Capital Rx’s Post

"Understanding the essential role of paracetamol in pain relief and fever management. Here's why it's a go-to medication for millions: safe, effective, and accessible. Learn more about its benefits and responsible use. #Healthcare #Pharmacology #PainManagement" #pharmaceuticaldrugs

🔆 #Event_At_The_Pharmacy: 𝗔𝗻 𝗲𝗹𝗱𝗲𝗿𝗹𝘆 𝗺𝗮𝗻 comes to your pharmacy with a complaint of 𝘀𝗸𝗶𝗻 𝗱𝗶𝘀𝗰𝗼𝗹𝗼𝗿𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 𝘆𝗲𝗹𝗹𝗼𝘄𝗶𝗻𝗴 𝗼𝗳 𝘁𝗵𝗲 𝗲𝘆𝗲𝘀 after taking medication along with several drugs to 𝘁𝗿𝗲𝗮𝘁 𝘂𝗿𝗶𝗻𝗮𝗿𝘆 𝘁𝗿𝗮𝗰𝘁 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻𝘀. 𝙒𝙝𝙖𝙩 𝙞𝙨 𝙩𝙝𝙞𝙨 𝙢𝙚𝙙𝙞𝙘𝙖𝙩𝙞𝙤𝙣, 𝙖𝙣𝙙 𝙬𝙝𝙖𝙩 𝙝𝙖𝙥𝙥𝙚𝙣𝙚𝙙 𝙩𝙤 𝙩𝙝𝙚 𝙢𝙖𝙣 ⁉️ 💊 The medication is: #Phenazopyridine. ☑️ The reason for skin and eye discoloration in yellow is: Accumulation of phenazopyridine. ☑️ Accumulation occurs: ● Due to a decline in kidney function, especially in the elderly. ● Or due to using the medication for longer than #two_days. Here, the medication should be stopped immediately ✋🏻🚫 📍𝗥𝗲𝗳𝗲𝗿𝗲𝗻𝗰𝗲𝘀: 🔵 https://lnkd.in/eiFEUPGW 🔵 https://lnkd.in/ezcEPWEi 🔵 https://lnkd.in/euMeq_23 #phenazopyridine #kidneydisease #kidney #pharmacist #pharmacy #medicationsafety #medication #urinarytractinfection #communitypharmacy

Benefit of combination of ketamine and propofol in procedural sedation

Daily Critical Care Pearls #105: Ketamine and Propofol Combination 💉These two medications are frequently given together for procedural sedation in the Emergency Department and elsewhere. This combination is sometimes called “Ketofol”. 💉In this combination, propofol serves to provide sedation while ketamine serves to provide analgesia without increasing the respiratory depressant effects of propofol.  💉An additional benefit of the combination is that the hypotension from propofol may be partially offset by the positive cardiovascular effects of ketamine. 💉The ratio of ketamine to propofol varies widely with some studies using 1:1, some using 1:10, and several more at various points in between this range. #criticalcare #pharmacy #medicine #clinicalpharmacy #pearls

Do you have Type 1 Diabetes and wish you could take medications that you see on TV like Ozempic, Mounjaro, Jardiance, and Farxiga? Why can't T1D's take those medications? To the frustration of many, these medications haven’t yet been approved by the FDA for use in type 1 diabetes because there haven’t been enough studies to demonstrate that the benefits outweigh the risks. Additionally, a few drugs were briefly approved in Europe, but were ultimately withdrawn due to safety concerns and commercial reasons. These setbacks were just the beginning. Learn about off-label medications and adjunctive therapies as well as their benefits & risks: https://bit.ly/3XAN9sK . . . . #myAMCR #HeadlandsResearchAMCR #OffLabel #OffLabelDrugs #AdjunctiveTherapies #Type1DiabetesTreatment #DiabetesTreatments #DiabetesMedication #DiabetesHealth #DiabetesManagement

💉 Propofol is the most commonly used intravenous anesthetic that is currently used in various procedural sedations, including dental sedation. Its use is preferred owing to advantages of rapid onset of action, short duration of action, and easy titration. However, despite these advantages, it carries risks of respiratory depression and hemodynamic. 💉 Ketamine is an anesthetic preferred owing to its analgesic effect and the maintenance effect on airway reflex. Nevertheless, its clinical use is controversial because of disadvantages of dissociative anesthesia, postoperative hallucinations, sympathomimetic effects, and stimulations of saliva and secretions instability. ⚠️ Use of a combination of ketamine and propofol (ketofol) as a sedative has been attracting attention in various clinical fields. The combination of ketamine and propofol can reduce the dose of each drug and compensate for the disadvantages of the other through the antagonistic characteristics of both drugs, resulting in beneficial results for successful sedation. 🎯 Ketofol has been used in bolus form to provide sedation and analgesia for painful procedures in the emergency room. A propofol-ketamine infusion has also been used to provide anaesthesia for coronary artery surgery. 🟢 For amazing clinical pearls, you can join my WhatsApp group: 👇🏻 https://lnkd.in/d3axttDk 🔴 You can also follow me on "YouTube and Instagram" as well: YouTube👉🏼: https://lnkd.in/d4Fx3vCr Instagram👉🏼: https://lnkd.in/dy6krB4q #icu #icucare #criticalcare #ketamine #propofol #emergencymedicine #anesthesia #sedation #ketofol #clinicalpharmacist #hospitalpharmacy #clinicalpearls #meded

How to Reduce Alprazolam Safely! After long-term treatment, rapidly reducing the dose or stopping alprazolam abruptly can trigger severe withdrawal symptoms, which can be dangerous. To avoid these risks, it is crucial to taper off alprazolam gradually. Typically, the dose should be reduced by 0.5 mg every three days. For those on alprazolam for a long time, switching to a longer-acting medication like clonazepam or diazepam before tapering can help minimize withdrawal effects and ensure safety. #pharmacy #medicationsafety #patientcare #pharmd

Daily Critical Care Pearls #69: Management of Angioedema from ACE Inhibitors ✔️ Protect the airway with endotracheal intubation. Nothing else matters. ✔️ Antihistamines, glucocorticoids, and epinephrine don’t work. ✔️ Icatibant doesn’t affect clinically meaningful endpoints. ✔️ Ecallantide doesn’t work. ✔️ Fresh frozen plasma might help. ✔️ If you hear stridor, see that the patient is drooling, using accessory muscles to breathe, or has edema of the tongue or floor of the mouth, assume that the physician will want to immediately intubate the patient and obtain the necessary medications to assist with this process (Etomidate-Induction, Succinylcholine-paralysis) ✔️ Obtain appropriate sedation to use post intubation ✔️ Be prepared for hypotension to occur after intubation and have a liter of normal saline and a vasopressor readily accessible. #criticalcare #pharmacy #medicine #clinicalpharmacy #pearls

Daily Critical Care Pearls #77: Severe Alcohol Withdrawal - Part 2 - (Non-benzodiazepine treatments: Dexmedetomidine, phenobarbital, propofol) 📌 Dexmedetomidine: Blunts Tremor Tachycardia Anxiety Agitation, Provides sedation, Reduces benzodiazepine requirements, Does not protect against seizure risk! 📌 Phenobarbital: Very helpful in refractory DT when benzos fail, Risk of intubation rises greatly - be prepared for intubation if phenobarbital is added. 📌 Propofol: Intubation is required for use. Use as induction agent (1-2 mg/kg IV) then continuous infusion at a dose that controls symptoms within the normal range. #criticalcare #pharmacy #medicine #clinicalpharmacy #pearls

Our 'practice points' activity provides a comprehensive overview of oral antiviral therapy in COVID-19 management, complete with case studies for practical application. https://bit.ly/49dTopz #cpd #cme #meded #gp #covid19