𝐕𝐢𝐬𝐮𝐚𝐥 𝐩𝐚𝐭𝐜𝐡 𝐜𝐥𝐚𝐦𝐩 𝐫𝐞𝐜𝐨𝐫𝐝𝐢𝐧𝐠 𝐢𝐧 𝐥𝐮𝐦𝐛𝐚𝐫 𝐬𝐩𝐢𝐧𝐚𝐥 𝐜𝐨𝐫𝐝 𝐬𝐥𝐢𝐜𝐞𝐬 The mechanisms linking adolescent stress and pain remain poorly understood. This recent study out of University of Cincinnati College of Medicine by Kyle Harbour 𝘦𝘵 𝘢𝘭 investigated the short- and long-term effects of corticosterone (CORT) on the excitability of GABAergic and presumed glutamatergic neurons of the spinal superficial dorsal horn (SDH) in Gad1-GFP mice at postnatal days (P)21-P34. The lumbar spinal cord (L3-L5) was immersed in low melting point agarose and parasagittal slices (~300µm) cut in ice-cold dissection solution using the Campden 7000smz-2 vibrating microtome. Gad1-GFP neurons and non-GFP neurons were identified in laminae I-II via the presence or absence of GFP, and both cell types were visualized for patch-clamp recording via infrared illumination. Amongst several findings, data suggested that Corticosterone evokes slow effects on spontaneous synaptic transmission in the mouse Superficial Dorsal Horn in a sex dependent manner, as evidenced by an increase in mEPSC frequency in males and a decrease in mIPSC amplitude in females when pooling data across cell types. Full paper below. Info on #vibratome: https://lnkd.in/eaqNEeG3 #neuroscience #neurosciences
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And that's a wrap! The Campden Instruments team is now all back across the pond after an incredible time at #SfN2024! We want to thank all of our customers, both old and new, for stopping by our booth! And of course thank you Society for Neuroscience for putting on a great meeting! We loved being able to show off our newly engineered 9000smz vibrating microtome and all of the new features it has! If you haven't done so already, make sure to register your interest in it, so when we officially launch, you can be the first to know! Register here: https://ow.ly/Ojb850TKMHJ
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Hello Day 3 #SfN2024! We are past the halfway mark and are still going strong! Come by our booth to check out the NHP CANTAB station and the 2nd generation Bussey-Saksida touch screen chambers!
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We are nearing towards the end of #SfN2024 Exhibition Day 2 and would love to further highlight our 9000smz vibrating microtome!
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#SfN2024 Exhibition Day 1 is in the books! Campden Instruments has four employees that made the journey across the pond: Ian Davies, PhD 🧠, Cassandra Deichsel, Dave, and Paul! We are very happy to have the opportunity to have our engineers attend. If you have any pressing issues for them, make sure to stop by the booth (right behind the Society for Neuroscience booth) today! Here is to a great start to Day 2!
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Neuroscience 2024 is almost here, and we are excited to bring you a sneak peek of our new 9000smz Vibrating Microtome. Be sure to stop by booth 617 to see why it is a cut above the rest! #SfN24 Interested in the 9000smz? Let us know - we would love to keep you up to date! https://lnkd.in/gdXujwqR
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Last week, Campden Instruments was represented by our partner Hong Kong Plexon Inc, at the 17th annual Chinese Neuroscience Society conference in Suzhou, China! On display were our second generation Bussey-Saksida Touch Screen Chambers! Did you know that they can easily be modified to be usable with tethered animals?! Therefore, you can easily upgrade the behavioural tests you perform in your optogenetic or in vivo e-phys experiments! Want to learn more? Make sure to visit our booth at the upcoming #SfN2024 conference in Chicago. Or better yet, book a meeting with our sales team to learn more! https://lnkd.in/eUbqvf7T
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