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''I have little illusion in [mental health treatments], let alone the antidepressants drama. You have to take them for at least six weeks, often with all the side effects, only to conclude they don’t do anything..'' #Depression, affecting over 300 million globally, remains a significant and complicated challenge with up to 30% of patients finding current treatments, including #psychotherapy and #antidepressants not fully effective. A recent study explored the perspectives and experiences of 11 patients undergoing a double-blind randomised clinical trial with a single session of #psilocybin treatment for treatment-resistant depression, offering insights into the treatment's effectiveness and areas for improvement. The findings reveal that patients faced challenges with trust-building, managing expectations, and navigating the profound and often overwhelming experience. They expressed a general desire for a more comprehensive treatment approach, which may include multiple, dose-escalated, psilocybin sessions, and ongoing therapy to integrate and make sense of their experiences. This study not only reinforces the importance of substance, set and setting, as well as sustained therapeutic support in the outcomes of psychedelic therapy but also the crucial need for a more personalised treatment approach that considers and addresses the unique situation and needs of each individual. #Psychedelics #PsychedelicTherapy #PsychedelicResearch #PsychedelicAssistedTherapy #PsychedelicIntegration #MentalHealth #PsychedelicMedicine #MentalHealthSupport #Wellness #HealingJourney #Wellbeing

Patient perspectives and experiences with psilocybin treatment for treatment-resistant depression: a qualitative study - Scientific Reports

Patient perspectives and experiences with psilocybin treatment for treatment-resistant depression: a qualitative study - Scientific Reports

nature.com

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