Arvinas’ Post

New paper out! Great work by María Fernández Álvarez, Pilar Horcajo, Alejandro Jiménez Meléndez, Pablo Angulo Lara, Ana Huertas López, Paco Huertas López (Marbyt | Smart Solutions for Biotecnology), Ignacio Ferre, Luis Miguel Ortega Mora and Gema Alvarez García. We performed a transcriptomic analysis of Besnoitia besnoiti-Infected Fibroblasts to understand the molecular basis behind the drift to fibrosis during the disease progression. Read more here https://lnkd.in/dAAktYs9 #mdpimicroorganisms

Fantastic podcast discussing recent advances and opportunities in the largest disease category, CNS diseases. Recent failures, especially in ALS, offer new insights to optimize the next wave of treatments. "If there is data and need - there is opportunity." #Biotech #Neurodegenerativediseases #ALSAwareness #Neurizon

Today is World Cholangiocarcinoma Day. It's a day to "raise much-needed awareness" of CCA & advocate for a "smoother journey to diagnosis," according to the Global Cholangiocarcinoma Alliance. Don't miss this insightful new article on CCA by our contributor Amanda Brink, DNP, APRN, FNP-BC, AOCNP, who discusses the importance of molecular testing for these patients: https://buff.ly/49gUZKK #WorldCCADay #BeClearOnCCA

On the 75th anniversary of the World Health Organization World Health Day we join with others to both celebrate the advances being made in improving healthcare worldwide, to recognize the challenges that remain, and promote the right to good health for all. #MyHealthMyRight Mitochondria are fundamental to life and impact the health of our cells. Vandria is at the vanguard of mitochondrial therapeutics developing novel medicines with potential across many disease areas, including age-related and chronic diseases. Capitalizing on 15 years of discovery science, we have a pipeline of first-in-class mitophagy inducers that help rejuvenate cells. Our lead candidate, VNA-318, is a brain-penetrant, patent-protected, #mitophagy inducer which has been shown to acutely improve memory and learning, and to have strong disease-modifying effects in models of #NeuroDegenerativeDiseases such as #Alzheimer’s and #Parkinson’sDisease. VNA-318 is expected to enter the clinic this summer. More information on our science and portfolio HERE www.vandria.com #WorldHealthDay #MitochonrialTherapeutics #DrugDevelopment

Precision Medicine Online interviewed DELFI CMO Peter B. and President & COO Jenn Buechel for an article on #DELFI’s partnership with Indigenous Pact PBC, Inc., a company focused on improving healthcare delivery for Indigenous Americans, on a program bringing our blood-based cell-free DNA fragmentomics assay to aid lung cancer screening, the FirstLook Test, to rural Native American communities. According to Kurt Brenkus, CEO of Indigenous Pact, some rural tribal health systems don't have LDCTs, meaning patients need to travel to another health system, sometimes hours away, to get a lung cancer screening. "American Indians and Alaska Natives have the highest health disparities out of any population in the United States, and cancer is no exception. The fact that this small blood test can be transported into these rural areas and be administered through a primary care setting is a game-changing technology." DELFI’s CMO, Peter B. Bach said "By working with Indigenous Pact, we hope we can help improve lung cancer screening rates in the Native community where lung cancer has the greatest burden." This sentiment echoes DELFI's fundamental goal of making lung cancer screening more accessible to all. Click here to read the article: https://bit.ly/3z97M4P #earlyscreeningsaveslives #lungcancerscreening #indigenouspact #LDCT

A rare disease is defined as affecting fewer than 1 in 2,000 people - stunting researchers' ability to understand these diseases due to the scarcity in diagnosis and limited research opportunities. CMI's model aims to change that by enabling all cancer patients regardless of where they live or have been treated in the US and Canada to share their experiences, medical histories, and biological samples with the research community across the world. Learn more about our mission at JoinCountMeIn.org. #RareDiseaseDay #CountMeIn

👴 👵“Forever young?” Targeting the hallmarks of aging   This year Fernanda Ricci, PhD attended the Longevity Summit in Milan (March 2024), alongside peers and international experts, with the main focus on biological control of aging and groundbreaking therapeutics. During this fascinating meeting there were numerous highlights of promising therapies for aging and age-related diseases. Check below the key insights that caught Fernanda’s attention at the conference! 🗝 Key takeaway: Aging is under biological control. By identifying the pathways that regulate aging, we can develop therapeutics to delay aging and mitigate age-related diseases. 📹 How can we investigate drugs and pathways involved in aging? Watch the Axxam Boot Camp webinar on Aging and discover the portfolio of assays can assist you in achieving this goal:  https://lnkd.in/e3DDQKcv #AgingRevolution #Longevity #Milanlongevitysummit #DrugDiscovery #Senolytics #HighContentImaging #Webinar #Axxam

#bioGUNE_Talent | 🎖️ Outstanding research recognized at First #CIBER_ISCIII Youth Symposium From May 8th to 10th in Vigo, postdoctoral researcher Naroa Goikoetxea Usandizaga from the 'Liver Disease Lab' at #CICbioGUNE BRTA - Basque Research & Technology Alliance, led by Mariluz Martinez-Chantar, was honored for her research on cholestatic liver diseases 🔎 Her groundbreaking study on primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) revealed that changes in magnesium (Mg2+) balance, regulated by Cyclin M4 (CNNM4), are crucial. Targeted therapy showed promise in restoring Mg2+ balance, reducing inflammation, and liver fibrosis in animal models, paving the way for new treatments 🔗 For more information, visit: http://ow.ly/VnG250RJqRY Congrats, Naroa! 👏🎉

The Clinical Laboratory Services Market is anticipated to hit a whopping USD 380.65 billion by 2029! The surge in chronic and infectious diseases, coupled with the demand for precise and early diagnosis methods, fuels this growth. Additionally, the rising burden of cancer is set to further drive the demand for clinical diagnostics. Want to dive deeper into the reports? Click here for more insights: https://lnkd.in/deYrp734 Major Players: OPKO Health, Inc. | Quest Diagonostics | Labcorp | NeoGenomics Laboratories | Myriad Genetics #Clinicallaboratory #healthcare #marketresearch #marketintelligence #mordorintelligence

👴 👵“Forever young?” Targeting the hallmarks of aging   This year Fernanda Ricci, PhD attended the Longevity Summit in Milan (March 2024), alongside peers and international experts, with the main focus on biological control of aging and groundbreaking therapeutics. During this fascinating meeting there were numerous highlights of promising therapies for aging and age-related diseases. Check below the key insights that caught Fernanda’s attention at the conference! 🗝 Key takeaway: Aging is under biological control. By identifying the pathways that regulate aging, we can develop therapeutics to delay aging and mitigate age-related diseases. 📹 How can we investigate drugs and pathways involved in aging? Watch the Axxam Boot Camp webinar on Aging and discover the portfolio of assays can assist you in achieving this goal:  https://lnkd.in/eryjXbUB #AgingRevolution #Longevity #Milanlongevitysummit #DrugDiscovery #Senolytics #HighContentImaging #Webinar #Axxam