic of Near Infrared Spectroscopy, something you will find quite intriguing and highly beneficial once grasped. 💡 Firstly, it’s essential to understand what NIRS is and how it works. NIRS is all about using wavelengths of light within the range of 700-900nm to measure tissue oxygenation and hemoglobin content in the body. This non-invasive technique helps us to monitor muscle oxygenation and blood flow, providing valuable insights into muscle function, using something as simple as light! Now, here comes the fascinating part─ the modified Beer-Lambert law. This principle is like the secret sauce that makes NIRS so effective. 🍔 It enables us to calculate changes in oxygenated, deoxygenated, and total hemoglobin and myoglobin levels within a muscle, through optical means. While NIRS may struggle to differentiate between these molecules at times, it still gives us the crucial measurements we need to understand muscle activity and performance. However, like any superpower, NIRS has it's own limitations too. One-dimensional NIR SDCWS (single-distance continuous-wave spectroscopy) can sometimes be restrictive. Fortunately, with the aid of time-resolved and phase-modulated light sources, these limitations can be overcome. These advanced variations of NIRS technology provide more comprehensive and detailed muscle imaging capabilities, making it a superhero in the world of sports science, exercise physiology, and clinical diagnostics. The potential for NIRS in muscle imaging is boundless, and it's a perfect example of how technology can revolutionize the way we understand and measure physiological functions. Stay tuned in, keep learning and exploring, and you'll soon be at the frontier of this exciting field! #NIRS #MuscleImaging #Innovation #SportScience

Ever wondered how you can accurately assess muscle oxidative metabolism without relying on invasive methods like microelectrodes or Positron Emission Tomography? The answer lies in Near Infrared Spectroscopy (NIRS), a non-invasive and portable technique that has been revolutionizing research methods in exercise and athletic performance over the years. NIRS is like a fitness tracker for muscle metabolism - efficient, convenient, and precise! 💪🔬 Let's dive deeper into the practical use of NIRS and how it stacks up against other conventional methods. NIRS offers the advantage of being non-invasive, meaning it can be used frequently on different populations without causing discomfort or trauma. This makes it particularly valuable when conducting field studies or research on athletic performances. Imagine being able to monitor the muscle oxygenation levels in a marathon runner without interrupting their race. That's the true power of NIRS! 🏃 Now, let's compare NIRS with another non-invasive method like Magnetic Resonance Spectroscopy (MRS). While MRS is highly accurate, it's not exactly portable or convenient. Athletes can't carry an MRI machine around in their gym bags, can they? Additionally, methods like Doppler ultrasound, while accurate, are not entirely non-invasive and lack portability. On the other end, if we compare NIRS with invasive methods like microelectrodes, myoglobin saturation, or NADH analysis, the need for incisions, blood sampling or skin penetration alone makes these methods less preferable, especially for frequent measurements or studies in diverse populations. As research managers, directors or founders, adopting NIRS for such studies can minimize the physical and logistical hurdles in your research projects, facilitating quicker and more accurate assessments. 📊 In conclusion, the practical use of NIRS in assessing muscle oxidative metabolism, stands out as being both non-invasive and portable, making it a go-to tool for efficient, frequent, and less intrusive measurements. It's a great example of harnessing technological advancements to enhance our research methodologies and get closer to unlocking the unlimited potential of human performance. Let's keep innovating with NIRS and other tools, and together, we'll take the research world by storm! 🌪️ #PracticalUseofNIRS #CuttingEdgeResearch #MuscleMetabolism

A groundbreaking study led by the University of Barcelona introduces a new technique for accelerating muscle injury recovery, which is key for elite athletes. By intermittently exposing muscles to low oxygen levels in a simulated high-altitude setting, researchers have observed remarkable results. This innovative approach, centered around load management and hypobaric hypoxia, holds immense promise for athletes and active individuals seeking faster, more effective recovery. 💪🔬 #Recovery #LoadManagement #Innovation #eliteathletes https://lnkd.in/dn_ss86X

Very excited to see this research on Iron Bodyfit and Miha Bodytech Equipment by Mayo Clinic!!   The Mayo Clinic's study on Whole Body Electronic Muscle Stimulation (WB-EMS) using miha bodytec equipment was a comprehensive 16-week randomized controlled trial. It demonstrated that WB-EMS is effective in improving key health markers. The study, focused on 41 patients, highlighted the efficiency of WB-EMS in enhancing cardiovascular, metabolic, and biomechanical health compared to conventional training. This form of training, involving electrical impulses to stimulate muscles, proved to be a time-efficient method for achieving significant health benefits. Key findings from the study include: Reduced waist-hip ratio, indicating improved body composition. Significant reduction in total cholesterol levels. Enhanced anaerobic capacity, beneficial for quick energy bursts. Improved breathing efficiency, contributing to better aerobic conditioning. Increased maximum peak force, aiding in stability and strength. Elevated rate of force, leading to improved stamina and core strength. Better endothelial function, indicating improved blood flow. This research positions WB-EMS as an innovative and effective approach to physical training, offering substantial health benefits in a time-efficient manner. For detailed insights, refer to the full study on the Elevate website Mayo-Clinic Releases New Study on the Positive Health… | Elevate (elevatearena.com)

🧠 Delighting to share our new insights into Exercise Neurophysiology! 💡 In this exciting study that I coauthored ("Cerebral and Muscle Tissue Oxygenation during Exercise in Healthy Adults: A Systematic Review" in press at Journal of Sport and Health Science - IF 12.2), we integrated findings from 20 studies that utilized Near-Infrared Spectroscopy (NIRS) to measure muscle and cerebral oxygenation responses during exercise. 🏋️♂️ Here are the key highlights: 🔬 Findings consistently reveal greater muscle deoxygenation during exercise, reflecting increased oxygen utilization. 💔 Muscle oxygen availability is compromised at exhaustion, reducing blood flow and oxygen extraction. 🧠 Cerebral tissue experiences heightened oxygen delivery with increased exercise intensity, suggesting intense brain engagement. 🚫 At exhaustion, cerebral oxygenation plateaus or declines, potentially leading to motor failure. The verdict? Exercise triggers muscle O2 utilization and brain O2 delivery, but exhaustion marks a critical point where both systems face compromise. A must-read for anyone interested in the dynamic interplay between our brain and muscles during physical activity! 💬📚 #ExercisePhysiology #ResearchInsights #BrainAndMuscle #ScienceBreakthroughs Link: https://lnkd.in/d7ycCUej Diego Orcioli-Silva; @Victor Spiandor Beretta; @Felipe Marroni Rasteiro; Anita B Marostegan; Rodrigo Vitorio; Claudio Gobatto; Fúlvia Manchado Gobatto Acknowledgments: FAPESP; CNPq; UNESP - Universidade Estadual Paulista "Júlio de Mesquita Filho"; Ciência Pioneira

I know in NZ Exercise Physiology is still quite new to a lot of people. Sooo if you are wondering what exactly an exercise physiologist does, then have a read of Specialised Healths latest blog which sums it up nicely! If you have any questions or want to know more after reading this please feel free to reach out!

For those of you working in clinical exercise physiology. What are your thoughts on the future? What have been your greatest challenges? Do you enjoy working in the field of clinical exercise physiology. What advice would you have for someone interested in clinical exercise physiology?