Axion BioSystems’ Post

Beautiful introduction! Looking forward to learn from rest of the videos in this series.

🔬 Advancing Pain Research with DRG Cell Recordings Our San Diego platform excels in recording from dorsal root ganglion (DRG) cells, providing essential data for drug development. We specialize in recordings from various tissue sources, including those from larger animals, which are critical for generating data with greater translational relevance. By studying these complex systems, we gain richer insights into pain mechanisms, leading to more accurate predictions of human responses. 🔗 Read more: Discover the full potential of DRG sensory neuron recordings and how they can accelerate your pain drug discovery efforts: https://lnkd.in/eHSkY3bP ✉️ Are you currently studying a compound targeting Pain? Reach out to contact@neuroservices-alliance.com or schedule an introductory meeting with us: https://lnkd.in/eEkM9xDN #Neuroscience #PainResearch #CNS #Electrophysiology #DRG

Live-cell analysis of 3D models is revolutionizing our understanding of this devastating condition by providing more biologically relevant insights. In addition to better in-vitro models, improved assays and technologies that can capture the data generated by these models are vital to accelerate therapeutic developments for Alzheimer's Disease. Download this white paper to learn how live cell analysis of 2D and 3D models provides a better understanding of the mechanism of AD by addressing the limitations of traditional methods. Read now: https://ow.ly/kqnY50Q8T8b #alzheimers #neuroscience #3dcellmodels #livecellanalysis

DRG are the first “integration center” on the pain pathways. This is the first level where pharmacological modulation can take place. We offer all the ways (in vitro and in vivo) to investigate the pharmacological properties of your compound on sensory neurons!

Just Published: Our new Lab Note on performing Calcium Flux assays with our new iCell Sensory Neurons. Let me know if you want to discuss how our iCell Sensory Neurons can help your pain research

⏰ It's not too late to register! You won't want to miss our webinar, "iForum™ Innovation Showcase 2024: Implementing Human iPSC Models to Speed Drug Discovery and Improve Clinical Translation" on January 30, 2024 (9:00 AM- 11:00 AM EST). Join us as FCDI's leading scientists dive into the transformative power of advanced biological models. We're talking about breakthroughs that are reshaping our approach to accelerating drug discovery across cardiac, hepatic, neural, and immune systems. Come for specific talks or immerse yourself in the entire 2-hour presentation – the choice is yours! 👉 VIEW DETAILED AGENDA AND REGISTER NOW! https://ow.ly/vupM50Qs8sP #StemCells #iPSC #DrugDiscovery #DrugDevelopment #Neuroscience #DiseaseModeling #3DCellCuture #Neuroinflammation #SafetyPharmacology #CardiacSafety #CardioTox

We are proud to introduce the Simoa® BD-Tau Advantage PLUS Assay! 🧠➕ This groundbreaking tool advances neurodegenerative research with its ultrasensitive and selective measurement of brain-derived tau (BD-Tau) levels in serum, plasma, and cerebrospinal fluid (CSF) samples. The Simoa® BD-Tau Advantage PLUS Assay is a powerful asset for furthering translational and clinical research in Alzheimer’s Disease (AD) and other neurodegenerative conditions. Learn more about how this innovative assay can elevate your research and drive new discoveries in the fight against neurodegenerative diseases. https://bit.ly/3A8tEhq #NeuroScience #AlzheimersResearch #Alzheimers

Is the pathogenesis of Parkinson’s disease rooted in early neurodevelopmental defects? Congratulations to Isabel Rosety, Alise Žagare, Jens Schwamborn, and their team, for the important paper using patient-specific midbrain #organoids carrying a heterozygous GBA-N370S mutation in the GBA1gene to explore the pathophysiology of Parkinson’s disease and suggest the potential for new therapeutic approaches. Visit our website to learn more and discover how the team used Axion’s #MaestroMEA platform to perform complex electrophysiological experiments on the 3D organoids with no labels, dyes, or complicated steps. 📝https://bit.ly/4bqlv63 #neuroscience #stemcells #parkinsonsresearch #biotech

If you're at the Cell Press "Engineering development and disease in organoids" symposium this week, come by my poster on Wednesday or swing by the Axion BioSystems booth throughout the week to learn more about our organoid solutions and tell us what you're working on! #organoids #neuroscience #stemcell #cellsymposia

Our latest study, recently published in the International Journal of Human Anatomy, delves into the promising realm of pharmaceutical intervention targeting Ca2+/cAMP signaling interaction. 📑 This groundbreaking research sheds light on its potential benefits in combating neurodegeneration and age-related diseases. 💊 🧬 The study uncovers unexpected findings regarding Ca2+ channel blockers (CCB) and their impact on neurotransmission. Despite their intended role in reducing Ca2+ influx, low concentrations of CCB paradoxically increased nerve-mediated responses. This phenomenon, termed the "calcium paradox," was elucidated through our exploration of the Ca2+/cAMP signaling interaction. 📈 Notably, our original paper, published in Cell Calcium in 2013, has garnered significant attention, appearing four times in ScienceDirect TOP 25 Hottest Articles lists. 🌟 💡 These findings hold immense potential for revolutionizing our approach to neurodegenerative diseases and aging-related ailments. 💪 Dive deeper into the study by accessing the article here: https://lnkd.in/gARN6emC #Research #Neuroscience #Aging #Pharmacology #Science #StudyAlert #AcademicResearch